Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Chen H. Hsu"'
Publikováno v:
Artificial Organs. 17:234-239
Renal failure is characterized by the progressive decline in the capacity of the kidneys to eliminate toxic solutes. In parallel, the “uremic syndrome” is depicted by a functional disturbance of enzymes, organelles, cells, and organs. This leads
Publikováno v:
Nephrology Dialysis Transplantation. 17:265-270
Background. Hyperphosphataemia contributes to sec-ondary hyperparathyroidism and renal osteodystrophyin patients with end-stage renal disease (ESRD).Calcium salts are widely employed to bind dietaryphosphate (P) but they may promote positive netcalci
Autor:
A Dhondt, J van Kaer, P Vogeleere, Raymond Vanholder, Norbert Lameire, Chen H. Hsu, Griet Glorieux, R De Smet
Publikováno v:
Journal of the American Society of Nephrology. 9:1826-1831
End-stage renal disease is associated with a defect in immunologic functions. Previous studies have demonstrated that uremic ultrafiltrate (UUF) contains factors that suppress calcitriol synthesis and its biological actions. In the present study, the
Publikováno v:
Kidney International. 52:39-44
Effect of glyoxylate on the function of the calcitriol receptor and vitamin D metabolism. The biological action of calcitriol is mostly mediated through the interaction of the calcitriol receptor (VDR) with vitamin D response elements (VDREs) of targ
Publikováno v:
Kidney International. 50(5):1539-1545
Effect of Schiff base formation on the function of the calcitriol receptor. The genomic action of calcitriol is mediated through the interaction of the calcitriol receptor (VDR) with vitamin D response elements (VDREs) of the target genes. We have sh
Publikováno v:
Kidney International. 46:129-133
Inhibition of nuclear uptake of calcitriol receptor by uremic ultrafiltrate. The biological action of calcitriol is mediated through a hormone-receptor complex interacting with nuclear chromatin. Interaction of the calcitriol receptor (VDR) with VDR
Publikováno v:
American Journal of Physiology-Renal Physiology. 264:F662-F669
The biological actions of calcitriol and its receptor synthesis are believed to be mediated through the calcitriol-receptor complex interacting with nuclear chromatin of target cells. Thus inhibition of the receptor interaction with DNA could diminis
Autor:
Sanjeev Patel, Chen H. Hsu
Publikováno v:
Journal of the American Society of Nephrology. 3:947-952
The effect of uremic plasma ultrafiltrate on calcitriol synthesis was investigated. Renal 1 alpha-hydroxylase activity was measured in normal rats infused for 20 h with 20 mL of normal or uremic plasma ultrafiltrate. Renal 1 alpha-hydroxylase activit
Publikováno v:
American Journal of Physiology-Renal Physiology. 260:F596-F601
The effects of theophylline and sodium urate on metabolic production (PR) and clearance rate (MCR) of calcitriol were determined by the constant isotope infusion method in normal rats. Calcitriol PR was significantly reduced after infusion for 20 h o
Publikováno v:
American Journal of Kidney Diseases. 17:185-190
We studied calcitriol metabolism in white patients with chronic renal failure and in age- and sex-matched normal subjects. The plasma levels of calcitriol (21.9 +/- 1.6 pg/mL, n = 7, v control, 37.4 +/- 2.9 pg/mL, P less than 0.001), metabolic cleara