Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Chella David"'
Autor:
Ashutosh Mangalam, Shailesh K. Shahi, David Luckey, Melissa Karau, Eric Marietta, Ningling Luo, Rok Seon Choung, Josephine Ju, Ramakrishna Sompallae, Katherine Gibson-Corley, Robin Patel, Moses Rodriguez, Chella David, Veena Taneja, Joseph Murray
Publikováno v:
Cell Reports, Vol 20, Iss 6, Pp 1269-1277 (2017)
The human gut is colonized by a large number of microorganisms (∼1013 bacteria) that support various physiologic functions. A perturbation in the healthy gut microbiome might lead to the development of inflammatory diseases, such as multiple sclero
Externí odkaz:
https://doaj.org/article/b4fd6935ed0142c1ade44334911463e6
Autor:
Jane M Natividad, Xianxi Huang, Emma Slack, Jennifer Jury, Yolanda Sanz, Chella David, Emmanuel Denou, Pinchang Yang, Joseph Murray, Kathy D McCoy, Elena F Verdú
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6472 (2009)
BACKGROUND AND AIMS:Excessive uptake of commensal bacterial antigens through a permeable intestinal barrier may influence host responses to specific antigen in a genetically predisposed host. The aim of this study was to investigate whether intestina
Externí odkaz:
https://doaj.org/article/469f604bab94428c9c077388efe372f5
Autor:
Eric Marietta, Kay Black, Michael Camilleri, Patricia Krause, Roy S. Rogers, Chella David, Mark R. Pittelkow, Joseph A. Murray
Publikováno v:
Journal of Clinical Investigation. 114:1090-1097
Dermatitis herpetiformis (DH) is an autoimmune blistering skin disorder that is associated with gluten sensitivity. It presents as a papulovesicular rash and is often associated with enteropathy. The rash resolves when the patient is placed on a glut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1a0c9d172c87344923ade0eb4e463b7
https://doi.org/10.1172/jci200421055
https://doi.org/10.1172/jci200421055
Autor:
Rossana, D'Arienzo, Rosita, Stefanile, Francesco, Maurano, Diomira, Luongo, Paolo, Bergamo, Giuseppe, Mazzarella, Riccardo, Troncone, Salvatore, Auricchio, Chella, David, Mauro, Rossi
Publikováno v:
European journal of immunology. 39(12)
Celiac disease (CD) is an enteropathy triggered by gluten and mediated by CD4+ T cells. A complete understanding of CD immunopathogenesis has been hindered due to the lack of adequate in vivo models. Here, we explored the effect of the inhibition of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d1f7df19a28c95898d008aa12d67bc5a
https://pubmed.ncbi.nlm.nih.gov/19795413
https://pubmed.ncbi.nlm.nih.gov/19795413
Autor:
Ashutosh Mangalam, David Luckey, Michele Smart, Vivekananda Sarangi, Shailendra Giri, Moses Rodriguez, Chella David
Publikováno v:
The Journal of Immunology. 194:116.2-116.2
MS is an autoimmune disease of the CNS and among all the genetic factors; MHC class-II molecules show the strongest association. To better understand the role of MHC class-II (HLA-DR/DQ) genes in susceptibility and resistance to MS, we utilized trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7659659c2de696677751fedcef8b52a
https://doi.org/10.4049/jimmunol.194.supp.116.2
https://doi.org/10.4049/jimmunol.194.supp.116.2
Autor:
Ashutosh Mangalam, Ningling Luo, David Luckey, Louisa Papke, Michele Smart, Shailendra Giri, Moses Rodriguez, Chella David
Publikováno v:
The Journal of Immunology. 192:178.3-178.3
Among all the genetic factors linked with multiple sclerosis (MS), MHC class-II molecules show the strongest association. Generation of HLA class-II transgenic mice has helped to elucidate the role of HLA class-II gene in MS. We have shown that the h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85ac8a86cc944d2752c0ec036cc97e1d
https://doi.org/10.4049/jimmunol.192.supp.178.3
https://doi.org/10.4049/jimmunol.192.supp.178.3
Publikováno v:
The Journal of Immunology. 178:S236-S237
DRB1*0401 has been associated with predisposition to rheumatoid arthritis while DRB1*0402 is associated with resistance. We have generated transgenic mice lacking endogenous H2-A and E molecules (AEo) but expressing DRB1*0401 or DRB1*0402 molecules.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07c2ef81684721ccdcbefeae3f1b6478
https://doi.org/10.4049/jimmunol.178.supp.130.45
https://doi.org/10.4049/jimmunol.178.supp.130.45
Publikováno v:
The Journal of Immunology. 190:175.8-175.8
HLA-DRB1*0401 has been associated with predisposition to develop rheumatoid arthritis (RA) while *0402 has been linked with resistance to develop RA. Using transgenic mice, we showed that *0401 mice are susceptible to develop collagen-induced arthrit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16b28cd8cac511536d5e2fa43415cadb
https://doi.org/10.4049/jimmunol.190.supp.175.8
https://doi.org/10.4049/jimmunol.190.supp.175.8
Publikováno v:
The Journal of Immunology. 184:93.27-93.27
HLA-DQB1*0302/DQA1*0301 renders humans and transgenic mice susceptible to develop arthritis while HLA-DQB1*0601/DQA1*0103 has been associated with resistance to arthritis in both. However, some patients of rheumatoid arthritis carry the non-associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::073377843e47389ac25ffcf107b0e0d0
https://doi.org/10.4049/jimmunol.184.supp.93.27
https://doi.org/10.4049/jimmunol.184.supp.93.27
Autor:
Mary Mattapallil, Phyllis Silver, Joseph Mattapallil, Reiko Horai, Zaruhi Karabekian, Hugh McDowell, Chi-Chao Chan, Eddie James, William Kwok, Chella David, Rachel Caspi
Publikováno v:
The Journal of Immunology. 184:93.1-93.1
Autoimmune uveitis affects 150,000 Americans annually and is a leading cause of blindness. Pathogenesis is thought to involve T cell mediated responses to retinal proteins, such as retinal arrestin (S-Ag). Susceptibility to autoimmune uveitis is stro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec70b7b2a99ebf29afd9e262e7b4bca9
https://doi.org/10.4049/jimmunol.184.supp.93.1
https://doi.org/10.4049/jimmunol.184.supp.93.1