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Upper Bound on the Mutational Burden Imposed by a CRISPR-Cas9 Gene-Drive Element.

Autor: Overton MS; Department of Ecology, Behavior and Evolution, School of Biological Sciences, University of California San Diego, La Jolla, CA 92093., Guy SE; Department of Ecology, Behavior and Evolution, School of Biological Sciences, University of California San Diego, La Jolla, CA 92093.; Current address: Bionano Genomics, San Diego, CA 92121., Chen X; Department of Ecology, Behavior and Evolution, School of Biological Sciences, University of California San Diego, La Jolla, CA 92093.; Current address: Department of Entomology, University of Arizona, Tucson, Arizona, USA., Martsul A; Department of Ecology, Behavior and Evolution, School of Biological Sciences, University of California San Diego, La Jolla, CA 92093.; Current address: Illumina Inc., San Diego, CA 92122., Carolino K; Department of Ecology, Behavior and Evolution, School of Biological Sciences, University of California San Diego, La Jolla, CA 92093., Akbari OS; Department of Cell and Developmental Biology, School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA., Meyer JR; Department of Ecology, Behavior and Evolution, School of Biological Sciences, University of California San Diego, La Jolla, CA 92093., Kryazhimskiy S; Department of Ecology, Behavior and Evolution, School of Biological Sciences, University of California San Diego, La Jolla, CA 92093.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Nov 29. Date of Electronic Publication: 2023 Nov 29.