Zobrazeno 1 - 10
of 1 353
pro vyhledávání: '"Chemo resistance"'
Autor:
Pratham Phadte, Aniketh Bishnu, Pranay Dey, Manikandan M, Megha Mehrotra, Prerna Singh, Shritama Chakrabarty, Rounak Majumdar, Bharat Rekhi, Malay Patra, Abhijit De, Pritha Ray
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-23 (2024)
Abstract Background The mechanisms enabling dynamic shifts between drug-resistant and drug-sensitive states in cancer cells are still underexplored. This study investigated the role of targeted autophagic protein degradation in regulating ovarian can
Externí odkaz:
https://doaj.org/article/b30acfb5696144008e3ac1ccbfe7940d
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-12 (2024)
Abstract Glioblastoma (GBM) is an aggressive nervous system tumor with a poor prognosis. Although, surgery, radiation therapy, and chemotherapy are the current standard protocol for GBM patients, there is still a poor prognosis in these patients. Tem
Externí odkaz:
https://doaj.org/article/e123670604444fc0b41f40537ce05f1d
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-12 (2024)
Abstract The developments of antibodies for cancer therapeutics have made remarkable success in recent years. There are multiple factors contributing to the success of the biological molecule including origin of the antibody, isotype, affinity, avidi
Externí odkaz:
https://doaj.org/article/5de5101015f34a49ae5a65c127553bf6
Publikováno v:
Translational Oncology, Vol 49, Iss , Pp 102082- (2024)
Background: The mechanisms by which SLC2A1 enhances chemo-resistance of taxanes to non-small cell lung cancer (NSCLC) remains enigmatic. Methods: An investigation into the SLC2A1 expression pattern and prognosis across diverse datasets, as well as ou
Externí odkaz:
https://doaj.org/article/8b0557d6540b4f66b7d85dfac60901f7
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Bladder cancer (BC) is the sixth most common worldwide urologic malignancy associated with elevated morbidity and mortality rates if not well treated. The muscle-invasive form of BC develops in about 25% of patients. Moreover, according to e
Externí odkaz:
https://doaj.org/article/9aaa281ffe95463cb297cc1d2f458ee2
Autor:
Mona Tangsiri, Ali Hheidari, Mahsa Liaghat, Mahtab Razlansari, Narges Ebrahimi, Abdullatif Akbari, Seyed Mostafa Noorbakhsh Varnosfaderani, Fahimeh Maleki-Sheikhabadi, Ali Norouzi, Maryam Bakhtiyari, Hamidreza Zalpoor, Mohsen Nabi-Afjadi, Abbas Rahdar
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 170, Iss , Pp 115973- (2024)
The resistance of cancer cells to chemotherapy, also known as chemo-resistance, poses a significant obstacle to cancer treatment and can ultimately result in patient mortality. Epithelial-mesenchymal transition (EMT) is one of the many factors and pr
Externí odkaz:
https://doaj.org/article/934cf7451d754f6a9e7d5161aa16d88f
Autor:
Hao Jiang, Hailong Tian, Zhihan Wang, Bowen Li, Rui Chen, Kangjia Luo, Shuaijun Lu, Edouard C. Nice, Wei Zhang, Canhua Huang, Yuping Zhou, Shaojiang Zheng, Feng Gao
Publikováno v:
Biomaterials Research, Vol 27, Iss 1, Pp 1-20 (2023)
Abstract Background Colorectal cancer (CRC) is the second most deadly cancer worldwide, with chemo-resistance remaining a major obstacle in CRC treatment. Notably, the imbalance of redox homeostasis-mediated ferroptosis and the modulation of hypoxic
Externí odkaz:
https://doaj.org/article/c14bf3e5444b4384a06e80ef2fd70865
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Chemotherapy is widely used as one of the first line therapeutic methods in cancer patients. However, chemotherapeutic resistance is one of the most common problems in cancer patients, which leads to the therapeutic failure and tumor relapse
Externí odkaz:
https://doaj.org/article/ec9b347d05194c67bb4eb286a2059587
Autor:
Atefeh Khodakarami, Mahsa Afsari Kashani, Atefeh Nazer, Armin Mahmoudsalehi Kheshti, Bentolhoda Rashidi, Vahid Karpisheh, Ali Masjedi, Shiva Abolhasani, Sepideh Izadi, Rafieh Bagherifar, Seyyed Sina Hejazian, Hamed Mohammadi, AliAkbar Movassaghpour, Abbas Ali Hosseinpour Feizi, Mohammad Hojjat-Farsangi, Farhad Jadidi-Niaragh
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background Targeting influential factors in resistance to chemotherapy is one way to increase the effectiveness of chemotherapeutics. The nuclear factor erythroid 2-related factor 2 (Nrf2) pathway overexpresses in chronic lymphocytic leukemi
Externí odkaz:
https://doaj.org/article/84bb4d6d12e846eaad43995f13b52c41
Autor:
Amirhosein Maharati, Meysam Moghbeli
Publikováno v:
Cell Division, Vol 18, Iss 1, Pp 1-13 (2023)
Abstract Lung cancer as the leading cause of cancer related mortality is always one of the main global health challenges. Despite the recent progresses in therapeutic methods, the mortality rate is still significantly high among lung cancer patients.
Externí odkaz:
https://doaj.org/article/f0d905a7fbd44197bd0932437d49768d