Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Chemokine receptor binding"'
Autor:
Jinxia Feng, Weigan Xu, Chunming Xie, Qiaohua Hu, Xiangxia Zeng, Jinlun Hu, Mei Yan, Yue Fu, Zi Cong Gu
Publikováno v:
Aging. 13:22792-22801
Objective: Paraquat (N,N0-dimethyl-4,40-bipyridinium dichloride;PQ) is a highly toxic pesticide, which usually leads to acute lung injury and subsequent development of pulmonary fibrosis. The exact mechanism underlying PQ-induced lung fibrosis remain
Publikováno v:
Mathematical Biosciences and Engineering, Vol 18, Iss 6, Pp 8201-8222 (2021)
Cervical cancer, as the second most common female malignancy, brings a great health burden to women worldwide. Cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC) are the most common histological subtypes of cervical cancer. CXC c
Autor:
Qingzhou Huang, Yu Zhao, Bowen Li, Hanwei Jiao, Cailiang Fan, Baoru Han, Li Wu, Xuehong Shuai, Wenjie Li, Guojing Gu, Chen Jixuan, Zhixiong Zhou, Juan Liu, Yichen Luo, Jianjun Wen
Publikováno v:
Innate Immunity. 26:635-648
As the molecular mechanisms of Brucella ovis pathogenicity are not completely clear, we have applied a transcriptome approach to identify the differentially expressed genes (DEGs) in RAW264.7 macrophage infected with B. ovis. The DEGs related to immu
Publikováno v:
International Journal of General Medicine
Xiuyun Xuan,1 Yuqi Wang,2 Yanhong Sun,3 Changzheng Huang1 1Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, Peopleâs Republic of China; 2Department of Radiolo
Publikováno v:
Shock. 51:770-779
Long noncoding RNAs (lncRNAs), once thought to be transcriptional noise, have been recently shown to regulate a variety of biological processes. However, their roles in the inflammatory response are largely unexplored. In this study, we performed hig
Identification of key genes and pathways involved in microsatellite instability in colorectal cancer
Publikováno v:
Molecular Medicine Reports
Microsatellite instability (MSI) has emerged as one of the key biological features of colorectal cancer (CRC). However, controversies remain regarding the association between the MSI status and clinicopathological characteristics of CRC. Therefore, i
Autor:
Martijn P. Bemelmans, Natalia V. Ortiz Zacarías, Karin E. de Visser, Tracy M. Handel, Laura H. Heitman
Publikováno v:
Trends in Pharmacological Sciences
The chemokine system, comprising 48 chemokines and 23 receptors, is critically involved in several hallmarks of cancer. Yet, despite extensive efforts from the pharmaceutical sector, only two drugs aimed at this system are currently approved for clin
Publikováno v:
Cancer Cell International
Cancer Cell International, Vol 19, Iss 1, Pp 1-17 (2019)
Cancer Cell International, Vol 19, Iss 1, Pp 1-17 (2019)
Background Endometrial cancer (EC) is one of the female malignant tumors. Endometrial cancer predominately affects post-menopausal women. Bioinformatics analysis has been widely applied to screen and analyze genes in linkage to various types of cance
Autor:
Zhijian Wei, Bin Pan, Hengxing Zhou, Xiaohong Kong, Lu Lu, Zhongju Shi, Li Xueying, Liu Jun, Lu Liu, Yao Wang, Shiqing Feng, Yi Kang
Publikováno v:
Gene. 661:119-125
Spinal cord injury (SCI) is a serious devastating condition and it has a high mortality rate and morbidity rate. The early pathological changes in the immediate phase of SCI may play a major part in the development of secondary injury. Alterations in
Autor:
Etsuko Toda, Tatsuichiro Tsuji, Kouji Matsushima, Kaori Yunoki, Akihiro Sonoda, Yuya Terashima, Sosuke Yoshinaga, Norihito Ishida, Hiroaki Terasawa, Mitsuhiro Takeda
Publikováno v:
Biomolecular NMR Assignments. 12:259-262
FROUNT is a cytoplasmic protein that interacts with the membrane-proximal C-terminal regions (Pro-Cs) of the CCR2 and CCR5 chemokine receptors. The interactions between FROUNT and the chemokine receptors play an important role in the migration of inf