Zobrazeno 1 - 10
of 1 361
pro vyhledávání: '"Chemo immunotherapy"'
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 9, Pp 4087-4101 (2024)
Currently, the efficacy of albumin-bound paclitaxel (PTX@Alb) is still limited due to the impaired PTX@Alb accumulation in tumors partly mediated by the dense collagen distribution. Meanwhile, acquired immune resistance always occurs due to the enhan
Externí odkaz:
https://doaj.org/article/f200490f693346e19087c3bb3f423f12
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract This study aimed to explore potential radiomics biomarkers in predicting the efficiency of chemo-immunotherapy in patients with advanced non-small cell lung cancer (NSCLC). Eligible patients were prospectively assigned to receive chemo-immun
Externí odkaz:
https://doaj.org/article/490c34db81dd4bcb8bd2aae3a56b1e93
Publikováno v:
Materials & Design, Vol 247, Iss , Pp 113406- (2024)
Lung cancer is the most leading cause of cancer death. Traditional chemotherapy has unavoidable drawbacks of nonspecific tumor targeting, high toxicity, and poor therapeutic efficiency. Nanocarriers can achieve accurate delivery and reduce adverse re
Externí odkaz:
https://doaj.org/article/659d4a075d7849b0960d905bd532d021
Publikováno v:
The Clinical Respiratory Journal, Vol 18, Iss 10, Pp n/a-n/a (2024)
ABSTRACT Background Osimertinib is approved as a standard treatment for non‐small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutation by FDA. However, the mechanisms of resistance for nearly half of patients afte
Externí odkaz:
https://doaj.org/article/606cde5531c64626ba7ac7fc48105468
Autor:
Renming Fan, Ruizhuo Lin, Shuo Zhang, Aohua Deng, Yongrui Hai, Junyan Zhuang, Yang Liu, Maosheng Cheng, Gaofei Wei
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 4, Pp 1742-1758 (2024)
Mitochondrial membrane remodeling can trigger the release of mitochondrial DNA (mtDNA), leading to the activation of cellular oxidative stress and immune responses. While the role of mitochondrial membrane remodeling in promoting inflammation in hepa
Externí odkaz:
https://doaj.org/article/2246674c496b4cbdaf7c70db58d65f07
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundAdvanced non-small cell lung cancer (NSCLC) presents significant treatment challenges, with chemo-immunotherapy emerging as a promising approach. This study explores the potential of lipidomic biomarkers to predict responses to chemo-immuno
Externí odkaz:
https://doaj.org/article/a63015a9ac674cf5b026aaae3e76e281
Autor:
Arter ZL, Nagasaka M
Publikováno v:
Lung Cancer: Targets and Therapy, Vol Volume 15, Pp 1-8 (2024)
Zhaohui Liao Arter,1,2 Misako Nagasaka1– 3 1Department of Medicine, Division of Hematology-Oncology, University of California Irvine School of Medicine, Orange, CA, USA; 2Chao Family Comprehensive Cancer Center, Orange, CA, USA; 3Department of Medi
Externí odkaz:
https://doaj.org/article/d242ce60864c4f78b2cb741f8d0f4fb4
Publikováno v:
Bioactive Materials, Vol 31, Iss , Pp 549-562 (2024)
Herein, we designed Comp. 1 to simultaneously respond to two enzymes: alkaline phosphatase and matrix metalloproteinase 2, which is commonly found in highly malignant cancer cell lines containing B16–F10 murine melanoma cells and CT26 murine colon
Externí odkaz:
https://doaj.org/article/22dcfe90603d47e9a2cededcc3eb8562
Publikováno v:
Translational Oncology, Vol 44, Iss , Pp 101944- (2024)
In the pursuit of advancing cancer therapy, this study explores the predictive power of machine learning in analyzing tumor characteristics, specifically focusing on the effects of tumor stiffness and perfusion (i.e., blood flow) on treatment efficac
Externí odkaz:
https://doaj.org/article/d10010e0cf5045aabc75ba887fbe7949
Publikováno v:
Advanced Science, Vol 11, Iss 17, Pp n/a-n/a (2024)
Abstract Molecular engineering of drug delivering platforms to provide collaborative biological effects with loaded drugs is of great medical significance. Herein, cannabinoid receptor 1 (CB1)‐ and reactive oxygen species (ROS)‐targeting electros
Externí odkaz:
https://doaj.org/article/31f37af03738441fa99f70a69002d68a