A low-cost, paper-based hybrid capture assay to detect high-risk HPV DNA for cervical cancer screening in low-resource settings

Autor: Chelsey A. Smith, Megan M. Chang, Kathryn A. Kundrod, Emilie N. Novak, Sonia G. Parra, Leticia López, Celda Mavume, Cesaltina Lorenzoni, Mauricio Maza, Mila P. Salcedo, Jennifer L. Carns, Ellen Baker, Jane Montealegre, Michael Scheurer, Philip E. Castle, Kathleen M. Schmeler, Rebecca R. Richards-Kortum

Publikováno v: Lab on a Chip. 23:451-465

Cervical cancer is a leading cause of cancer death for women in low-resource settings. The World Health Organization recommends that cervical cancer screening programs incorporate HPV DNA testing, but available tests are expensive, require laboratory

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::046c676a6732c26b64f5490740084b45
https://doi.org/10.1039/d2lc00885h

Development of Low-Cost Point-of-Care Technologies for Cervical Cancer Prevention Based on a Single-Board Computer

Autor: Chelsey A. Smith, Mauricio Maza, Sonia G. Parra, Eduardo Carranza, Brady Hunt, Kathleen M. Schmeler, Jackson Coole, Rebecca Richards-Kortum, Pelham Keahey

Publikováno v: IEEE Journal of Translational Engineering in Health and Medicine, Vol 8, Pp 1-10 (2020)
IEEE Journal of Translational Engineering in Health and Medicine

Cervical cancer disproportionally affects women in low- and middle-income countries, in part due to the difficulty of implementing existing cervical cancer screening and diagnostic technologies in low-resource settings. Single-board computers offer a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b4818947465a4388cc8de7a48d47221
https://ieeexplore.ieee.org/document/8978694/

Association of SLCO 1B1 *14 Allele with Poor Response to Methotrexate in Juvenile Idiopathic Arthritis Patients

Autor: Susan D. Thompson, Mara L. Becker, Carl D. Langefeld, Chelsey N. Smith, Miranda C. Marion, Halima Moncrieffe, Laura B. Ramsey, Marc Sudman

Publikováno v: ACR Open Rheumatology. 1:58-62

Objective Variants in the SLCO1B1 gene, encoding a hepatic methotrexate (MTX) transporter, affect clearance of high-dose MTX. We tested whether in the *14 and *15 alleles of SLCO1B1 influenced the response to low-dose MTX in juvenile idiopathic arthr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c7765291429c6a80166d25fab73ffddc
https://doi.org/10.1002/acr2.1008

Reverse transcription loop-mediated isothermal amplification (RT-LAMP) for point-of-care detection of SARS-CoV-2: a clinical study to evaluate agreement with RT-qPCR

Autor: Chelsey A. Smith, Keyur P. Patel, Mary E. Natoli, Rebecca Richards-Kortum, Kathleen M. Schmeler, Sai Paul, Megan Chang, Karen Eldin, Kathryn Kundrod, Ellen Baker

Publikováno v: The Lancet. Global Health
The Lancet Global Health, Vol 9, Iss, Pp S3-(2021)

Background: The global COVID-19 pandemic caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has highlighted the need for rapid, accurate, and accessible diagnostics to enable timely treatment and outbreak control. Howeve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee4a614ffe787b319a8fd90c88c11680
http://europepmc.org/articles/PMC7952100

Modeling the natural history of Pelizaeus–Merzbacher disease

Autor: Joshua A. Mayer, Ian D. Duncan, Elizabeth Cooksey, Abigail B. Radcliff, Ian R. Griffiths, Chelsey M. Smith, James E. Goldman

Publikováno v: Neurobiology of Disease, Vol 75, Iss, Pp 115-130 (2015)

Major gaps in our understanding of the leukodystrophies result from their rarity and the lack of tissue for the interdisciplinary studies required to extend our knowledge of the pathophysiology of the diseases. This study details the natural evolutio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b130a47c212ce5b8f645ab61a0decb54
http://www.sciencedirect.com/science/article/pii/S0969996114003945