Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Chee-Gun Lee"'
Autor:
Roberto Colangeli, Danica Helb, Catherine Vilchèze, Manzour Hernando Hazbón, Chee-Gun Lee, Hassan Safi, Brendan Sayers, Irene Sardone, Marcus B Jones, Robert D Fleischmann, Scott N Peterson, William R Jacobs, David Alland
Publikováno v:
PLoS Pathogens, Vol 3, Iss 6, p e87 (2007)
Multi-drug tolerance is a key phenotypic property that complicates the sterilization of mammals infected with Mycobacterium tuberculosis. Previous studies have established that iniBAC, an operon that confers multi-drug tolerance to M. bovis BCG throu
Externí odkaz:
https://doaj.org/article/8cae0df6b9ae402b9e8ce8f5476abd8b
Autor:
Andrew M. Parrott, Helene Z. Hill, Inger Tappin, Bin Lu, Robert Lim, Stella Chung, Anita Antes, Carolyn K. Suzuki, Chee-Gun Lee
Publikováno v:
Nucleic Acids Research
Mammalian mitochondria contain full-length genome and a single-stranded 7S DNA. Although the copy number of mitochondrial DNA (mtDNA) varies depending on the cell type and also in response to diverse environmental stresses, our understanding of how m
Autor:
Seung-Won Park, Andrew M. Parrott, Chee-Gun Lee, Yongkyu Park, David T. Fritz, Michael B. Mathews
Publikováno v:
Nucleic Acids Research
Topoisomerase IIalpha interacts with numerous nuclear factors, through which it is engaged in diverse nuclear events such as DNA replication, transcription and the formation or maintenance of heterochromatin. We previously reported that topoisomerase
Autor:
Nihal Altan-Bonnet, Mohammed Khaleduzzaman, Chee-Gun Lee, Quan Li, Cindy J. Arrigo, Hong Li, Deyu Guan, Andrew M. Parrott, Michael B. Mathews, Tsafi Pe'ery
Publikováno v:
Molecular and Cellular Biology. 28:4629-4641
Nuclear factor 90 (NF90) and its C-terminally extended isoform, NF110, have been isolated as DNA- and RNA-binding proteins together with the less-studied protein NF45. These complexes have been implicated in gene regulation, but little is known about
Publikováno v:
Cell Cycle. 3:636-645
Topoisomerase IIalpha plays essential roles in chromosome segregation. However, it is not well understood how topoisomerase IIalpha exerts its function during mitosis. In this report, we find that topoisomerase IIalpha forms a multisubunit complex, n
Autor:
Chee-Gun Lee
Publikováno v:
Journal of Biological Chemistry. 277:39679-39683
In this report, I describe the co-purification of a novel 70-kDa RNA helicase (RH70) and U1snRNP through six column steps. Peptide sequence analysis by mass spectrometry and Edman degradation revealed that RH70 is the previously reported DDX17. Bioch
Autor:
Chee-Gun Lee, Jun-Qi Yang, Minoru Satoh, Hanno B. Richards, Krista M. Behney, Ram Singh, Hideo Yoshida, Victoria M. Shaheen, Westley H. Reeves
Publikováno v:
Arthritis & Rheumatism. 46:2235-2244
Lupus is an autoimmune disorder of protean manifestations thought to result from both hereditary immunoregulatory defects and poorly characterized environmental factors such as ultraviolet radiation or chemicals (1–3). Multiple genetic loci contrib
Publikováno v:
Journal of Biological Chemistry. 276:40389-40395
Covalent attachment of SUMO-1 to Mdm2 requires the activation of a heterodimeric Aos1-Uba2 enzyme (ubiquitin-activating enzyme (E1)) followed by the conjugation of Sumo-1 to Mdm2 by Ubc9, a protein with a strong sequence similarity to ubiquitin carri
Autor:
Hong Li, Chee-Gun Lee, Fatah Kashanchi, Paul Lambert, Cynthia de la Fuente, John D. Wade, Longwen Deng, Peng Fu, Lai Wang, Robert J. Donnelly
Publikováno v:
Virology. 277:278-295
The HIV-1 Tat protein is required for viral replication and is a potent stimulator of viral transcription. Although Tat has been extensively studied in various reductive paradigms, to date there is little information as to how this activator mediates
Publikováno v:
Cell. 101:753-762
Mdm2 is an E3 ubiquitin ligase for the p53 tumor suppressor protein. We demonstrate that Mdm2 is conjugated with SUMO-1 (sumoylated) at Lys-446, which is located within the RING finger domain and plays a critical role in Mdm2 self-ubiquitination. Whe