Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Chelsee Hewitt"'
Autor:
Maarten J. IJzerman, Jasper de Boer, Arun Azad, Koen Degeling, Joel Geoghegan, Chelsee Hewitt, Frédéric Hollande, Belinda Lee, Yat Ho To, Richard W. Tothill, Gavin Wright, Jeanne Tie, Sarah-Jane Dawson
Publikováno v:
Diagnostics, Vol 11, Iss 1, p 103 (2021)
Blood-based liquid biopsies are considered a new and promising diagnostic and monitoring tool for cancer. As liquid biopsies only require a blood draw, they are non-invasive, potentially more rapid and assumed to be a less costly alternative to genom
Externí odkaz:
https://doaj.org/article/0cfa62b0fdea4a478afe42a86af7cbe7
Autor:
Gillian Mitchell, Mandy L Ballinger, Stephen Wong, Chelsee Hewitt, Paul James, Mary-Anne Young, Arcadi Cipponi, Tiffany Pang, David L Goode, Alex Dobrovic, David M Thomas, International Sarcoma Kindred Study
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69026 (2013)
Sarcomas are a key feature of Li-Fraumeni and related syndromes (LFS/LFL), associated with germline TP53 mutations. Current penetrance estimates for TP53 mutations are subject to significant ascertainment bias. The International Sarcoma Kindred Study
Externí odkaz:
https://doaj.org/article/f425bdcf908c4efeb2d912f309ba26f8
Autor:
Rainier Arnolda, Kerryn Howlett, Timmy Chan, Jeanette Raleigh, Athena Hatzimihalis, Anthony Bell, Andrew Fellowes, Shahneen Sandhu, Grant A. McArthur, Stephen B. Fox, Sarah-Jane Dawson, Chelsee Hewitt, Kate Jones, Stephen Q. Wong
Publikováno v:
Pathology. 54:772-778
Droplet digital PCR (ddPCR) has been demonstrated in many research studies to be a sensitive method in the analysis of circulating tumour DNA (ctDNA) for identifying mutations and tracking disease. The transition of ddPCR into the diagnostic setting
Autor:
Michael P. Flood, Anshini Jain, Catherine Mitchell, Chelsee Hewitt, Robert Ramsay, Michael Michael, Alexander G. Heriot, Jeanne Tie
Publikováno v:
European Journal of Surgical Oncology. 48:2218-2225
Stratification of patients with colorectal peritoneal metastases (CRPM) using RAS/BRAF mutational status may refine patient selection for cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). This study aimed to analyse t
Autor:
Rebecca Lee, Dominic G. Rothwell, Richard Jackson, Nigel Smith, Stephen Q Wong, Noel Kelso, George Burghel, Chelsee Hewitt, Harry Clarke, Jackie Mitchell, Kate Jones, Andrew Muinonen-Martin, Samra Turajlic, Philippa Gail Corrie, Richard Marais, Mark R. Middleton, Sarah-Jane Dawson, Shahneen Sandhu, Caroline Dive, Paul Lorigan
Publikováno v:
Journal of Clinical Oncology. 40:TPS9603-TPS9603
TPS9603 Background: Circulating tumor DNA (ctDNA; the tumor derived fraction of circulating free DNA in the blood) is a well recognized, minimally-invasive biomarker of tumor burden/progression in many cancers. We have previously shown in retrospecti
Autor:
Gary J. Macfarlane, Susanne M. Gollin, Edwina McGlinn, Chelsee Hewitt, Peter R. Wilson, Nalin Thakker, Kenneth K Parkinson, R.T.M. Woodwards, Ian C. Paterson, Anne Papageorgiou, Philip Sloan, Andrew P. Read
Publikováno v:
Cancer Letters. 209:207-213
Allelic imbalance on chromosome arm 8p is common in head and neck squamous cell carcinoma (HNSCC). DLC1, a tumour suppressor gene inactivated in liver carcinogenesis and encoding a Rho GTPase activating protein (RhoGAP) maps to one of the deleted reg
Autor:
D. McCormick, F. N. Hattab, Dušan Turk, Michael J. Dixon, Reza Yaghmai, Ethlin W. Jabs, Peter Brett, Gerry Linden, Chelsee Hewitt, Pedro Bullón, Igor Stern, I. R. Wallace, Mohamed Al-Hamed, Nalin Thakker, Jacqueline James, Melanie Wong, Richard P Widmer, Stefan G. Rüdiger, Philip Sloan, Carmel Toomes, Peter H. Hoeger, James E. Briggs, Oliver Bleck, Khaled Abdul Gaffar, Gregor J. Petersilka, Liqun Zhang, Lama Awawdeh, Rebecca Howard, Maurizio Battino, Louise Southern, Andrew P. Read
Publikováno v:
Human Mutation. 23:222-228
We have previously reported that loss-of-function mutations in the cathepsin C gene (CTSC) result in Papillon Lefevre syndrome, an autosomal recessive condition characterized by palmoplantar keratosis and early,onset, severe periodontitis. Others hav
Autor:
Jacqueline James, F. N. Hattab, Chelsee Hewitt, K. A. Ghaffar, Carmel Toomes, Chu Lee Wu, Nalin Thakker, W. Amin, Andrew P. Read, Philip Sloan
Publikováno v:
The British journal of dermatology. 151(6)
The co-occurrence of two rare recessive genetic conditions in apparently unrelated individuals or families is extremely rare. Two geographically distant and apparently unrelated families were identified in which individuals were simultaneously affect
Autor:
Chelsee, Hewitt, Derek, McCormick, Gerry, Linden, Dusan, Turk, Igor, Stern, Ian, Wallace, Louise, Southern, Liqun, Zhang, Rebecca, Howard, Pedro, Bullon, Melanie, Wong, Richard, Widmer, Khaled Abdul, Gaffar, Lama, Awawdeh, Jim, Briggs, Reza, Yaghmai, Ethlin W, Jabs, Peter, Hoeger, Oliver, Bleck, Stefan G, Rüdiger, Gregor, Petersilka, Maurizio, Battino, Peter, Brett, Faiez, Hattab, Mohamed, Al-Hamed, Philip, Sloan, Carmel, Toomes, Mike, Dixon, Jacqueline, James, Andrew P, Read, Nalin, Thakker
Publikováno v:
Human mutation. 23(3)
We have previously reported that loss-of-function mutations in the cathepsin C gene (CTSC) result in Papillon-Lefèvre syndrome, an autosomal recessive condition characterized by palmoplantar keratosis and early-onset, severe periodontitis. Others ha
Autor:
Robert G Elles, Chelsee Hewitt, Anthony Howell, Richard C.K. Jordan, Chu Lee Wu, Philip Sloan, Andrew P. Read, Nalin Thakker, D. Gareth Evans
Publikováno v:
Human molecular genetics. 11(11)
Familial melanoma predisposition is associated with germline mutations at the CDKN2A/ARF locus in up to 40% of families. The exact role of the two proteins encoded by this complex locus in this predisposition is unclear. Most mutations affect either