Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Chelsea M. Burgwin"'
Autor:
Robert Lafyatis, Stephen H. Clark, Chelsea M. Burgwin, Minghua Wu, Carol M. Artlett, Adam Harris, Elizabeth P. Blankenhorn, Matthew B. Greenblatt, Kristen B. Long, John Varga, Jun Wei, Zhenghui Li, Michael L. Whitfield, Jennifer L. Sargent, Antonios O. Aliprantis, Jaclyn N. Taroni, Raphael Lemaire
Publikováno v:
Arthritis & Rheumatology. 68:2003-2015
Objective Understanding the pathogenesis of systemic sclerosis (SSc) is confounded by considerable disease heterogeneity. Animal models of SSc that recapitulate distinct subsets of disease at the molecular level have not been delineated. We applied i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d57ab25f07200f424d9ed78008463b29
https://doi.org/10.1002/art.39658
https://doi.org/10.1002/art.39658
Autor:
Nuzhat Motlekar, Chelsea M. Burgwin, Andrew D. Napper, Fei Huang, Scott L. Diamond, Alexander V. Mazin
Publikováno v:
ACS Chemical Biology. 6:628-635
RAD51 is a key protein of homologous recombination that plays a critical role in the repair of DNA double-strand breaks (DSB) and interstrand cross links (ICL). To better understand the cellular function(s) of human RAD51, we propose to develop speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bf6b889c7302b213c6d0b06764bbb4c
https://doi.org/10.1021/cb100428c
https://doi.org/10.1021/cb100428c
Autor:
Chelsea M. Burgwin, Elizabeth P. Blankenhorn, Kristen B. Long, Richard B. Huneke, Carol M. Artlett
Rationale: The Tight Skin 2 (Tsk2) mouse model of systemic sclerosis (SSc) has many features of human disease, including tight skin, excessive collagen deposition, alterations in the extracellular matrix (ECM), increased elastic fibers, and occurrenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f4c569dcecf2248ba89f4eaf90c6514
https://europepmc.org/articles/PMC4152796/
https://europepmc.org/articles/PMC4152796/
Autor:
Garth D. Ehrlich, Susanna G. Choe, Rory A. Eutsey, Kristen B. Long, Elizabeth P. Blankenhorn, Chelsea M. Burgwin, Josh Earl, Viktor Martyanov, Carol M. Artlett, Zhenghui Li, Azad Ahmed, Sihem Sassi-Gaha, Michael L. Whitfield
Publikováno v:
The Journal of investigative dermatology
Systemic sclerosis (SSc) is a polygenic, autoimmune disorder of unknown etiology, characterized by the excessive accumulation of extracellular matrix (ECM) proteins, vascular alterations, and autoantibodies. The tight skin (Tsk)2/+ mouse model of SSc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::337be6655220020cf882acca4e08c77d