Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Chein-Fuang Huang"'
Autor:
Hsiao-Wen Kao, Masashi Sanada, Der-Cherng Liang, Chang-Liang Lai, En-Hui Lee, Ming-Chung Kuo, Tung-Liang Lin, Yu-Shu Shih, Jin-Hou Wu, Chein-Fuang Huang, Seishi Ogawa, Lee-Yung Shih
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 11, Pp 1035-1042 (2011)
The molecular pathogenesis of myelodysplastic syndrome (MDS) and its progression to secondary acute myeloid leukemia (sAML) remain to be explored. Somatic C-CBL mutations were recently described in MDS. Our study aimed to determine the role of C-CBL
Externí odkaz:
https://doaj.org/article/942611ed06c648c58ce9c205bbd2f627
Autor:
Tung-Liang Lin, Yasunobu Nagata, Hsiao-Wen Kao, Masashi Sanada, Yusuke Okuno, Chein-Fuang Huang, Der-Cherng Liang, Ming-Chung Kuo, Chang-Liang Lai, En-Hui Lee, Yu-Shu Shih, Hiroko Tanaka, Yuichi Shiraishi, Kenichi Chiba, Tung-Huei Lin, Jin-Hou Wu, Satoru Miyano, Seishi Ogawa, Lee-Yung Shih
Publikováno v:
Haematologica, Vol 99, Iss 1 (2014)
Somatic mutations of TET2, IDH1, and IDH2 have been described in myelodysplastic syndrome. The impact of these mutations on outcome of myelodysplastic syndrome and their progression to secondary acute myeloid leukemia remains unclear. Mutation status
Externí odkaz:
https://doaj.org/article/d53cabcadf364b7ab452678d42049b06
Autor:
Chein-Fuang Huang, 黃千芳
88
The identity and the specific location of the point mutations in the guanidine nucleotide-binding region of Ras protein N-termini affected the Ras GTP-locked ability, GTPase activity, and moreover the efficiency of cellular transformation. In
The identity and the specific location of the point mutations in the guanidine nucleotide-binding region of Ras protein N-termini affected the Ras GTP-locked ability, GTPase activity, and moreover the efficiency of cellular transformation. In
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/68986154032484877231
Autor:
Der-Cherng Liang, Ming-Chun Chiu, Tung-Huei Lin, Yu-Shu Shih, Chein-Fuang Huang, Ming-Chung Kuo, Ying-Jung Huang, Sung-Tzu Liang, Lee-Yung Shih, Shu-Chun Tsai
Supplementary Figure S1 and Tables S1-3. Figure S1. Frequencies and distribution of co-operating mutations in RUNX1 mutationpositive patients. Table S1. Comparison of clinicohematological characteristics according to the biological activities of RUNX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27e6ea4418272604a22f5910130ebe7e
https://doi.org/10.1158/1078-0432.22455140.v1
https://doi.org/10.1158/1078-0432.22455140.v1
Autor:
Der-Cherng Liang, Ming-Chun Chiu, Tung-Huei Lin, Yu-Shu Shih, Chein-Fuang Huang, Ming-Chung Kuo, Ying-Jung Huang, Sung-Tzu Liang, Lee-Yung Shih, Shu-Chun Tsai
Purpose: Transcription factor RUNX1 is essential for normal hematopoiesis. High mutation frequencies of RUNX1 gene in chronic myelomonocytic leukemia (CMML) and myelodysplastic syndromes (MDS) have been described, whereas the biologic significances o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd03bb25b98934bd954dbbef9f9399c
https://doi.org/10.1158/1078-0432.c.6522935.v1
https://doi.org/10.1158/1078-0432.c.6522935.v1
Autor:
Hsiao-Wen Kao, Ming-Chung Kuo, Ying-Jung Huang, Hung Chang, Shu-Fen Hu, Chein-Fuang Huang, Yu-Shin Hung, Tung-Liang Lin, Che-Wei Ou, Ming-Yu Lien, Jin-Hou Wu, Chih-Cheng Chen, Lee-Yung Shih
Publikováno v:
Cancers; Volume 14; Issue 24; Pages: 6205
Locked nucleic acid quantitative Real-Time PCR (LNA-qPCR) for IDH1/2 mutations in AML measurable residual disease (MRD) detection is rarely reported. LNA-qPCR was applied to quantify IDH1/2 mutants MRD kinetics in bone marrow from 88 IDH1/2-mutated A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d06438146fe842a3639db0368af910
Autor:
Yasunobu Nagata, Chang-Liang Lai, Masashi Sanada, Kenichi Chiba, Satoru Miyano, Yuichi Shiraishi, Seishi Ogawa, Ming-Chung Kuo, Lee-Yung Shih, Hiroko Tanaka, Chein-Fuang Huang, Jin-Hou Wu, Der-Cherng Liang, Tung-Huei Lin, Tung-Liang Lin, En-Hui Lee, Hsiao-Wen Kao, Yu-Shu Shih, Yusuke Okuno
Publikováno v:
Haematologica. 99:28-36
Somatic mutations of TET2, IDH1, and IDH2 have been described in myelodysplastic syndrome. The impact of these mutations on outcome of myelodysplastic syndrome and their progression to secondary acute myeloid leukemia remains unclear. Mutation status
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f033569e8b332abe655e9a6a6fd9e20a
https://doi.org/10.3324/haematol.2013.091249
https://doi.org/10.3324/haematol.2013.091249
Autor:
Po-Nan Wang, Ming-Chung Kuo, Tzung-Chih Tang, Po Dunn, Jin-Hou Wu, Chein-Fuang Huang, Lee-Yung Shih, Tung-Liang Lin
Publikováno v:
Clinical Cancer Research. 11:1821-1826
Purpose: We aimed to assess the role of CEBPα mutations in the progression of myelodysplastic syndrome (MDS) to acute myelogenous leukemia (AML) and their cooperating mutations. Experimental Design: Mutational analysis of CEBPα with direct sequenci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfbf5f8f57aa4f748e7d13361d4ce03f
https://doi.org/10.1158/1078-0432.ccr-04-1932
https://doi.org/10.1158/1078-0432.ccr-04-1932
Autor:
Chein-Fuang Huang, Tung-Liang Lin, Lee-Yung Shih, Jin-Hou Wu, Ming-Chung Kuo, Po-Nan Wang, Po Dunn
Publikováno v:
Cancer. 101:989-998
BACKGROUND The prognostic significance of internal tandem duplication (ITD) of the fms-like tyrosine kinase 3 gene (FLT3) for patients with myelodysplastic syndrome (MDS) is not clearly defined. In the current study, the authors sought to assess the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010f43ecbd7d6c7cd49c48cf27493930
https://doi.org/10.1002/cncr.20440
https://doi.org/10.1002/cncr.20440
Autor:
Jin-Hou Wu, Shih Ly, Po-Nan Wang, Tung-Liang Lin, Ming-Chung Kuo, Chung-Chih Tang, Po Dunn, Meng-Chu Chou, Chein-Fuang Huang
Publikováno v:
Clinical Cancer Research. 10:1326-1332
Purpose: We analyzed Asp835 mutations of FLT3 on paired marrow samples at diagnosis and relapse from 120 adult patients with de novo acute myeloid leukemia (AML) to determine the role of FLT3 Asp835 mutation in the relapse of AML. Experimental Design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d06b08e427b686e68ff7a9e83a52f1be
https://doi.org/10.1158/1078-0432.ccr-0835-03
https://doi.org/10.1158/1078-0432.ccr-0835-03