Attenuation of the pro-inflammatory signature of lung cancer-derived mesenchymal stromal cells by statins

Autor: Ivan Stamenkovic, Giulia Fregni, Sabine Galland, Patricia Martin, Igor Letovanec

Publikováno v: Cancer letters, vol. 484, pp. 50-64

Solid tumor growth triggers a dynamic host response, which recapitulates wound healing and defines the tumor microenvironment (TME). In addition to the action of the tumor cells themselves, the TME is maintained by a myriad of immune and stromal cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46d4c526f18540dbdc86599d3242ed3f
https://doi.org/10.1016/j.canlet.2020.05.005

Impact of carbohydrate restriction in the context of obesity on prostate tumor growth in the Hi-Myc transgenic mouse model

Autor: Everardo Macias, Stephen D. Hursting, Sergio Sanders, George Thomas, Beatrice S. Knudsen, Stephen J. Freedland, Emma H. Allott

Publikováno v: Prostate cancer and prostatic diseases
Allott, E H, Macias, E, Sanders, S, Knudsen, B S, Thomas, G V, Hursting, S D & Freedland, S J 2017, ' Impact of carbohydrate restriction in the context of obesity on prostate tumor growth in the Hi-Myc transgenic mouse model ', Prostate cancer and prostatic diseases, vol. 20, no. 2, pp. 165-171 . https://doi.org/10.1038/pcan.2016.73

BACKGROUND: Previously, we showed that carbohydrate restriction with calorie restriction slowed tumor growth in xenograft mouse prostate cancer models. Herein, we examined the impact of carbohydrate restriction without calorie restriction on tumor de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82cfe76e691b2e3756eaf32094364937
https://doi.org/10.1038/pcan.2016.73

Experimental demyelination and axonal loss are reduced in MicroRNA-146a deficient mice

Autor: Nellie A. Martin, Viktor Molnar, Gabor T. Szilagyi, Maria L. Elkjaer, Arkadiusz Nawrocki, Justyna Okarmus, Agnieszka Wlodarczyk, Eva K. Thygesen, Miklos Palkovits, Ferenc Gallyas, Martin R. Larsen, Hans Lassmann, Eirikur Benedikz, Trevor Owens, Asa F. Svenningsen, Zsolt Illes

Publikováno v: Martin, N A, Molnar, V, Szilagyi, G T, Elkjaer, M L, Nawrocki, A, Okarmus, J, Wlodarczyk, A, Thygesen, E K, Palkovits, M, Gallyas, F, Larsen, M R, Lassmann, H, Benedikz, E, Owens, T, Svenningsen, A F & Illes, Z 2018, ' Experimental demyelination and axonal loss are reduced in MicroRNA-146a deficient mice ', Frontiers in Immunology, vol. 9, 490 . https://doi.org/10.3389/fimmu.2018.00490
Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2018)

Background: The cuprizone (CPZ) model of multiple sclerosis (MS) was used to identify microRNAs (miRNAs) related to in vivo de- and remyelination. We further investigated the role of miR-146a in miR-146a-deficient (KO) mice: this miRNA is differentia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd4045fbbca3098e261b35feccb0ac8f
https://findresearcher.sdu.dk:8443/ws/files/137639610/Experimental_demyelination_and_axonal_loss_are_reduced_in_MicroRNA_146a_deficient_mice.pdf

Blockade of vascular adhesion protein-1 attenuates choroidal neovascularization

Autor: Yoshikawa, Nami, Noda, Kousuke, Ozawa, Yoko, Tsubota, Kazuo, Mashima, Yukihiko, Ishida, Susumu

Publikováno v: Molecular vision. 18:593-600

Purpose: Vascular adhesion protein (VAP)-1 is an adhesion molecule elucidated as a mediator of the leukocyte recruitment cascade. The purpose of this study was to investigate the role of VAP-1 in ocular inflammatory neovascularization using a mouse l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=jairo_______::dbd91fc75e6eeb53447d1920c1ae3a4b
http://hdl.handle.net/2115/54617