A unique interplay of access and selection shapes peritoneal metastasis evolution in colorectal cancer.

Autor: Wassenaar EC; Department of Surgery, St. Antonius Hospital, Nieuwegein, the Netherlands.; Department of Surgical Oncology, Laboratory Translational Oncology, University Medical Center Utrecht, Utrecht, the Netherlands., Gorelick AN; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Center for Systems Biology, Massachusetts General Hospital Research Institute and Harvard Medical School, Boston, MA, USA., Hung WT; Center for Systems Biology, Massachusetts General Hospital Research Institute and Harvard Medical School, Boston, MA, USA.; Present address: Graduate Institute of Medical Genomics and Proteomics, National Taiwan University, Taipei, Taiwan., Cheek DM; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Center for Systems Biology, Massachusetts General Hospital Research Institute and Harvard Medical School, Boston, MA, USA., Kucukkose E; Department of Surgical Oncology, Laboratory Translational Oncology, University Medical Center Utrecht, Utrecht, the Netherlands., Lee IH; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Center for Systems Biology, Massachusetts General Hospital Research Institute and Harvard Medical School, Boston, MA, USA., Blohmer M; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Center for Systems Biology, Massachusetts General Hospital Research Institute and Harvard Medical School, Boston, MA, USA.; Charité - Universitätsmedizin Berlin, Berlin, Germany., Degner S; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Center for Systems Biology, Massachusetts General Hospital Research Institute and Harvard Medical School, Boston, MA, USA., Giunta P; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Center for Systems Biology, Massachusetts General Hospital Research Institute and Harvard Medical School, Boston, MA, USA., Wiezer RM; Department of Surgery, St. Antonius Hospital, Nieuwegein, the Netherlands., Raicu MG; Department of Pathology, St. Antonius Hospital, Nieuwegein, the Netherlands.; Oncode Institute, Hubrecht Institute-KNAW (Royal Academy of Arts and Sciences) and University Medical Centre Utrecht, Utrecht, the Netherlands., Ubink I; Department of Surgical Oncology, Laboratory Translational Oncology, University Medical Center Utrecht, Utrecht, the Netherlands., Klaasen SJ; Oncode Institute, Hubrecht Institute-KNAW (Royal Academy of Arts and Sciences) and University Medical Centre Utrecht, Utrecht, the Netherlands., Lansu N; Oncode Institute, Hubrecht Institute-KNAW (Royal Academy of Arts and Sciences) and University Medical Centre Utrecht, Utrecht, the Netherlands., Watson EV; University of Massachusetts Medical School, Worcester, MA, USA., Corcoran RB; Division of Hematology and Oncology, Department of Medicine, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Boland G; Division of Surgical Oncology, Department of Surgery, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA.; Krantz Family Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA., Getz G; Krantz Family Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA., Kops GJ; Oncode Institute, Hubrecht Institute-KNAW (Royal Academy of Arts and Sciences) and University Medical Centre Utrecht, Utrecht, the Netherlands., Juric D; Krantz Family Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.; Termeer Center for Targeted Therapies, Massachusetts General Hospital, Boston, MA, USA., Lennerz JK; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA., Boerma D; Department of Surgery, St. Antonius Hospital, Nieuwegein, the Netherlands., Kranenburg O; Department of Surgical Oncology, Laboratory Translational Oncology, University Medical Center Utrecht, Utrecht, the Netherlands., Naxerova K; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Center for Systems Biology, Massachusetts General Hospital Research Institute and Harvard Medical School, Boston, MA, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Sep 27. Date of Electronic Publication: 2024 Sep 27.