Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Chen, Varol"'
Autor:
Keren Cohen, Odelia Mouhadeb, Shani Ben Shlomo, Marva Langer, Anat Neumann, Noam Erez, Itay Moshkovits, Rotem Pelet, Daniel J. Kedar, Eli Brazowski, Martin Guilliams, Helen S. Goodridge, Nathan Gluck, Chen Varol
Publikováno v:
Cell Reports, Vol 37, Iss 7, Pp 110026- (2021)
Summary: Liver-resident macrophages Kupffer cells (KCs) and infiltrating Ly6Chi monocytes both contribute to liver tissue regeneration in various pathologies but also to disease progression upon disruption of orderly consecutive regeneration cascades
Externí odkaz:
https://doaj.org/article/fe477e9d24474de1a974c2e01f7c0b01
Autor:
Shoshi Bar-David, Liraz Larush, Noam Goder, Asaf Aizic, Ehud Zigmond, Chen Varol, Joseph Klausner, Shlomo Magdassi, Eran Nizri
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Abstract Localization of rectal tumors is a challenge in minimally invasive surgery due to the lack of tactile sensation. We had developed liposomal indocyanine green (Lip-ICG) for localization of rectal tumor. In this study we evaluated the effects
Externí odkaz:
https://doaj.org/article/48a320a22ddf425a9ab5891f7ba58bce
Publikováno v:
iScience, Vol 14, Iss , Pp 147-163 (2019)
Summary: Staphylococcus aureus is a major cause of infectious disease. Liver Kupffer cells (KCs) are responsible for sequestering and destroying S. aureus through the phagolysosomal pathway. Proteins belonging to the COMMD family emerge as key intrac
Externí odkaz:
https://doaj.org/article/6a04ac0e48e940c9a5f6327ba01e9c9e
Autor:
Irina Efimova, Inbar Steinberg, Isabel Zvibel, Anat Neumann, Dana Fernanda Mantelmacher, Daniel J. Drucker, Sigal Fishman, Chen Varol
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Glucose-dependent insulinotropic polypeptide (GIP) communicates information on energy availability from the gut to peripheral tissues. Disruption of its signaling in myeloid immune cells during high-fat diet (HFD)-induced obesity impairs energy homeo
Externí odkaz:
https://doaj.org/article/c4c8ac8433614300af4c6fba6c3d2e50
Autor:
Florent Ginhoux, Alexander Mildner, Emmanuel L. Gautier, Andreas Schlitzer, Claudia Jakubzick, Chen Varol, Calum Bain, Pierre Guermonprez
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Externí odkaz:
https://doaj.org/article/9b85d3eb5788448985bed55198e3907c
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Cholesterol-laden, foam macrophages constitute the most characteristic component of human atherosclerotic plaques. Persistent uptake of oxLDLs results in accumulation of lipid bodies inside the cells and determines their phenotype and subsequent func
Externí odkaz:
https://doaj.org/article/57847a2af1254d0cbae0ad28c7d4f885
Autor:
Mordehay Klepfish, Tamar Gross, Milena Vugman, Nikolaos A. Afratis, Sapir Havusha-Laufer, Eli Brazowski, Inna Solomonov, Chen Varol, Irit Sagi
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Liver fibrosis is characterized by the excessive accumulation of extracellular matrix (ECM) proteins and enzymes, especially fibrillary collagens, and represents a major cause of morbidity and mortality worldwide. Lysyl oxidases (LOXs) drive covalent
Externí odkaz:
https://doaj.org/article/83cb3c671bac499ca08859b5d75d220c
Autor:
Odelia Mouhadeb, Shani Ben Shlomo, Keren Cohen, Inbal Farkash, Shlomo Gruber, Nitsan Maharshak, Zamir Halpern, Ezra Burstein, Nathan Gluck, Chen Varol
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Ly6Chi monocyte tissue infiltrates play important roles in mediating local inflammation, bacterial elimination and resolution during sepsis and inflammatory bowel disease (IBD). Yet, the immunoregulatory pathways dictating their activity remain poorl
Externí odkaz:
https://doaj.org/article/c4d289a421fd4b6ab0ae01ed81d7e8d8
Autor:
Debby Reuveni, Yael Gore, Patrick S. C. Leung, Yael Lichter, Itay Moshkovits, Ayelet Kaminitz, Eli Brazowski, Eric Lefebvre, Pamela Vig, Chen Varol, Zamir Halpern, Oren Shibolet, Merrill Eric Gershwin, Ehud Zigmond
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The therapy of primary biliary cholangitis (PBC) has lagged behind other autoimmune diseases despite significant improvements in our understanding of both immunological and molecular events that lead to loss of tolerance to the E2 component of pyruva
Externí odkaz:
https://doaj.org/article/7c790b433c574dfab4927f871cf92829
Autor:
Nadine Graubardt, Milena Vugman, Odelia Mouhadeb, Gabriele Caliari, Metsada Pasmanik-Chor, Debby Reuveni, Ehud Zigmond, Eli Brazowski, Eyal David, Lousie Chappell-Maor, Steffen Jung, Chen Varol
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Monocyte-derived macrophages (MoMF) play a pivotal role in the resolution of acetaminophen-induced liver injury (AILI). Timely termination of neutrophil activity and their clearance are essential for liver regeneration following injury. Here, we show
Externí odkaz:
https://doaj.org/article/f14c89b1e5a647ac81222f098b893c48