Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Cheen Fei Chin"'
Autor:
Cheen Fei Chin, Dwight L.A. Galam, Liang Gao, Bryan C. Tan, Bernice H. Wong, Geok-Lin Chua, Randy Y.J. Loke, Yen Ching Lim, Markus R. Wenk, Miao-Shan Lim, Wei-Qiang Leow, George B.B. Goh, Federico Torta, David L. Silver
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 17 (2023)
The liver has a high demand for phosphatidylcholine (PC), particularly in overnutrition, where reduced phospholipid levels have been implicated in the development of nonalcoholic fatty liver disease (NAFLD). Whether other pathways exist in addition t
Externí odkaz:
https://doaj.org/article/65986795ef3e486290872e1e79aa32e1
Autor:
Randy Y.J. Loke, Cheen Fei Chin, Gao Liang, Bernice H. Wong, Dwight L.A. Galam, Bryan C. Tan, Geok-Lin Chua, Shintaro Minegishi, Norihiko Morisawa, Iulia Sidorov, Bram Heijs, Jens Titze, Markus R. Wenk, Federico Torta, David L. Silver
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 8, Pp 100416- (2023)
Acute kidney injury (AKI) is a global public health concern with high mortality and morbidity. In ischemic–reperfusion injury (IRI), a main cause of AKI, the brush border membrane of S3 proximal tubules (PT) is lost to the tubular lumen. How injure
Externí odkaz:
https://doaj.org/article/672d13e383c743709655a740077d87eb
Autor:
Jia Pei Chan, Bernice H Wong, Cheen Fei Chin, Dwight L A Galam, Juat Chin Foo, Loo Chin Wong, Sujoy Ghosh, Markus R Wenk, Amaury Cazenave-Gassiot, David L Silver
Publikováno v:
PLoS Biology, Vol 16, Iss 8, p e2006443 (2018)
Brain development requires a massive increase in brain lipogenesis and accretion of the essential omega-3 fatty acid docosahexaenoic acid (DHA). Brain acquisition of DHA is primarily mediated by the transporter Major Facilitator Superfamily Domain co
Externí odkaz:
https://doaj.org/article/544aa20fbc204aaf8689028e21a55a66
Autor:
Cheen Fei Chin, Kaiquan Tan, Masayuki Onishi, YuanYuan Chew, Beryl Augustine, Wei Ren Lee, Foong May Yeong
Publikováno v:
PLoS Genetics, Vol 12, Iss 7, p e1006195 (2016)
Cytokinesis requires the spatio-temporal coordination of membrane deposition and primary septum (PS) formation at the division site to drive acto-myosin ring (AMR) constriction. It has been demonstrated that AMR constriction invariably occurs only af
Externí odkaz:
https://doaj.org/article/66804f98bab84091a3efdfac91aa7f37
Autor:
Menglan He, Alvin C. Y. Kuk, Mei Ding, Cheen Fei Chin, Dwight L.A. Galam, Jie Min Nah, Bryan C. Tan, Hui Li Yeo, Geok Lin Chua, Peter I. Benke, Markus R. Wenk, Lena Ho, Federico Torta, David L. Silver
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(40)
The lysosome is central to the degradation of proteins, carbohydrates, and lipids and their salvage back to the cytosol for reutilization. Lysosomal transporters for amino acids, sugars, and cholesterol have been identified, and the metabolic fates o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97e8b394db013b78b902bbfceb0c73da
https://pubmed.ncbi.nlm.nih.gov/36161949
https://pubmed.ncbi.nlm.nih.gov/36161949
Autor:
Geok-Lin Chua, Bryan C. Tan, Randy Y. J. Loke, Menglan He, Cheen-Fei Chin, Bernice H. Wong, Alvin C. Y. Kuk, Mei Ding, Markus R. Wenk, Lan Guan, Federico Torta, David L. Silver
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Major Facilitator Superfamily Domain containing 2a (Mfsd2a) is a sodium-dependent lysophosphatidylcholine (LPC) transporter expressed at the blood–brain barrier that constitutes the main pathway by which the brain obtains omega-3 fatty acids, such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9135013a5992d6a112700ae4b817be17
https://doi.org/10.1073/pnas.2215290120
https://doi.org/10.1073/pnas.2215290120
Autor:
Pasquale Striano, Ehsan Ghayoor Karimiani, Vincenzo Salpietro, Hao Fan, Yasser Sabr, Cheen Fei Chin, Emer O'Connor, Henry Houlden, Saima Riazuddin, Hessa S. Alsaif, David L. Silver, Elena L. Dadali, Yalda Jamshidi, Artem Borovikov, Galina Baydakova, F. A. Konovalov, Reza Maroofian, Fowzan S. Alkuraya, Mehran Beiraghi Toosi, M. Chiara Manzini, Mariasavina Severino, Federico Zara, Alvin Kuk, Abdullah Alfaifi, Ekaterina R. Lozier, Farah Ashrafzadeh, Marcello Scala, Geok Lin Chua, Mohammad Doosti, Sheikh Riazuddin
Publikováno v:
Eur J Hum Genet
Web of Science
Web of Science
Major Facilitator Superfamily Domain containing 2a (MFSD2A) is an essential endothelial lipid transporter at the blood-brain barrier. Biallelic variants affecting function in MFSD2A cause autosomal recessive primary microcephaly 15 (MCPH15, OMIM# 616
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::104a16a24c7509dff09518ffcca26834
https://doi.org/10.1038/s41431-020-0669-x
https://doi.org/10.1038/s41431-020-0669-x
Publikováno v:
Pedagogies: An International Journal. 15:83-105
Student engagement in large Life Sciences classes can be problematic, especially with the course work done outside formal class contact hours. To enhance student engagement with the content outside...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2468542a128cebb99096c5e76681f15b
https://doi.org/10.1080/1554480x.2019.1684924
https://doi.org/10.1080/1554480x.2019.1684924
Autor:
Shi Yin Er, Vishnu Priyanka Reddy Chichili, Yi Ting Zhou, Cheen Fei Chin, Foong May Yeong, Srihari Shankar, Boon Chuan Low, Catherine Qiurong Pan, Ti Weng Chew, J. Sivaraman, Chacko Jobichen
Publikováno v:
Proc Natl Acad Sci U S A
Spatiotemporal regulation of signaling cascades is crucial for various biological pathways, under the control of a range of scaffolding proteins. The BNIP-2 and Cdc42GAP Homology (BCH) domain is a highly conserved module that targets small GTPases an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adcdca25de7f65925987c9886963cff8
https://doi.org/10.1073/pnas.2014242118
https://doi.org/10.1073/pnas.2014242118
Autor:
Menglan He, Kuk, Mei Ding, Cheen Fei Chin, Galam, Dwight L. A., Jie Min Nah, Tan, Bryan C., Hui Li Yeo, Geok Lin Chua, Benke, Peter I., Wenk, Markus R., Lena Ho, Torta, Federico, Silver, David L.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 10/4/2022, Vol. 119 Issue 40, p1-9, 9p