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Critical assessment of protein intrinsic disorder prediction

Autor: Necci, Marco, Piovesan, Damiano, Hoque Md, Tamjidul, Walsh, Ian, Iqbal, Sumaiya, Vendruscolo, Michele, Sormanni, Pietro, Wang, Chen, Raimondi, Daniele, Sharma, Ronesh, Zhou, Yaoqi, Litfin, Thomas, Galzitskaya Oxana, Valerianovna, Lobanov Michail, Yu, Vranken, Wim, Wallner, Björn, Mirabello, Claudio, Malhis, Nawar, Dosztányi, Zsuzsanna, Erdős, Gábor, Mészáros, Bálint, Gao, Jianzhao, Wang, Kui, Hu, Gang, Wu, Zhonghua, Sharma, Alok, Hanson, Jack, Paliwal, Kuldip, Callebaut, Isabelle, Bitard-Feildel, Tristan, Orlando, Gabriele, Peng, Zhenling, Xu, Jinbo, Wang, Sheng, Jones David, T., Cozzetto, Domenico, Meng, Fanchi, Yan, Jing, Gsponer, Jörg, Cheng, Jianlin, Wu, Tianqi, Kurgan, Lukasz, Promponas Vasilis, J., Tamana, Stella, Marino-Buslje, Cristina, Martínez-Pérez, Elizabeth, Chasapi, Anastasia, Ouzounis, Christos, Dunker A., Keith, Kajava Andrey, V., Leclercq Jeremy, Y., Aykac-Fas, Burcu, Lambrughi, Matteo, Maiani, Emiliano, Papaleo, Elena, Chemes Lucia, Beatriz, Álvarez, Lucía, González-Foutel Nicolás, S., Iglesias, Valentin, Pujols, Jordi, Ventura, Salvador, Palopoli, Nicolás, Benítez Guillermo, Ignacio, Parisi, Gustavo, Bassot, Claudio, Elofsson, Arne, Govindarajan, Sudha, Lamb, John, Salvatore, Marco, Hatos, András, Monzon Alexander, Miguel, Bevilacqua, Martina, Mičetić, Ivan, Minervini, Giovanni, Paladin, Lisanna, Quaglia, Federica, Leonardi, Emanuela, Davey, Norman, Horvath, Tamas, Kovacs Orsolya, Panna, Murvai, Nikoletta, Pancsa, Rita, Schad, Eva, Szabo, Beata, Tantos, Agnes, Macedo-Ribeiro, Sandra, Manso Jose, Antonio, Pereira Pedro José, Barbosa, Davidović, Radoslav, Veljkovic, Nevena, Hajdu-Soltész, Borbála, Pajkos, Mátyás, Szaniszló, Tamás, Guharoy, Mainak, Lazar, Tamas, Macossay-Castillo, Mauricio, Tompa, Peter, Tosatto Silvio C., E., Caid, Predictors, DisProt, Curators

Publikováno v: Nature Methods
Nature Methods, 2021, 18 (5), pp.472-481. ⟨10.1038/s41592-021-01117-3⟩
Nature Methods, Nature Publishing Group, 2021, ⟨10.1038/s41592-021-01117-3⟩
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Nature Methods, 2021, ⟨10.1038/s41592-021-01117-3⟩
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Nature Methods, Nature Publishing Group, 2021, 18 (5), pp.472-481. ⟨10.1038/s41592-021-01117-3⟩

Intrinsically disordered proteins, defying the traditional protein structure–function paradigm, are a challenge to study experimentally. Because a large part of our knowledge rests on computational predictions, it is crucial that their accuracy is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::038090046479130e4d0ff797fc08550f
https://hal.sorbonne-universite.fr/hal-03329755/document

Circular Dichroism Techniques for the identification of Intrinsically Disordered Proteins

Autor: Chemes, Lucia Beatriz, Alonso, Leonardo Gabriel, Noval, María Gabriela, de Prat Gay, Gonzalo

Circular dichroism (CD) spectroscopy is a simple and powerful technique, which allows for the assessment of the conformational properties of a protein or protein domain. Intrinsically disordered proteins (IDPs), as discussed throughout this series, d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3498::7d5dbf327ef230bd349ba1bf9f509e79
https://link.springer.com/protocol/10.1007/978-1-61779-927-3_22

Predicting the effect of disordered linkers on effective concentrations and avidity with the "C eff calculator" app.

Autor: Kjaergaard M; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark; The Danish Research Institute for Translational Neuroscience (DANDRITE), Aarhus, Denmark; Center for Proteins in Memory (PROMEMO), Aarhus, Denmark. Electronic address: magnus@mbg.au.dk., Glavina J; Instituto de Investigaciones Biotecnológicas 'Dr. Rodolfo A. Ugalde', IIB-UNSAM, IIBIO-CONICET, Universidad Nacional de San Martín, San Martín, Argentina., Chemes LB; Instituto de Investigaciones Biotecnológicas 'Dr. Rodolfo A. Ugalde', IIB-UNSAM, IIBIO-CONICET, Universidad Nacional de San Martín, San Martín, Argentina. Electronic address: lchemes@iib.unsam.edu.ar.

Publikováno v: Methods in enzymology [Methods Enzymol] 2021; Vol. 647, pp. 145-171. Date of Electronic Publication: 2020 Nov 13.