Diphenhydramine induces melanoma cell apoptosis by suppressing STAT3/MCL-1 survival signaling and retards B16-F10 melanoma growth in vivo

Autor: Chi-Hung R. Or, Cheesang Ho, Hong-Lin Su, Wee-Chyan Lee, Shu-Yi Yang, Chia-Che Chang

Publikováno v: Oncology Reports. 36:3465-3471

Melanoma is the most aggressive skin malignancy with a high rate of mortality and is frequently refractory to many therapeutics, thus demanding the discovery of novel effective anti-melanoma agents. Diphenhydramine (DPH) is an H1 histamine receptor a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95533a2f5ef4d9d44509207fda1dc88a
https://doi.org/10.3892/or.2016.5201

Obatoclax, a Pan-BCL-2 Inhibitor, Targets Cyclin D1 for Degradation to Induce Antiproliferation in Human Colorectal Carcinoma Cells

Autor: Cheesang Ho, Yachu Chang, Wei-Cheng Lin, Chang-Po Huang, Muk-Wing Cheung, Wee-Chyan Lee, Chi-Hung R. Or, Chia-Che Chang, Hong-Lin Su

Publikováno v: International Journal of Molecular Sciences, Vol 18, Iss 1, p 44 (2016)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 18; Issue 1; Pages: 44

Colorectal cancer is the third most common cancer worldwide. Aberrant overexpression of antiapoptotic BCL-2 (B-cell lymphoma 2) family proteins is closely linked to tumorigenesis and poor prognosis in colorectal cancer. Obatoclax is an inhibitor targ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::865a098cd21ca96187d97b09dabbd9b2
http://www.mdpi.com/1422-0067/18/1/44

Obatoclax, a Pan-BCL-2 Inhibitor, Targets Cyclin D1 for Degradation to Induce Antiproliferation in Human Colorectal Carcinoma Cells.

Autor: Chi-Hung R. Or, Yachu Chang, Wei-Cheng Lin, Wee-Chyan Lee, Hong-Lin Su, Muk-Wing Cheung, Chang-Po Huang, Cheesang Ho, Chia-Che Chang

Publikováno v: International Journal of Molecular Sciences; Jan2017, Vol. 18 Issue 1, p44, 16p, 3 Diagrams, 3 Graphs

New device for Pentax-Airway Scope in pediatric intubation

Autor: Cheesang Ho

Publikováno v: Acta Anaesthesiologica Taiwanica. 48:178-179

The PBLADE which is a component used with Pentax-Airway Scope (AWS) has only one size that is essentially for use in adults. It cannot be used in children and neonates. We have made a new device to fit the Pentax-AWS for use in children and neonates.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cf2a3ddfec8429aa79854d4c3d727b9
https://doi.org/10.1016/j.aat.2010.04.001