Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Chelsea A, O'Driscoll"'
Autor:
Chelsea A. O’Driscoll, Leah A. Owens, Madeline E. Gallo, Erica J. Hoffmann, Amin Afrazi, Mei Han, John H. Fechner, James J. Schauer, Christopher A. Bradfield, Joshua D. Mezrich
Publikováno v:
Particle and Fibre Toxicology, Vol 15, Iss 1, Pp 1-19 (2018)
Abstract Background Exposure to particulate matter (PM) has been associated with increased incidence and severity of autoimmune disease. Diesel PM is primarily composed of an elemental carbon core and adsorbed organic compounds such as polycyclic aro
Externí odkaz:
https://doaj.org/article/d30777f5567343598dfa7505dd01e0d9
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
This review examines the current literature on the effects of atmospheric particulate matter (PM) on autoimmune disease and proposes a new role for the aryl hydrocarbon receptor (AHR) as a modulator of T cells in PM-mediated autoimmune disease. There
Externí odkaz:
https://doaj.org/article/7413df12d38048f1a45d6bc9b1008553
Autor:
Chelsea A O'Driscoll, Madeline E Gallo, Erica J Hoffmann, John H Fechner, James J Schauer, Christopher A Bradfield, Joshua D Mezrich
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209690 (2018)
Atmospheric particulate matter (PM) is a complex component of air pollution that is a composed of inorganic and organic constituents. The chemically-extracted organic fraction (OF) of PM excludes inorganics but retains most organic constituents like
Externí odkaz:
https://doaj.org/article/fa02168adecf4da3ad74f712d7de9666
Autor:
Lisa L. Abler, Sara A. Colopy, Zun-Yi Wang, Chad M. Vezina, Kimberly P. Keil Stietz, Mieke Baan, Dale E. Bjorling, Dawn Belt Davis, Peiqing Wang, Steven R Oakes, Faye A. Hartmann, Chelsea A. O’Driscoll, Jonathan N. Ouellette, Jyoti J. Watters, Matthew D Grimes, Michelle E. Kimple, Shannon J. Gallagher, Stephanie M Crader-Smith, Vatsal Mehta, Gordon S. Mitchell
Publikováno v:
Am J Physiol Renal Physiol
We used male BTBR mice carrying the Lep(ob) mutation, which are subject to severe and progressive obesity and diabetes beginning at 6 wk of age, to examine the influence of one specific manifestation of sleep apnea, intermittent hypoxia (IH), on male
Autor:
Chelsea A. O’Driscoll, Hannah Ruetten, Britta Chelgren, Chad M. Vezina, Mark Cadena, Lisa L. Abler, Jonathan Zhu, Dale E. Bjorling, Kyle A Wegner, Zunyi Wang, Jaskiran K Sandhu, Peiqing Wang, Helen L Zhang, Simran K. Sandhu, Jonathan Barasch, Tian Shen, Brett Mueller
Publikováno v:
American Journal of Physiology-Renal Physiology. 320:F31-F46
Bacterial infection is one known etiology of prostatic inflammation. Prostatic inflammation is associated with prostatic collagen accumulation and both are linked to progressive lower urinary tract symptoms in men. We characterized a model of prostat
Autor:
Kyle A, Wegner, Hannah, Ruetten, Nicholas M, Girardi, Chelsea A, O'Driscoll, Jaskiran K, Sandhu, Anne E, Turco, Lisa L, Abler, Peiqing, Wang, Zunyi, Wang, Dale E, Bjorling, Rita, Malinowski, Richard E, Peterson, Douglas W, Strand, Paul C, Marker, Chad M, Vezina
Publikováno v:
Am J Clin Exp Urol
Urinary voiding dysfunction in aging men can cause bothersome symptoms and irreparable tissue damage. Underlying mechanisms are not fully known. We previously demonstrated that subcutaneous, slow-release testosterone and estradiol implants (T+E2) dri
Autor:
Leah A. Owens, Christopher A. Bradfield, Chelsea A. O’Driscoll, James J. Schauer, Amin Afrazi, John H. Fechner, Mei Han, Joshua D. Mezrich, Erica J. Hoffmann, Madeline E. Gallo
Publikováno v:
Environmental Research. 168:178-192
Background Autoimmune diseases have increased in incidence and prevalence worldwide. While genetic predispositions play a role, environmental factors are a major contributor. Atmospheric particulate matter (PM) is a complex mixture composed of metals
Autor:
Leah A. Owens, James J. Schauer, Joshua D. Mezrich, John H. Fechner, Mei Han, Christopher A. Bradfield, Erica J. Hoffmann, Madeline E. Gallo, Chelsea A. O’Driscoll, Amin Afrazi
Publikováno v:
Particle and Fibre Toxicology, Vol 15, Iss 1, Pp 1-19 (2018)
Particle and Fibre Toxicology
Particle and Fibre Toxicology
Background Exposure to particulate matter (PM) has been associated with increased incidence and severity of autoimmune disease. Diesel PM is primarily composed of an elemental carbon core and adsorbed organic compounds such as polycyclic aromatic hyd
Autor:
Joshua D. Mezrich, John H. Fechner, Madeline E. Gallo, James J. Schauer, Chelsea A. O’Driscoll
Atmospheric particulate matter (PM) is a complex component of air pollution and the leading environmental risk factor for death worldwide. PM is formed from a combination of primary sources that emit PM directly into the atmosphere and secondary sour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e22e9b445fcff027020dbf6451cc0d1
https://europepmc.org/articles/PMC7065493/
https://europepmc.org/articles/PMC7065493/
Autor:
John H. Fechner, Amanda Mueller, Leah A. Owens, Jeremy A. Sullivan, Joshua D. Mezrich, Ling Zhou, Walker Julliard, Lynn Frydrych, Chelsea A. O’Driscoll
Publikováno v:
Transplantation Direct
Background Exposure to pollutants through inhalation is a risk factor for lung diseases including cancer, asthma, and lung transplant rejection, but knowledge of the effects of inhaled pollutants on pathologies outside of the lung is limited. Methods