Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Chelsea Jenkins"'
Autor:
Kristen Jones, Clare Keddy, Chelsea Jenkins, Katelyn Nicholson, Ujwal Shinde, Monika A. Davare
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The ROS1 receptor tyrosine kinase (RTK) possesses the largest extracellular amino-terminal domain (ECD) among the human RTK family, yet the mechanisms regulating its activation are not fully understood. While chimeric ROS1 fusion proteins, r
Externí odkaz:
https://doaj.org/article/66839e6de01149af9218b507876cdf74
Publikováno v:
Anemia, Vol 2012 (2012)
The Fanconi Anemia (FA) pathway consists of proteins involved in repairing DNA damage, including interstrand cross-links (ICLs). The pathway contains an upstream multiprotein core complex that mediates the monoubiquitylation of the FANCD2 and FANCI h
Externí odkaz:
https://doaj.org/article/04fa66391eed43e3be01ed4885f7c520
Autor:
Joshi J. Alumkal, Zheng Xia, Joel A. Yates, Eric Campeau, Sanjay Lakhotia, Sarah Attwell, Emily M. Gesner, Arvind Rao, Armand Bankhead, Daniel E. Spratt, Eric J. Small, Felix Y. Feng, Wassim Abida, Rahul Aggarwal, Jonathan Z. Sexton, Samuel K. Handelman, Eva Corey, Peter S. Nelson, Ilsa M. Coleman, Jared M. Lucas, Colm Morrissey, Mark P. Labrecque, Himisha Beltran, Chao Zhang, Jacob A. Schwartzman, Joshua A. Urrutia, Eva S. Rodansky, Anbarasu Kumaraswamy, Xiangnan Guan, David Sampson, Daniel J. Coleman, Chelsea Jenkins, Katherine Welker Leng, William K. Storck, Duanchen Sun, Dae-Hwan Kim
Supplementary Table S5 from BET Bromodomain Inhibition Blocks an AR-Repressed, E2F1-Activated Treatment-Emergent Neuroendocrine Prostate Cancer Lineage Plasticity Program
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184f8ddc3a8bdce5db61ce2644baf9fd
https://doi.org/10.1158/1078-0432.22481639
https://doi.org/10.1158/1078-0432.22481639
Autor:
Joshi J. Alumkal, Zheng Xia, Joel A. Yates, Eric Campeau, Sanjay Lakhotia, Sarah Attwell, Emily M. Gesner, Arvind Rao, Armand Bankhead, Daniel E. Spratt, Eric J. Small, Felix Y. Feng, Wassim Abida, Rahul Aggarwal, Jonathan Z. Sexton, Samuel K. Handelman, Eva Corey, Peter S. Nelson, Ilsa M. Coleman, Jared M. Lucas, Colm Morrissey, Mark P. Labrecque, Himisha Beltran, Chao Zhang, Jacob A. Schwartzman, Joshua A. Urrutia, Eva S. Rodansky, Anbarasu Kumaraswamy, Xiangnan Guan, David Sampson, Daniel J. Coleman, Chelsea Jenkins, Katherine Welker Leng, William K. Storck, Duanchen Sun, Dae-Hwan Kim
Supplementary Figure S3 from BET Bromodomain Inhibition Blocks an AR-Repressed, E2F1-Activated Treatment-Emergent Neuroendocrine Prostate Cancer Lineage Plasticity Program
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::380d5df6f1565ca06f349c5d1c89338e
https://doi.org/10.1158/1078-0432.22481663.v1
https://doi.org/10.1158/1078-0432.22481663.v1
Autor:
Joshi J. Alumkal, Zheng Xia, Joel A. Yates, Eric Campeau, Sanjay Lakhotia, Sarah Attwell, Emily M. Gesner, Arvind Rao, Armand Bankhead, Daniel E. Spratt, Eric J. Small, Felix Y. Feng, Wassim Abida, Rahul Aggarwal, Jonathan Z. Sexton, Samuel K. Handelman, Eva Corey, Peter S. Nelson, Ilsa M. Coleman, Jared M. Lucas, Colm Morrissey, Mark P. Labrecque, Himisha Beltran, Chao Zhang, Jacob A. Schwartzman, Joshua A. Urrutia, Eva S. Rodansky, Anbarasu Kumaraswamy, Xiangnan Guan, David Sampson, Daniel J. Coleman, Chelsea Jenkins, Katherine Welker Leng, William K. Storck, Duanchen Sun, Dae-Hwan Kim
Supplementary Data from BET Bromodomain Inhibition Blocks an AR-Repressed, E2F1-Activated Treatment-Emergent Neuroendocrine Prostate Cancer Lineage Plasticity Program
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::212ea32b543bc433b2e2d94d66815153
https://doi.org/10.1158/1078-0432.22481681
https://doi.org/10.1158/1078-0432.22481681
Autor:
Joshi J. Alumkal, Zheng Xia, Joel A. Yates, Eric Campeau, Sanjay Lakhotia, Sarah Attwell, Emily M. Gesner, Arvind Rao, Armand Bankhead, Daniel E. Spratt, Eric J. Small, Felix Y. Feng, Wassim Abida, Rahul Aggarwal, Jonathan Z. Sexton, Samuel K. Handelman, Eva Corey, Peter S. Nelson, Ilsa M. Coleman, Jared M. Lucas, Colm Morrissey, Mark P. Labrecque, Himisha Beltran, Chao Zhang, Jacob A. Schwartzman, Joshua A. Urrutia, Eva S. Rodansky, Anbarasu Kumaraswamy, Xiangnan Guan, David Sampson, Daniel J. Coleman, Chelsea Jenkins, Katherine Welker Leng, William K. Storck, Duanchen Sun, Dae-Hwan Kim
Supplementary Table S2 S4 S6 S7 from BET Bromodomain Inhibition Blocks an AR-Repressed, E2F1-Activated Treatment-Emergent Neuroendocrine Prostate Cancer Lineage Plasticity Program
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16078ca74f4249c0affafe9aadcfadc3
https://doi.org/10.1158/1078-0432.22481645.v1
https://doi.org/10.1158/1078-0432.22481645.v1
Autor:
Joshi J. Alumkal, Zheng Xia, Joel A. Yates, Eric Campeau, Sanjay Lakhotia, Sarah Attwell, Emily M. Gesner, Arvind Rao, Armand Bankhead, Daniel E. Spratt, Eric J. Small, Felix Y. Feng, Wassim Abida, Rahul Aggarwal, Jonathan Z. Sexton, Samuel K. Handelman, Eva Corey, Peter S. Nelson, Ilsa M. Coleman, Jared M. Lucas, Colm Morrissey, Mark P. Labrecque, Himisha Beltran, Chao Zhang, Jacob A. Schwartzman, Joshua A. Urrutia, Eva S. Rodansky, Anbarasu Kumaraswamy, Xiangnan Guan, David Sampson, Daniel J. Coleman, Chelsea Jenkins, Katherine Welker Leng, William K. Storck, Duanchen Sun, Dae-Hwan Kim
Purpose:Lineage plasticity in prostate cancer—most commonly exemplified by loss of androgen receptor (AR) signaling and a switch from a luminal to alternate differentiation program—is now recognized as a treatment resistance mechanism. Lineage pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::048c54987968c92a1c3c681235482238
https://doi.org/10.1158/1078-0432.c.6530747.v1
https://doi.org/10.1158/1078-0432.c.6530747.v1
Autor:
Joshi J. Alumkal, Zheng Xia, Joel A. Yates, Eric Campeau, Sanjay Lakhotia, Sarah Attwell, Emily M. Gesner, Arvind Rao, Armand Bankhead, Daniel E. Spratt, Eric J. Small, Felix Y. Feng, Wassim Abida, Rahul Aggarwal, Jonathan Z. Sexton, Samuel K. Handelman, Eva Corey, Peter S. Nelson, Ilsa M. Coleman, Jared M. Lucas, Colm Morrissey, Mark P. Labrecque, Himisha Beltran, Chao Zhang, Jacob A. Schwartzman, Joshua A. Urrutia, Eva S. Rodansky, Anbarasu Kumaraswamy, Xiangnan Guan, David Sampson, Daniel J. Coleman, Chelsea Jenkins, Katherine Welker Leng, William K. Storck, Duanchen Sun, Dae-Hwan Kim
Supplementary Table S8-S12 from BET Bromodomain Inhibition Blocks an AR-Repressed, E2F1-Activated Treatment-Emergent Neuroendocrine Prostate Cancer Lineage Plasticity Program
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a3a1a10765a705a50b969da1a429c43
https://doi.org/10.1158/1078-0432.22481636.v1
https://doi.org/10.1158/1078-0432.22481636.v1
Autor:
Camille Collier, Matthew McWhorter, Kelly Wucherer, Chelsea Jenkins, Alexandra Bartlett, Robert Eil
Publikováno v:
Cancer Research. 83:613-613
Background: The past 20 years of translational oncology provide a framework in which the ability to eradicate cancer has increased in direct relation to our understanding of T cell biology. The cancer-killing functions of T cells are often compromise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f006d511de5e039cc9ae7d438c5cdb4
https://doi.org/10.1158/1538-7445.am2023-613
https://doi.org/10.1158/1538-7445.am2023-613
Autor:
Adam J. Schoenfeld, Clare Keddy, Alexander Drilon, Sudarshan Iyer, Monika A. Davare, Chelsea Jenkins
Publikováno v:
Nat Rev Clin Oncol
The proto-oncogene ROS1 encodes a receptor tyrosine kinase with an unknown physiological role in humans. Somatic chromosomal fusions involving ROS1 produce chimeric oncoproteins that drive a diverse range of cancers in adult and paediatric patients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df6f02df9846f14fc3b8dfd06c6cf4dc
https://doi.org/10.1038/s41571-020-0408-9
https://doi.org/10.1038/s41571-020-0408-9