Perioperative Systemic Therapy vs Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Alone for Resectable Colorectal Peritoneal Metastases A Phase 2 Randomized Clinical Trial

Autor: Arjen J. Witkamp, Joost Nederend, Andreas J A Bremers, Philip R. de Reuver, Wilhelmina M U van Grevenstein, Henk M.W. Verheul, Koen P. Rovers, Max J. Lahaye, Niels F. M. Kok, Jurriaan B. Tuynman, Checca Bakkers, Maartje Los, Ignace H. J. T. de Hingh, Anna M.J. Thijs, Patrick H. J. Hemmer, Alexandra R. M. Brandt-Kerkhof, Miriam Koopman, Onno Kranenburg, Petur Snaebjornsson, Marcel G. W. Dijkgraaf, Simon W. Nienhuijs, Arend G. J. Aalbers, Schelto Kruijff, Jacobus W. A. Burger, Tineke E. Buffart, Derk Jan A. de Groot, Esther van Meerten, Iris van 't Erve, Geert-Jan Creemers, Miranda Kusters, Pieter J. Tanis, Eva V. E. Madsen, Remond J.A. Fijneman, Kathelijn S. Versteeg, Djamila Boerma, Cornelis J A Punt, Marinus J. Wiezer

Publikováno v: Rovers, K P, Bakkers, C, Nienhuijs, S W, Burger, J W A, Creemers, G-J M, Thijs, A M J, Brandt-Kerkhof, A R M, Madsen, E V E, van Meerten, E, Tuynman, J B, Kusters, M, Versteeg, K S, Aalbers, A G J, Kok, N F M, Buffart, T E, Wiezer, M J, Boerma, D, Los, M, de Reuver, P R, Bremers, A J A, Verheul, H M W, Kruijff, S, de Groot, D J A, Witkamp, A J, van Grevenstein, W M U, Koopman, M, Nederend, J, Lahaye, M J, Kranenburg, O, Fijneman, R J A, van 't Erve, I, Snaebjornsson, P, Hemmer, P H J, Dijkgraaf, M G W, Punt, C J A, Tanis, P J & de Hingh, I H J T 2021, ' Perioperative systemic therapy vs cytoreductive surgery and hyperthermic intraperitoneal chemotherapy alone for resectable colorectal peritoneal metastases: A phase 2 randomized clinical trial ', JAMA Surgery, vol. 156, no. 8, pp. 710-720 . https://doi.org/10.1001/jamasurg.2021.1642
JAMA Surgery, 156(8), 710-720. American Medical Association
JAMA surgery, 156(8), 710-720. American Medical Association
JAMA Surgery, 156(8), 710-720. AMER MEDICAL ASSOC
JAMA Surgery, 156, 710-720
JAMA Surg
JAMA Surgery, 156, 8, pp. 710-720

Contains fulltext : 238268.pdf (Publisher’s version ) (Closed access) IMPORTANCE: To date, no randomized clinical trials have investigated perioperative systemic therapy relative to cytoreductive surgery and hyperthermic intraperitoneal chemotherap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::375b682e7bd1c0c6ebfa96df3e48e33e
https://hdl.handle.net/11370/c9e531bb-9f62-460d-afc2-636baf20eec6

Fertility-sparing surgery for patients with malignant ovarian germ cell tumors: 10 years of clinical experience from a tertiary referral center

Autor: Mislav Mikuš, Velena Radošević, Mario Ćorić, Pavao Planinić, Goran Vujić, Nikolina Benco, Tomislav Puževski, Helena Lovrić, Luka Matak, Mirna Bajt

Purpose: To describe a case series of patients with malignant ovarian germ cell tumors (MOGCT) treated exclusively with fertility-sparing surgery (FSS) with or without adjuvant chemotherapy. ----- Methods: We retrospectively reviewed the records of 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88cc3ff8176491ef67f496135f2ba46e
https://www.bib.irb.hr/1139186

Perioperative systemic therapy and cytoreductive surgery with HIPEC versus upfront cytoreductive surgery with HIPEC alone for isolated resectable colorectal peritoneal metastases: Protocol of a multicentre, open-label, parralel-group, phase II-III, randomised, superiority study (CAIRO6)

Autor: Koen P. Rovers, Checca Bakkers, Geert A. A. M. Simkens, Jacobus W. A. Burger, Simon W. Nienhuijs, Geert-Jan M. Creemers, Anna M. J. Thijs, Alexandra R. M. Brandt-Kerkhof, Eva V. E. Madsen, Ninos Ayez, Nadine L. de Boer, Esther van Meerten, Jurriaan B. Tuynman, Miranda Kusters, Nina R. Sluiter, Henk M. W. Verheul, Hans J. van der Vliet, Marinus J. Wiezer, Djamila Boerma, Emma C. E. Wassenaar, Maartje Los, Cornelis B. Hunting, Arend G. J. Aalbers, Niels F. M. Kok, Koert F. D. Kuhlmann, Henk Boot, Myriam Chalabi, Schelto Kruijff, Lukas B. Been, Robert J. van Ginkel, Derk Jan A. de Groot, Rudolf S. N. Fehrmann, Johannes H. W. de Wilt, Andreas J. A. Bremers, Philip R. de Reuver, Sandra A. Radema, Karin H. Herbschleb, Wilhelmina M. U. van Grevenstein, Arjen J. Witkamp, Miriam Koopman, Nadia Haj Mohammad, Eino B. van Duyn, Walter J. B. Mastboom, Leonie J. M. Mekenkamp, Joost Nederend, Max J. Lahaye, Petur Snaebjornsson, Cornelis Verhoef, Hanneke W. M. van Laarhoven, Aeilko H. Zwinderman, Jeanette M. Bouma, Onno Kranenburg, Iris van ‘t Erve, Remond J. A. Fijneman, Marcel G. W. Dijkgraaf, Patrick H. J. Hemmer, Cornelis J. A. Punt, Pieter J. Tanis, Ignace H. J. T. de Hingh, Dutch Peritoneal Oncology Group (DPOG), Dutch Colorectal Cancer Group (DCCG)

Publikováno v: BMC Cancer, 19
BMC cancer, 19(1):390. BioMed Central
BMC Cancer, 19(1). BioMed Central
Rovers, K P, Bakkers, C, Simkens, G A A M, Burger, J W A, Nienhuijs, S W, Creemers, G-J M, Thijs, A M J, Brandt-Kerkhof, A R M, Madsen, E V E, Ayez, N, de Boer, N L, van Meerten, E, Tuynman, J B, Kusters, M, Sluiter, N R, Verheul, H M W, van der Vliet, H J, Wiezer, M J, Boerma, D, Wassenaar, E C E, Los, M, Hunting, C B, Aalbers, A G J, Kok, N F M, Kuhlmann, K F D, Boot, H, Chalabi, M, Kruijff, S, Been, L B, van Ginkel, R J, de Groot, D J A, Fehrmann, R S N, de Wilt, J H W, Bremers, A J A, de Reuver, P R, Radema, S A, Herbschleb, K H, van Grevenstein, W M U, Witkamp, A J, Koopman, M, Haj Mohammad, N, van Duyn, E B, Mastboom, W J B, Mekenkamp, L J M, Nederend, J, Lahaye, M J, Snaebjornsson, P, Verhoef, C, van Laarhoven, H W M, Zwinderman, A H, Bouma, J M, Kranenburg, O, van 't Erve, I, Fijneman, R J A, Dijkgraaf, M G W, Hemmer, P H J, Punt, C J A, Tanis, P J & de Hingh, I H J T 2019, ' Perioperative systemic therapy and cytoreductive surgery with HIPEC versus upfront cytoreductive surgery with HIPEC alone for isolated resectable colorectal peritoneal metastases: Protocol of a multicentre, open-label, parralel-group, phase II-III, randomised, superiority study (CAIRO6) ', BMC Cancer, vol. 19, no. 1, 390 . https://doi.org/10.1186/s12885-019-5545-0
BMC Cancer, 19:390. BioMed Central Ltd.
BMC Cancer, 19:390. BMC
BMC Cancer, 19(1):390. BioMed Central
BMC Cancer, Vol 19, Iss 1, Pp 1-15 (2019)

Background Upfront cytoreductive surgery with HIPEC (CRS-HIPEC) is the standard treatment for isolated resectable colorectal peritoneal metastases (PM) in the Netherlands. This study investigates whether addition of perioperative systemic therapy to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::410235f4855c4dd4392ec44a9e7244ce
https://doi.org/10.1186/s12885-019-5545-0

Omission of doxorubicin from the treatment of stage II-III, intermediate-risk Wilms' tumour (SIOP WT 2001): an open-label, non-inferiority, randomised controlled trial

Autor: Kathryn Pritchard-Jones, Anne-Sophie DEFACHELLES, Sucheta Vaidya, Gustaf Ljungman, Norbert Graf, Marc Ansari, Gordan Vujanic, Ricardo López Almaraz, Pedro Zubizarreta, Jan Godziński, Pamela Kearns, Anna Llort, Beatriz De Camargo, Leo Kager, Harm Van Tinteren, Ingrid Øra

Publikováno v: Pritchard-Jones, K, Bergeron, C, de Camargo, B, van den Heuvel-Eibrink, M M, Acha, T, Godzinski, J, Oldenburger, F, Boccon-Gibod, L, Leuschner, I, Vujanic, G, Sandstedt, B, de Kraker, J, van Tinteren, H, Graf, N & SIOP Renal Tumours Study Group 2015, ' Omission of doxorubicin from the treatment of stage II-III, intermediate-risk Wilms' tumour (SIOP WT 2001) : an open-label, non-inferiority, randomised controlled trial ', Lancet, vol. 386, no. 9999, pp. 1156-1164 . https://doi.org/10.1016/S0140-6736(14)62395-3
Lancet, 386(9999), 1156-1164. Elsevier Limited
The Lancet, Vol. 386, No 9999 (2015) pp. 1156-64

BACKGROUND: Before this study started, the standard postoperative chemotherapy regimen for stage II-III Wilms' tumour pretreated with chemotherapy was to include doxorubicin. However, avoidance of doxorubicin-related cardiotoxicity effects is importa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05386b33380bcd2146bacb31bab8c77a
https://doi.org/10.1016/s0140-6736(14)62395-3

Pegfilgrastim Administered on the Same Day with Dose-Dense Adjuvant Chemotherapy for Breast Cancer Is Associated with a Higher Incidence of Febrile Neutropenia as Compared to Conventional Growth Factor Support: Matched Case-Control Study of the Hellenic Cooperative Oncology Group

Autor: Epaminondas Samantas, Gerasimos Aravantinos, George Fountzilas, Ioannis Xanthakis, Dimosthenis Skarlos, George Pentheroudakis, Eleni Galani, Irene Grimani, Dimitrios Pectasides, Evangelos Lianos, Eleni Timotheadou

Publikováno v: Oncology. 77:107-112

Objective: Recombinant human granulocyte-colony-stimulating factors such as filgrastim and pegfilgrastim have been employed as primary and secondary prophylaxis against neutropenia in cancer patients receiving chemotherapy. This study was conducted t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74cf5d61aed71285391a7352e1d43462
https://doi.org/10.1159/000229504