Innovative antitumoral platinum (II) compounds as chemotherapeutic and immunotherapeutic agents

Autor: Wantz, M., Chekkat, N., Bouché, M., Dahm, G., Bellemin-Laponnaz, S., Fournel, S., Wantz1, M, Chekkat1, N, Bouche´, M, Dahm2, G, Kichler, A., Frisch, B., Bellemin-Laponnaz2, S, Fournel1, S

Publikováno v: European Journal of Cancer
6tth International Cancer Immunotherapy Conference in Europe (ITOC) Apr 11-13, 2019 Vienna, AUSTRIA Cancer Drug Dev Forum; Soc Immunotherapy Cancer
6tth International Cancer Immunotherapy Conference in Europe (ITOC) Apr 11-13, 2019 Vienna, AUSTRIA Cancer Drug Dev Forum; Soc Immunotherapy Cancer, 2019, Vienna, Austria. pp.S31-S32, ⟨10.1016/j.ejca.2019.01.094⟩

International audience; Background: Platinum (II)-based drugs are widely used chemother-apeutic agents. However, as they have many side effects, numerous platinum (Pt) derivatives have been developed during the last years. Furthermore, some cancer tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b6f713bec396c53fb6e7898f54add3
https://hal.archives-ouvertes.fr/hal-02347590/document

Cysteine-rich domain one of CD40 mediates receptor self-assembly

Autor: Smulski, C. (Cristian) R. (R), Beyrath, J. (Julien), Decossas, M. (Marion), Chekkat, N. (Neïla), Wolff, P. (Philippe), Estieu-Gionnet, K. (Karine), Guichard, G. (Gilles), Speiser, D. (Daniel), Schneider, P. (Pascal), Fournel, S. (Sylvie)

The activation of CD40 on B cells, macrophages and dendritic cells by its ligand CD154 (CD40L) is essential for the development of humoral and cellular immune responses. CD40L and other TNF superfamily ligands are non-covalent homotrimers, but the fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4060::dcc45337c4961f608c0c9c867d34953a

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