CSAP localizes to polyglutamylated microtubules and promotes proper cilia function and zebrafish development

Autor: Chelsea B. Backer, Chad G. Pearson, Iain M. Cheeseman, Jennifer H. Gutzman

Publikováno v: Molecular Biology of the Cell
American Society of Cell Biology

The diverse populations of microtubule polymers in cells are functionally distinguished by different posttranslational modifications, including polyglutamylation. Polyglutamylation is enriched on subsets of microtubules including those found in the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f613032b101573bd4a6edd629178d174
http://europepmc.org/articles/PMC3364176

The Human Kinetochore Ska1 Complex Facilitates Microtubule Depolymerization-Coupled Motility

Autor: Chelsea B. Backer, Julie P.I. Welburn, John R. Yates, Iain M. Cheeseman, Elizabeth M. Wilson-Kubalek, Ekaterina L. Grishchuk

Publikováno v: Welburn, J P I, Grishchuk, E L, Backer, C B, Wilson-Kubalek, E M, Yates, J R & Cheeseman, I M 2009, ' The Human Kinetochore Ska1 Complex Facilitates Microtubule Depolymerization-Coupled Motility ', Developmental Cell, vol. 16, no. 3, pp. 374-385 . https://doi.org/10.1016/j.devcel.2009.01.011

SummaryMitotic chromosome segregation requires that kinetochores attach to microtubule polymers and harness microtubule dynamics to drive chromosome movement. In budding yeast, the Dam1 complex couples kinetochores with microtubule depolymerization.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::097ddfc5a2db19cf37b38bc7a30f7cda

Genetic association of cutaneous neonatal lupus with HLA class II and tumor necrosis factor ?: Implications for pathogenesis

Autor: Steven R. Cohen, Lela A. Lee, Chelsea B. Backer, Mary Wu Chang, Jill P. Buyon, Robert R. Clancy, Xiaoming Yin

Publikováno v: Arthritis & Rheumatism. 50:2598-2603

Objective Cutaneous neonatal lupus resembles subacute cutaneous lupus erythematosus (SCLE), and photosensitivity is a common symptom. Tumor necrosis factor α (TNFα) release by ultraviolet light–exposed keratinocytes may be exaggerated in SCLE pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc445e4db3150faa4f87cc4a4c18c2a5
https://doi.org/10.1002/art.20442

The CENP-S complex is essential for the stable assembly of outer kinetochore structure

Autor: Miho Amano, Iain M. Cheeseman, Aussie Suzuki, Tetsuya Hori, Katsuya Okawa, Tatsuo Fukagawa, Chelsea B. Backer

Publikováno v: The Journal of Cell Biology
Publisher

The constitutive centromere-associated network (CCAN) proteins are central to kinetochore assembly. To define the molecular architecture of this critical kinetochore network, we sought to determine the full complement of CCAN components and to define

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0c235b4ad6ee371e2bd47b293f17e03
https://pubmed.ncbi.nlm.nih.gov/19620631

Genetic association of cutaneous neonatal lupus with HLA class II and tumor necrosis factor α: Implications for pathogenesis.

Autor: Robert M. Clancy, Chelsea B. Backer, Xiaoming Yin, Mary Wu Chang, Steven R. Cohen, Lela A. Lee, Jill P. Buyon

Publikováno v: Arthritis & Rheumatism; Aug2004, Vol. 50 Issue 8, p2598-2603, 6p