Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Chelsea DeLeon"'
Autor:
Stefan Gahbauer, Chelsea DeLeon, Joao M. Braz, Veronica Craik, Hye Jin Kang, Xiaobo Wan, Xi-Ping Huang, Christian B. Billesbølle, Yongfeng Liu, Tao Che, Ishan Deshpande, Madison Jewell, Elissa A. Fink, Ivan S. Kondratov, Yurii S. Moroz, John J. Irwin, Allan I. Basbaum, Bryan L. Roth, Brian K. Shoichet
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract The lipid prostaglandin E2 (PGE2) mediates inflammatory pain by activating G protein-coupled receptors, including the prostaglandin E2 receptor 4 (EP4R). Nonsteroidal anti-inflammatory drugs (NSAIDs) reduce nociception by inhibiting prostagl
Externí odkaz:
https://doaj.org/article/5afef5b1703241589164379113e645d4
Autor:
Chelsea DeLeon, Helen H. Wang, Joseph Gunn, McKenna Wilhelm, Aidan Cole, Stacy Arnett, David Q-H. Wang, Christopher K. Arnatt
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 5, Pp 767-777 (2020)
Many clinical studies and epidemiological investigations have clearly demonstrated that women are twice as likely to develop cholesterol gallstones as men, and oral contraceptives and other estrogen therapies dramatically increase that risk. Further,
Externí odkaz:
https://doaj.org/article/5630faffec284745a5663911943e8dce
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
There are gender differences between men and women in many physiological functions and diseases, which indicates that female sex hormones may be important. Traditionally, estrogen exerts its biological activities by activating two classical nuclear e
Externí odkaz:
https://doaj.org/article/bd6ce570efaf440686a6c8508172cc27
Autor:
Chelsea DeLeon, Kyle Pemberton, Michael Green, Vanja Kalajdzic, Martina Rosato, Fenglian Xu, Christopher Arnatt
Publikováno v:
ACS chemical neuroscience. 13(8)
Numerous studies have reported neuroprotective and procognitive effects of estrogens. The estrogen 17β-estradiol (E2) activates both the classical nuclear estrogen receptors ERα and ERβ as well as the G protein-coupled estrogen receptor (GPER). Th
Publikováno v:
Journal of Chemical Education. 97:4453-4461
This work explores the interface between 3D-printing, material sciences, and microfluidics with electrochemical detection in an undergraduate laboratory. This work includes a module for the characterization and electrochemical analysis of microelectr
Autor:
Aidan Cole, McKenna Wilhelm, Chelsea DeLeon, Stacy D. Arnett, David Q.-H. Wang, Helen H. Wang, Christopher K. Arnatt, Joseph Gunn
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 5, Pp 767-777 (2020)
J Lipid Res
J Lipid Res
Many clinical studies and epidemiological investigations have clearly demonstrated that women are twice as likely to develop cholesterol gallstones as men, and oral contraceptives and other estrogen therapies dramatically increase that risk. Further,
Publikováno v:
eneuro. 9:ENEURO.0475-21.2022
Estrogen plays fundamental roles in nervous system development and function. Traditional studies examining the effect of estrogen in the brain have focused on the nuclear estrogen receptors (ERs), ERα and ERβ. Studies related to the extranuclear, m
Publikováno v:
Frontiers in Endocrinology
Frontiers in Endocrinology, Vol 11 (2020)
Frontiers in Endocrinology, Vol 11 (2020)
There are gender differences between men and women in many physiological functions and diseases, which indicates that female sex hormones may be important. Traditionally, estrogen exerts its biological activities by activating two classical nuclear e
Autor:
Kathryn Braden, Chelsea DeLeon, John K. Walker, Nick Latzo, Daniela Salvemini, Luigino Antonio Giancotti, Bonne M. Thompson, Timothy M. Doyle, Napoleon D’Cunha, Jeffrey G. McDonald, Christopher K. Arnatt, Zhoumou Chen, Grant R. Kolar, Terri L. Boehm
Publikováno v:
J Pharmacol Exp Ther
Neuropathic pain is a debilitating public health concern for which novel non-narcotic therapeutic targets are desperately needed. Using unbiased transcriptomic screening of the dorsal horn spinal cord after nerve injury we have identified that Gpr183
Autor:
Daniela Salvemini, Zhoumou Chen, Grant R. Kolar, Kathryn Braden, Terri L. Boehm, Livio Luongo, Timothy M. Doyle, John K. Walker, Chelsea DeLeon, Luigi Giancotti, Nicholas George Latzo, Napoleon D’Cunha, Christopher K. Arnatt
Publikováno v:
The FASEB Journal. 34:1-1