Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Chen Kung Chou"'
Supplementary Data from Aurora-A Overexpression in Mouse Liver Causes p53-Dependent Premitotic Arrest during Liver Regeneration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d01d7c70d56c321e0102eaf00361f16
https://doi.org/10.1158/1541-7786.22518507
https://doi.org/10.1158/1541-7786.22518507
Aurora-A, a serine-threonine kinase, is frequently overexpressed in human cancers, including hepatocellular carcinoma. To study the phenotypic effects of Aurora-A overexpression on liver regeneration and tumorigenesis, we generated transgenic mice ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21acc3ee5dbdf7a6758ada13b4e6e845
https://doi.org/10.1158/1541-7786.c.6541956
https://doi.org/10.1158/1541-7786.c.6541956
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19718 (2011)
Aurora-A, a centrosomal serine-threonine kinase, orchestrates several key aspects of cell division. However, the regulatory pathways for the protein stability and kinase activity of Aurora-A are still not completely understood. In this study, PUM2, a
Externí odkaz:
https://doaj.org/article/2a1e318b206f4700b35246dfdbef3258
VEGFA upregulates FLJ10540 and modulates migration and invasion of lung cancer via PI3K/AKT pathway.
Autor:
Chang-Han Chen, Jin-Mei Lai, Teh-Ying Chou, Cheng-Yu Chen, Li-Jen Su, Yuan-Chii Lee, Tai-Shan Cheng, Yi-Ren Hong, Chen-Kung Chou, Jacqueline Whang-Peng, Yu-Chung Wu, Chi-Ying F Huang
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5052 (2009)
BACKGROUND: Lung adenocarcinoma is the leading cause of cancer-related deaths among both men and women in the world. Despite recent advances in diagnosis and treatment, the mortality rates with an overall 5-year survival of only 15%. This high mortal
Externí odkaz:
https://doaj.org/article/6852ce5f99b5491889b737a656eea3fa
Autor:
Hurng-Yi Wang, Huan-Chieh Chien, Naoki Osada, Katsuyuki Hashimoto, Sumio Sugano, Takashi Gojobori, Chen-Kung Chou, Shih-Feng Tsai, Chung-I Wu, C-K James Shen
Publikováno v:
PLoS Biology, Vol 5, Iss 2, p e13 (2007)
Brain-expressed genes are known to evolve slowly in mammals. Nevertheless, since brains of higher primates have evolved rapidly, one might expect acceleration in DNA sequence evolution in their brain-expressed genes. In this study, we carried out ful
Externí odkaz:
https://doaj.org/article/33f9b05f0c024c3b89a38d87fdb7cb12
Gluconeogenesis, lipogenesis, and HBV replication are commonly regulated by PGC-1α-dependent pathway
Autor:
Hong Jhih Jhuang, Ann-Ping Tsou, Jin Mei Lai, Kuan-Ting Lin, Wei-Hsiang Hsu, Kuen Haur Lee, Feng Sheng Wang, Chen-Kung Chou, Sheau Farn Yeh, Chi Ying F. Huang, Shih-Lan Hsu
Publikováno v:
Oncotarget
// Hong-Jhih Jhuang 1, * , Wei-Hsiang Hsu 2, * , Kuan-Ting Lin 3 , Shih-Lan Hsu 4 , Feng-Sheng Wang 5 , Chen-Kung Chou 6 , Kuen-Haur Lee 8 , Ann-Ping Tsou 9 , Jin-Mei Lai 7 , Sheau-Farn Yeh 1 , Chi-Ying F. Huang 2, 3, 9 1 Institute of Biochemistry an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3601091f0a9fb97cf393a579b0ef4a3b
https://doi.org/10.18632/oncotarget.3050
https://doi.org/10.18632/oncotarget.3050
Publikováno v:
Biochemical Journal. 433:187-196
The transcription factor NF-κB (nuclear factor κB) co-ordinates various gene expressions in response to diverse signals and is a critical regulator of inflammation and innate immunity. Several negative regulators of NF-κB have been identified as d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f8d8db4cad5929890ef9ce00763ce0
https://doi.org/10.1042/bj20100247
https://doi.org/10.1042/bj20100247
Autor:
Wen-Jeng Wu, Ching-I Kuan, Tzyh-Chyuan Hour, Huei-Ting Hu, Yan-Liang Lai, Chen-Kung Chou, Huang-Yao Tu, Yeong-Shiau Pu, Ju Ming Wang, Chang-Shen Lin, A-Mei Huang, Esta Sterneck
Publikováno v:
Biochemical Pharmacology. 80:325-334
Bladder cancer is the fourth most common type of cancer in men (ninth in women) in the United States. Cisplatin is an effective agent against the most common subtype, urothelial carcinoma. However, the development of chemotherapy resistance is a seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6c9b4f860aa9e886422231d8b7c1a60
https://doi.org/10.1016/j.bcp.2010.04.007
https://doi.org/10.1016/j.bcp.2010.04.007
Publikováno v:
Molecular Cancer Research. 7:678-688
Aurora-A, a serine-threonine kinase, is frequently overexpressed in human cancers, including hepatocellular carcinoma. To study the phenotypic effects of Aurora-A overexpression on liver regeneration and tumorigenesis, we generated transgenic mice ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7cf7926e882ab5616146147751f9dc4
https://doi.org/10.1158/1541-7786.mcr-08-0483
https://doi.org/10.1158/1541-7786.mcr-08-0483
Autor:
Yueh-Hsiung Kuo, Sheau-Farn Yeh, Chen-Kung Chou, Damodar Janmanchi, Chih-Hsiu Lin, Hsing-Chih Hsu, Pei-Chi Tseng
Publikováno v:
Biochemical Pharmacology. 76:1121-1133
An elevated level of macrophage inflammatory protein-1beta (MIP-1beta) induced by IL-1beta has been correlated with chronic hepatic inflammatory disease. However, molecular mechanism of IL-1beta-induced MIP-1beta expression in hepatic cells is obscur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1385055a790aeb336c7e814e7f32bd54
https://doi.org/10.1016/j.bcp.2008.08.023
https://doi.org/10.1016/j.bcp.2008.08.023