Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Chelsea M. Smith"'
Autor:
Sarah R. Hengel, Katherine G. Oppenheimer, Chelsea M. Smith, Matthew A. Schaich, Hayley L. Rein, Julieta Martino, Kristie E. Darrah, Maggie Witham, Oluchi C. Ezekwenna, Kyle R. Burton, Bennett Van Houten, Maria Spies, Kara A. Bernstein
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Templated DNA repair that occurs during homologous recombination and replication stress relies on RAD51. RAD51 activity is positively regulated by BRCA2 and the RAD51 paralogs. The Shu complex is a RAD51 paralog-containing complex consisting
Externí odkaz:
https://doaj.org/article/323f61a200624d02a6355a27357eb8cb
Autor:
Chelsea M. Smith, Gaorav P. Gupta
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 11 (2023)
Deficiencies in homologous recombination (HR) repair lead to an accumulation of DNA damage and can predispose individuals to cancer. Polymerase theta (Pol θ, encoded by POLQ) is overexpressed by HR-deficient cancers and promotes cancer cell survival
Externí odkaz:
https://doaj.org/article/475662effcd54df99a7d238d5c3db799
Publikováno v:
Journal of Economic Entomology.
The Turkestan cockroach, Blatta lateralis (Walker), is a peridomestic pest of growing concern in the US Southwest. The parasitoid Aprostocetus hagenowii (Ratzburg) is used in IPM programs targeting other blattid cockroach species and may aid in B. la
Autor:
Ana M Chicas-Mosier, Rammohan R Balusu, Olufemi S Ajayi, Basu D Kafle, Tolulope Morawo, Gamze Mertoglu, Chelsea M Smith, Sanower Warsi, Henry Y Fadamiro
Publikováno v:
Environmental entomology.
The kudzu bug, Megacopta cribraria (Fabricius) (Hemiptera: Plataspidae), is a major economic pest of soybean in the southeastern United States. With climate warming, this pest is expected to move northward and cause additional crop damage. Parasitoid
Publikováno v:
Seminars in radiation oncology. 32(1)
Many cancer therapies, including radiotherapy, induce DSBs as the major driving mechanism for inducing cancer cell death. Thus, modulating DSB repair has immense potential for radiosensitization, although such interventions must be carefully designed
Autor:
Wanjuan Feng, Jang-Eun Cho, Nate Hathaway, Chelsea M. Smith, Juan Carvajal-Garcia, Dennis A. Simpson, Dale A. Ramsden, Kathryn M. Headley, Gaorav P. Gupta
Publikováno v:
Nucleic Acids Research
Genome integrity and genome engineering require efficient repair of DNA double-strand breaks (DSBs) by non-homologous end joining (NHEJ), homologous recombination (HR), or alternative end-joining pathways. Here we describe two complementary methods f
Publikováno v:
Southeastern Naturalist. 17:32-42
Knowledge of Alabama's Araneae fauna is limited, with estimates ranging from 580 to 1000 species within the state. Until now, the most recent surveys were conducted in the 1940s and focused on 3 families. Studies elsewhere indicate that spider divers
Autor:
Christopher J. Bakkenist, Jonathan Barroso-González, Julieta Martino, Moiseeva Tn, Gregory J. Brunette, Roderick J. O’Sullivan, Chelsea M Smith, Kara A. Bernstein
Publikováno v:
Nucleic Acids Research
RAD51 plays a central role in homologous recombination during double-strand break repair and in replication fork dynamics. Misregulation of RAD51 is associated with genetic instability and cancer. RAD51 is regulated by many accessory proteins includi
Publikováno v:
Aquatic toxicology (Amsterdam, Netherlands). 210
Roundup and other glyphosate-based herbicides are the most commonly used herbicides in the world, yet their effects on developing fish embryos are not clearly understood. The present study, therefore, examined developmental teratogenic effects and ad
Autor:
Robert C. Fleischer, Seth D. Newsome, Chelsea M. Smith, Jon M. Erlandson, Wendy Teeter, René L. Vellanoweth, Paul W. Collins, T. Scott Sillett, Torben C. Rick, Courtney A. Hofman, Jesús E. Maldonado, Katherine Ralls
Publikováno v:
Quaternary Science Reviews. 146:147-160
Understanding how human activities have influenced the foraging ecology of wildlife is important as our planet faces ongoing and impending habitat and climatic change. We review the canine surrogacy approach (CSA)—a tool for comparing human, dog, a