The 4EHP-mediated translational repression of cGAS impedes the host immune response against DNA viruses.

Autor: Ladak RJ; Department of Biochemistry, Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, QC H3A 1A3, Canada., Choi JH; Department of Biochemistry, Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, QC H3A 1A3, Canada., Luo J; Department of Biochemistry, Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, QC H3A 1A3, Canada., Chen OJ; Department of Biochemistry, Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, QC H3A 1A3, Canada., Mahmood N; Department of Biochemistry, Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, QC H3A 1A3, Canada., He AJ; Department of Physiology, McGill University, Montreal, QC H3A 1A2, Canada., Naeli P; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast BT9 7AE, United Kingdom., Snell PH; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast BT9 7AE, United Kingdom., Bayani E; Department of Ophthalmology and Visual Sciences, McGill University, Montreal, QC H3A 2B4, Canada., Hoang HD; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, Children's Hospital of Eastern Ontario Research Institute, University of Ottawa, Ottawa, ON K1H 8L1, Canada., Alain T; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, Children's Hospital of Eastern Ontario Research Institute, University of Ottawa, Ottawa, ON K1H 8L1, Canada., Teodoro JG; Department of Biochemistry, Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, QC H3A 1A3, Canada., Wang J; Center of Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China., Zhang X; Department of Biochemistry, Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, QC H3A 1A3, Canada., Jafarnejad SM; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast BT9 7AE, United Kingdom., Sonenberg N; Department of Biochemistry, Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, QC H3A 1A3, Canada.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Nov 26; Vol. 121 (48), pp. e2413018121. Date of Electronic Publication: 2024 Nov 19.

Germline Missense Variants in CDC20 Result in Aberrant Mitotic Progression and Familial Cancer.

Autor: Chen OJ; Goodman Cancer Institute, McGill University, Montréal, Québec, Canada.; Department of Biochemistry, McGill University, Montréal, Québec, Canada., Castellsagué E; Department of Human Genetics, McGill University, Montréal, Québec, Canada.; Division of Medical Genetics and Cancer Axis, Lady Davis Institute, Segal Cancer Centre, Jewish General Hospital, Montréal, Québec, Canada.; Translational Research Laboratory, Catalan Institute of Oncology, Bellvitge Institute for Biomedical Research, L'Hospitalet de Llobregat, Barcelona, Spain., Moustafa-Kamal M; Goodman Cancer Institute, McGill University, Montréal, Québec, Canada.; Department of Biochemistry, McGill University, Montréal, Québec, Canada., Nadaf J; McGill University and Génome Québec Innovation Centre, Montréal, Québec, Canada., Rivera B; Cancer Axis, Lady Davis Institute, Jewish General Hospital, Montréal, Québec, Canada.; Hereditary Cancer Programme, Catalan Institute of Oncology, Bellvitge Institute for Biomedical Research, L'Hospitalet de Llobregat, Barcelona, Spain.; Gerald Bronfman Department of Oncology, McGill University, Montréal, Québec, Canada., Fahiminiya S; Department of Human Genetics, McGill University, Montréal, Québec, Canada.; Cancer Research Program, Research Institute of the McGill University Health Centre, Montréal, Québec, Canada., Wang Y; Goodman Cancer Institute, McGill University, Montréal, Québec, Canada.; Department of Biochemistry, McGill University, Montréal, Québec, Canada., Gamache I; Goodman Cancer Institute, McGill University, Montréal, Québec, Canada., Pacifico C; Goodman Cancer Institute, McGill University, Montréal, Québec, Canada.; Department of Biology, McGill University, Montréal, Québec, Canada., Jiang L; Cancer Axis, Lady Davis Institute, Jewish General Hospital, Montréal, Québec, Canada.; Department of Epidemiology, Biostatistics & Occupational Health, McGill University, Montréal, Québec, Canada., Carrot-Zhang J; Department of Human Genetics, McGill University, Montréal, Québec, Canada.; Cancer Research Program, Research Institute of the McGill University Health Centre, Montréal, Québec, Canada., Witkowski L; Department of Human Genetics, McGill University, Montréal, Québec, Canada.; Division of Medical Genetics and Cancer Axis, Lady Davis Institute, Segal Cancer Centre, Jewish General Hospital, Montréal, Québec, Canada., Berghuis AM; Department of Biochemistry, McGill University, Montréal, Québec, Canada.; Centre de Recherche en Biologie Structurale, McGill University, Montréal, Québec, Canada.; Department of Microbiology and Immunology, Montréal, Québec, Canada., Schönberger S; Department of Pediatric Hematology and Oncology, Pediatrics III, University Hospital of Essen, University of Duisburg-Essen, Essen, Germany., Schneider D; Clinic of Pediatrics, Dortmund Municipal Hospital, Dortmund, Germany., Hillmer M; Institute of Human Genetics, University of Ulm & Ulm University Medical Center, Ulm, Germany., Bens S; Institute of Human Genetics, University of Ulm & Ulm University Medical Center, Ulm, Germany., Siebert R; Institute of Human Genetics, University of Ulm & Ulm University Medical Center, Ulm, Germany., Stewart CJR; Department of Histopathology, King Edward Memorial Hospital, and School for Women's and Infants' Health, University of Western Australia, Perth, Australia., Zhang Z; Institute of Cancer Research, London, United Kingdom., Chao WCH; Faculty of Health Sciences, University of Macau, Macau SAR, China., Greenwood CMT; Cancer Axis, Lady Davis Institute, Jewish General Hospital, Montréal, Québec, Canada.; Department of Epidemiology, Biostatistics & Occupational Health, McGill University, Montréal, Québec, Canada.; Departments of Oncology and Human Genetics, McGill University, Montréal, Québec, Canada., Barford D; Institute of Cancer Research, London, United Kingdom., Tischkowitz M; Department of Medical Genetics, National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge, Cambridge, United Kingdom., Majewski J; Department of Human Genetics, McGill University, Montréal, Québec, Canada.; Cancer Research Program, Research Institute of the McGill University Health Centre, Montréal, Québec, Canada., Foulkes WD; Department of Human Genetics, McGill University, Montréal, Québec, Canada.; Division of Medical Genetics and Cancer Axis, Lady Davis Institute, Segal Cancer Centre, Jewish General Hospital, Montréal, Québec, Canada.; Program in Cancer Genetics, Department of Oncology and Human Genetics, McGill University, Montréal, Québec, Canada.; Division of Medical Genetics and Cancer Research Program, Research Institute of the McGill University Health Centre, Montréal, Québec, Canada., Teodoro JG; Goodman Cancer Institute, McGill University, Montréal, Québec, Canada.; Department of Biochemistry, McGill University, Montréal, Québec, Canada.; Department of Microbiology and Immunology, Montréal, Québec, Canada.

Publikováno v: Cancer research [Cancer Res] 2022 Oct 04; Vol. 82 (19), pp. 3499-3515.

Elevated V-ATPase Activity Following PTEN Loss Is Required for Enhanced Oncogenic Signaling in Breast Cancer.

Autor: Mohammad AH; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.; Department of Biochemistry, McGill University, Montreal, Quebec, Canada., Kim SH; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada., Bertos N; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.; Molecular Oncology Group, McGill University Health Centre, Montreal, Quebec, Canada., El-Assaad W; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.; Department of Biochemistry, McGill University, Montreal, Quebec, Canada., Nandi I; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.; Department of Biochemistry, McGill University, Montreal, Quebec, Canada., Smith H; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada., Yang J; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.; Department of Biochemistry, McGill University, Montreal, Quebec, Canada., Chen OJ; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.; Department of Biochemistry, McGill University, Montreal, Quebec, Canada., Gamache I; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada., Rao T; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.; Department of Biochemistry, McGill University, Montreal, Quebec, Canada., Gagnon B; Department of Family Medicine and Emergency Medicine, Laval University, Laval, Quebec, Canada., Gruosso T; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.; Molecular Oncology Group, McGill University Health Centre, Montreal, Quebec, Canada., Tremblay ML; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.; Department of Biochemistry, McGill University, Montreal, Quebec, Canada., Sonenberg N; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.; Department of Biochemistry, McGill University, Montreal, Quebec, Canada., Guiot MC; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.; McGill University Health Centre, McGill University, Montreal, Quebec, Canada., Muller W; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.; Department of Biochemistry, McGill University, Montreal, Quebec, Canada., Park M; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.; Department of Biochemistry, McGill University, Montreal, Quebec, Canada.; Molecular Oncology Group, McGill University Health Centre, Montreal, Quebec, Canada.; McGill University Health Centre, McGill University, Montreal, Quebec, Canada.; Department of Oncology, McGill University, Montreal, Quebec, Canada., Teodoro JG; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada. jose.teodoro@mcgill.ca.; Department of Biochemistry, McGill University, Montreal, Quebec, Canada.

Publikováno v: Molecular cancer research : MCR [Mol Cancer Res] 2020 Oct; Vol. 18 (10), pp. 1477-1490. Date of Electronic Publication: 2020 Jun 25.

Termination of second-trimester pregnancy by mifepristone combined with misoprostol versus intra-amniotic injection of ethacridine lactate (Rivanol®): a systematic review of Chinese trials.

Autor: Hou SP; Department of Gynecology and Obstetrics, The Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China., Fang AH, Chen QF, Huang YM, Chen OJ, Cheng LN

Publikováno v: Contraception [Contraception] 2011 Sep; Vol. 84 (3), pp. 214-23. Date of Electronic Publication: 2011 Mar 11.