Zobrazeno 1 - 10
of 678
pro vyhledávání: '"Chen Jake"'
Autor:
Wu Xiaogang, Reinhard Christoph, Li Shuyu D., Huang Hui, Wei Tao, Pandey Ragini, Chen Jake Y.
Publikováno v:
Journal of Integrative Bioinformatics, Vol 9, Iss 2, Pp 113-125 (2012)
In many cases, crucial genes show relatively slight changes between groups of samples (e.g. normal vs. disease), and many genes selected from microarray differential analysis by measuring the expression level statistically are also poorly annotated a
Externí odkaz:
https://doaj.org/article/e5073047ccb748509604b1508ed1ea09
Publikováno v:
BMC Genomics, Vol 13, Iss Suppl 6, p S17 (2012)
Abstract Background Network pharmacology has emerged as a new topic of study in recent years. It aims to study the myriad relationships among proteins, drugs, and disease phenotypes. The concept of molecular connectivity maps has been proposed to est
Externí odkaz:
https://doaj.org/article/efbb529e861c49818c9824d613110b86
Autor:
Huang Hui, Wu Xiaogang, Sonachalam Madhankumar, Mandape Sammed N, Pandey Ragini, MacDorman Karl F, Wan Ping, Chen Jake Y
Publikováno v:
BMC Bioinformatics, Vol 13, Iss Suppl 15, p S2 (2012)
Abstract Background Over the past decade, pathway and gene-set enrichment analysis has evolved into the study of high-throughput functional genomics. Owing to poorly annotated and incomplete pathway data, researchers have begun to combine pathway and
Externí odkaz:
https://doaj.org/article/dbc93e6dfeb749349f2f8fa2c5dcbf6c
Publikováno v:
BMC Genomics, Vol 12, Iss Suppl 5, p S11 (2011)
Abstract Background Studies of toxicity and unintended side effects can lead to improved drug safety and efficacy. One promising form of study comes from molecular systems biology in the form of "systems pharmacology". Systems pharmacology combines d
Externí odkaz:
https://doaj.org/article/e2bdba99bf4741b88510b034a0f86eda
Publikováno v:
BMC Bioinformatics, Vol 12, Iss Suppl 12, p S7 (2011)
Abstract Background Along with the rapid digitalization of health data (e.g. Electronic Health Records), there is an increasing concern on maintaining data privacy while garnering the benefits, especially when the data are required to be published fo
Externí odkaz:
https://doaj.org/article/7c063e7955114215accc192c407422d8
Autor:
Zhang Fan, Chen Jake Y
Publikováno v:
BMC Bioinformatics, Vol 12, Iss Suppl 10, p S4 (2011)
Abstract Background Each organ has a specific function in the body. “Organ-specificity” refers to differential expressions of the same gene across different organs. An organ-specific gene/protein is defined as a gene/protein whose expression is s
Externí odkaz:
https://doaj.org/article/f0c7efd2a9424124acd7efadb8810c7b
Autor:
Escalon Barbara, Wilbanks Mitchell S, Guan Xin, Wu Xiaogang, Ai Junmei, Deng Youping, Chowbina Sudhir, Meyer Sharon A, Perkins Edward J, Chen Jake Y
Publikováno v:
BMC Genomics, Vol 11, Iss Suppl 3, p S4 (2010)
Abstract Background Military and industrial activities have lead to reported release of 2,4-dinitrotoluene (2,4DNT) into soil, groundwater or surface water. It has been reported that 2,4DNT can induce toxic effects on humans and other organisms. Howe
Externí odkaz:
https://doaj.org/article/de23a6ca4d86476898d805aa1785e884
Autor:
El-Araby, Rady E. a, b, Wasif, Komal a, c, Johnson, Rebecca a, c, Tu, Qisheng a, Aboushousha, Tarek b, Zhu, Zoe Xiaofang a, Chen, Jake a, d, ⁎
Publikováno v:
In Experimental Neurology August 2024 378
Publikováno v:
BMC Genomics, Vol 10, Iss Suppl 1, p S16 (2009)
Abstract Background Human protein-protein interaction (PPIs) data are the foundation for understanding molecular signalling networks and the functional roles of biomolecules. Several human PPI databases have become available; however, comparisons of
Externí odkaz:
https://doaj.org/article/9fe305f479594335ba828a18e9942773
Publikováno v:
BMC Bioinformatics, Vol 9, Iss Suppl 9, p S5 (2008)
Abstract Background New systems biology studies require researchers to understand how interplay among myriads of biomolecular entities is orchestrated in order to achieve high-level cellular and physiological functions. Many software tools have been
Externí odkaz:
https://doaj.org/article/c28415bd1c1a4b84a5bbcc40b5e447af