Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Chelsea Szu-Tu"'
Autor:
Sonia Jaramillo, Michael Scherer, Chelsea Szu-Tu, Sergi Beneyto-Calabuig, Carsten Müller-Tidow, Richard F. Schlenk, Michael Hundemer, Lars Velten, Caroline Pabst
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Not available.
Externí odkaz:
https://doaj.org/article/a19aac35889a4f3c86484832583752d9
Autor:
Lars Velten, Benjamin A. Story, Pablo Hernández-Malmierca, Simon Raffel, Daniel R. Leonce, Jennifer Milbank, Malte Paulsen, Aykut Demir, Chelsea Szu-Tu, Robert Frömel, Christoph Lutz, Daniel Nowak, Johann-Christoph Jann, Caroline Pabst, Tobias Boch, Wolf-Karsten Hofmann, Carsten Müller-Tidow, Andreas Trumpp, Simon Haas, Lars M. Steinmetz
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Leukaemic stem cells drive acute myeloid leukaemia (AML) progression and relapse but they are incompletely characterized. Here, the authors combine single-cell transcriptomics and clonal tracking using nuclear and mitochondrial somatic variants to di
Externí odkaz:
https://doaj.org/article/7f3244539bc54da0bc5ec3fba0f6edbe
Autor:
Sergi Beneyto-Calabuig, Anne Kathrin Merbach, Jonas-Alexander Kniffka, Magdalena Antes, Chelsea Szu-Tu, Christian Rohde, Alexander Waclawiczek, Patrick Stelmach, Sarah Gräßle, Philip Pervan, Maike Janssen, Jonathan J.M. Landry, Vladimir Benes, Anna Jauch, Michaela Brough, Marcus Bauer, Birgit Besenbeck, Julia Felden, Sebastian Bäumer, Michael Hundemer, Tim Sauer, Caroline Pabst, Claudia Wickenhauser, Linus Angenendt, Christoph Schliemann, Andreas Trumpp, Simon Haas, Michael Scherer, Simon Raffel, Carsten Müller-Tidow, Lars Velten
Publikováno v:
Cell Stem Cell, 30 (5)
Inter-patient variability and the similarity of healthy and leukemic stem cells (LSCs) have impeded the characterization of LSCs in acute myeloid leukemia (AML) and their differentiation landscape. Here, we introduce CloneTracer, a novel method that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc5935e4747fc407077787ccc28ab68
http://hdl.handle.net/10230/57259
http://hdl.handle.net/10230/57259
Autor:
Sergi Beneyto-Calabuig, Anne Kathrin Ludwig, Jonas-Alexander Kniffka, Chelsea Szu-Tu, Christian Rohde, Magdalena Antes, Alexander Waclawiczek, Sarah Gräßle, Philip Pervan, Maike Janssen, Jonathan J. M. Landry, Vladimir Benes, Anna Jauch, Michaela Brough, Marcus Bauer, Birgit Besenbeck, Julia Felden, Sebastian Bäumer, Michael Hundemer, Tim Sauer, Caroline Pabst, Claudia Wickenhauser, Linus Angenendt, Christoph Schliemann, Andreas Trumpp, Simon Haas, Michael Scherer, Simon Raffel, Carsten Müller-Tidow, Lars Velten
Inter-patient variability and the similarity of healthy and leukemic stem cells have impeded the characterization of leukemic stem cells (LSCs) in acute myeloid leukemia (AML), and their differentiation landscape. Here, we introduce CloneTracer, a no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cedeb48ab7a036f46ac0d74ffd7b528
https://doi.org/10.1101/2022.08.29.505648
https://doi.org/10.1101/2022.08.29.505648
Autor:
Matteo Trovato, David Ochoa, Umut Yildiz, Kyung-Min Noh, Chelsea Szu Tu, Areeb Jawed, Athanasios Typas, Alexander G. Geiger, Vikram Govind Panse, Michaela Oborská-Oplová, Danish Memon, Mohammed Shahraz, Pedro Beltrao, Frank Stein, Lars M. Steinmetz, Cristina Viéitez, Marco Galardini, Mikhail M. Savitski, Bede P. Busby, André Mateus, Sibylle C. Vonesch, Clement M. Potel
Publikováno v:
Nature Biotechnology
Phosphorylation is a critical post-translational modification involved in the regulation of almost all cellular processes. However, fewer than 5% of thousands of recently discovered phosphosites have been functionally annotated. In this study, we dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cdd9e16de56dd6e8dde339025849852
Autor:
Chelsea Szu Tu, Bianca P. Hennig, Lars M, Sibylle C. Vonesch, Shengdi Li, Nikolay Dobrev, Steinmetz
Publikováno v:
G3: Genes|Genomes|Genetics
Through the increase in the capacity of sequencing machines massively parallel sequencing of thousands of samples in a single run is now possible. With the improved throughput and resulting drop in the price of sequencing, the cost and time for prepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::893c4000b54b9b3732b47dbf0f7c0e06
https://lirias.kuleuven.be/handle/123456789/675369
https://lirias.kuleuven.be/handle/123456789/675369
Autor:
Christoph Lutz, Simon Haas, Pablo Hernández-Malmierca, Lars Velten, Caroline Pabst, Daniel Nowak, Tobias Boch, Chelsea Szu-Tu, Benjamin A. Story, Aykut Demir, Robert Frömel, Wolf-Karsten Hofmann, Jennifer Milbank, Malte Paulsen, Daniel R. Leonce, Carsten Müller-Tidow, Simon Raffel, Andreas Trumpp, Lars M. Steinmetz, Johann-Christoph Jann
Publikováno v:
Nature Communications, 12 (1)
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Cancer stem cells drive disease progression and relapse in many types of cancer. Despite this, a thorough characterization of these cells remains elusive and with it the ability to eradicate cancer at its source. In acute myeloid leukemia (AML), leuk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ec4fb26a46903d0f84cbb2b6145fba
https://hdl.handle.net/20.500.11850/474268
https://hdl.handle.net/20.500.11850/474268
Autor:
Robert P. St.Onge, Wallace T Burnett, Alex R. Lederer, Maddison A Morgan, Wu Wei, Kevin Roy, Chelsea Szu Tu, Raeka S. Aiyar, Michelle Nguyen, James E. Haber, Marc L. Salit, Sibylle C. Vonesch, Justin D. Smith, Kevin M Orsley, Vytas A. Bankaitis, Julia Schulz, Sundari Suresh, Angela Chu, Gen Lin, Ronald W. Davis, Lars M. Steinmetz, Joe Horecka, Ashutosh Tripathi
Publikováno v:
Nature biotechnology
Our understanding of how genotype controls phenotype is limited by the scale at which we can precisely alter the genome and assess the phenotypic consequences of each perturbation. Here we describe a CRISPR-Cas9-based method for multiplexed accurate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7d365cf236adff204b8bd011b1059c9
https://doi.org/10.1038/nbt.4137
https://doi.org/10.1038/nbt.4137
Autor:
Lars Velten, Kim Remans, Lars M. Steinmetz, Hüseyin Besir, Bianca P. Hennig, Vladimir Rybin, Chelsea Szu Tu, Matthias Thoms, Ines Racke
Publikováno v:
G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 8, Iss 1, Pp 79-89 (2018)
G3: Genes, Genomes, Genetics, Vol 8, Iss 1, Pp 79-89 (2018)
Efficient preparation of high-quality sequencing libraries that well represent the biological sample is a key step for using next-generation sequencing in research. Tn5 enables fast, robust, and highly efficient processing of limited input material w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::330972c032351f509dcd85a44390d931
Autor:
Sibylle C. Vonesch, Chelsea Szu Tu, Bianca P. Hennig, Lars M. Steinmetz, Shengdi Li, Nikolay Dobrev
Publikováno v:
G3 Genes|Genomes|Genetics
bioRxiv
bioRxiv
Through the increase in the capacity of sequencing machines massively parallel sequencing of thousands of samples in a single run is now possible. With the improved throughput and resulting drop in the price of sequencing, the cost and time for prepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae32e5b072ed6700893bfb89d68ed1cf