Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Chee Wun, How"'
Autor:
Jian Sheng Loh, Wen Qi Mak, Li Kar Stella Tan, Chu Xin Ng, Hong Hao Chan, Shiau Hueh Yeow, Jhi Biau Foo, Yong Sze Ong, Chee Wun How, Kooi Yeong Khaw
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-53 (2024)
Abstract The human gastrointestinal tract is populated with a diverse microbial community. The vast genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every aspect of human biology, including health maintenance, de
Externí odkaz:
https://doaj.org/article/699402e597a844858e3779ff9c622ceb
Revisiting the concept of incretin and enteroendocrine L-cells as type 2 diabetes mellitus treatment
Publikováno v:
Pharmacological Research, Vol 180, Iss , Pp 106237- (2022)
The significant growth in type 2 diabetes mellitus (T2DM) prevalence strikes a common threat to the healthcare and economic systems globally. Despite the availability of several anti-hyperglycaemic agents in the market, none can offer T2DM remission.
Externí odkaz:
https://doaj.org/article/9c3087bb488145d5b4aa59b0ebdf53c5
Autor:
Chee Wun How, Siew Li Teoh, Jian Sheng Loh, Stella Li Kar Tan, Jhi Biau Foo, Hui Suan Ng, Stephenie Yoke Wei Wong, Yong Sze Ong
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The conventional concept of using nanocarriers to deliver chemotherapeutic drugs has advanced to accommodate additional diagnostic capability. Nanotheranostic agents (NTA), combining both treatment and diagnostic tools, are an ideal example of engine
Externí odkaz:
https://doaj.org/article/5d835205d4dd412ebbfa52dd3bb8fea0
Autor:
Wei Qing Lim, Kie Hoon Michelle Luk, Kah Yee Lee, Nasuha Nurul, Sin Jade Loh, Zhen Xiong Yeow, Qi Xuan Wong, Qi Hao Daniel Looi, Pan Pan Chong, Chee Wun How, Sharina Hamzah, Jhi Biau Foo
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1216 (2023)
Neurodegenerative diseases are critical in the healthcare system as patients suffer from progressive diseases despite currently available drug management. Indeed, the growing ageing population will burden the country’s healthcare system and the car
Externí odkaz:
https://doaj.org/article/bd3eaa7e9f154f74b055ff6293b1df76
Publikováno v:
Pharmaceuticals, Vol 16, Iss 3, p 451 (2023)
Lung cancer is the most common cause of cancer-related deaths. Lung cancers can be classified as small-cell (SCLC) or non-small cell (NSCLC). About 84% of all lung cancers are NSCLC and about 16% are SCLC. For the past few years, there have been a lo
Externí odkaz:
https://doaj.org/article/2712284a8b0149889fd4d6692ae9110a
Autor:
Jhi Biau Foo, Qi Hao Looi, Pan Pan Chong, Nur Hidayah Hassan, Genieve Ee Chia Yeo, Chiew Yong Ng, Benson Koh, Chee Wun How, Sau Har Lee, Jia Xian Law
Publikováno v:
Stem Cells International, Vol 2021 (2021)
Cell therapy involves the transplantation of human cells to replace or repair the damaged tissues and modulate the mechanisms underlying disease initiation and progression in the body. Nowadays, many different types of cell-based therapy are develope
Externí odkaz:
https://doaj.org/article/54f8f3ba776e419a9b623106a6f8b98b
Autor:
Seng Kar Yap, Kian Leong Tan, Nor Yasmin Abd Rahaman, Nur Fazila Saulol Hamid, Der Jiun Ooi, Yin Sim Tor, Qi Hao Daniel Looi, Li Kar Stella Tan, Chee Wun How, Jhi Biau Foo
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 649 (2022)
Human umbilical cord mesenchymal stem cell-derived small extracellular vesicle (hUC-MSCs-sEVs) therapy has shown promising results to treat diabetes mellitus in preclinical studies. However, the dosage of MSCs-sEVs in animal studies, up to 10 mg/kg,
Externí odkaz:
https://doaj.org/article/0e047fc7e0af400aa93563fd3a0f2391
Autor:
Jhi Biau Foo, Qi Hao Looi, Chee Wun How, Sau Har Lee, Maimonah Eissa Al-Masawa, Pei Pei Chong, Jia Xian Law
Publikováno v:
Pharmaceuticals, Vol 14, Iss 11, p 1093 (2021)
Exosomes are the small extracellular vesicles secreted by cells for intercellular communication. Exosomes are rich in therapeutic cargos such as microRNA (miRNA), long non-coding RNA (lncRNA), small interfering RNA (siRNA), DNA, protein, and lipids.
Externí odkaz:
https://doaj.org/article/95cdac218bfa4f508c1a5971d26fbc7d
Autor:
Pornwasu Pongtheerawan, Christopher Chun Sing Wong, Chee Wun How, May Lee Low, Yin Sim Tor, Kian Leong Tan, Jhi Biau Foo, Chee Hong Leong, Yong Sze Ong, Sathiavani Arikrishnan, Krystal U Ling Lim, Jian Sheng Loh, Zheng Yang Lee
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 22:1159-1170
Background: Copper complex has been gaining much attention in anticancer research as a targeted agent since cancer cells uptake more copper than non-cancerous cells. Our group synthesised a ternary copper complex, which is composed of 1,10-phenanthro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63815334a64897c37f8228f59d741611
https://doi.org/10.2174/1871520621666210726132543
https://doi.org/10.2174/1871520621666210726132543
Autor:
Chaw Yee Beh, Abdullah Rasedee, Gayathri Thevi Selvarajah, Latifah Saiful Yazan, Abdul Rahman Omar, Jia Ning Foong, Chee Wun How, Jhi Biau Foo
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0219285 (2019)
Nanomedicine is an emerging area in the medical field, particularly in the treatment of cancers. Nanostructured lipid carrier (NLC) was shown to be a good nanoparticulated carrier for the delivery of tamoxifen (TAM). In this study, the tamoxifen-load
Externí odkaz:
https://doaj.org/article/bff6e97f14c44954b94a606bceb35834