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Akademický článek

Multiple linear epitopes (B-cell, CTL and Th) of JEV expressed in recombinant MVA as multiple epitope vaccine induces a protective immune response

Autor: Wang Fengjuan, Feng Xiuli, Zheng Qisheng, Hou Hongyan, Cao Ruibing, Zhou Bin, Liu Qingtao, Liu Xiaodong, Pang Ran, Zhao Jin, Deng Wenlei, Chen Puyan

Publikováno v: Virology Journal, Vol 9, Iss 1, p 204 (2012)

Abstract Epitope-based vaccination might play an important role in the protective immunity against Japanese encephalitis virus (JEV) infection. The purpose of the study is to evaluate the immune characteristics of recombinant MVA carrying multi-epito

Externí odkaz: https://doaj.org/article/e3e6e87692ff4d5da11da316f548e599

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Akademický článek

Mutation of putative N-Linked Glycosylation Sites in Japanese encephalitis Virus Premembrane and Envelope proteins enhances humoral immunity in BALB/C mice after DNA vaccination

Autor: Gu Jinyan, Cao Ruibing, Chen Puyan, Zhang Yu

Publikováno v: Virology Journal, Vol 8, Iss 1, p 138 (2011)

Abstract Swine are an important host of Japanese encephalitis virus (JEV). The two membrane glycoproteins of JEV, prM and E, each contain a potential N-linked glycosylation site, at positions N15 and N154, respectively. We constructed plasmids that c

Externí odkaz: https://doaj.org/article/dd856bf070aa44279b57bdb2cbc0a25c

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Akademický článek

The Meq oncoprotein of Marek's disease virus interacts with p53 and inhibits its transcriptional and apoptotic activities

Autor: Ding Chan, Chen Hongjun, Jin Yamei, Shao Donghua, Shi Zixue, Qiu Yafeng, Shen Yang, Li Xiangdong, Deng Xufang, Li Li, Chen Puyan, Ma Zhiyong

Publikováno v: Virology Journal, Vol 7, Iss 1, p 348 (2010)

Abstract Background Marek's disease virus (MDV) is an oncogenic herpesvirus, which causes malignant lymphoma in chickens. The Meq protein of MDV, which is expressed abundantly in MDV-infected cells and in Marek's disease (MD) tumor cells, functions a

Externí odkaz: https://doaj.org/article/382c2bdc052c4108a23f0ecdf648a191

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