Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Chee Sin Tay"'
Autor:
Amanda E Garza, Gordon H. Williams, Luminita H. Pojoga, Chee Sin Tay, Jian Yao Wong, Shadi K Gholami, Jose R. Romero, Ezgi Caliskan Guzelce, Jessica Lee, Gail K. Adler, Eleanor Zagoren, Stephen A. Maris
Publikováno v:
Journal of Endocrinology. 252:1-13
Inconsistencies have been reported on the effect of sex on aldosterone (ALDO) levels leading to clinical confusion. The reasons for these inconsistencies are uncertain but include estrogen and/or its receptor modulating target gene responses to miner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57e03fdd389bb0040a4c3b8023458165
https://doi.org/10.1530/joe-21-0126
https://doi.org/10.1530/joe-21-0126
Autor:
Luminita H. Pojoga, Chee Sin Tay, Gordon H. Williams, Thitinan Treesaranuwattana, Kelly Yin Han Wong, Jonathan S. Williams, Danielle L Brooks
Publikováno v:
Hypertension
LSD1 (lysine-specific demethylase-1) is an epigenetic regulator of gene transcription. LSD1 risk allele in humans and LSD1 deficiency ( LSD1 +/− ) in mice confer increasing salt-sensitivity of blood pressure with age, which evolves into salt-sensit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec497464c84f171dad2fdc32a6dc90e8
https://doi.org/10.1161/hypertensionaha.119.13821
https://doi.org/10.1161/hypertensionaha.119.13821
Autor:
Stephen A. Maris, Jessica Lee, Shadi K Gholami, Gordon H. Williams, Thitinan Treesaranuwattana, Chee Sin Tay, Danielle L Brooks, Sanjay Ranjit, Gail K. Adler, Luminita H. Pojoga, Jose R. Romero, Amanda E Garza, Ezgi Caliskan Guzelce
Publikováno v:
Endocrinology
The mechanistic target of the rapamycin (mTOR) pathway plays a role in features common to both excess salt/aldosterone and cardiovascular/renal diseases. Dietary sodium can upregulate mTORC1 signaling in cardiac and renal tissue, and the inhibition o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b65a1524358bd69ef07e453602866e4
Autor:
Jose R. Romero, Isis Akemi Katayama, Sanjay Ranjit, Gail K. Adler, Stephen A. Maris, Jian Yao Wong, Chee Sin Tay, Gordon H. Williams, Luminita H. Pojoga, Alicia Rivera, Jia Wei Tan, Kelly Yin Han Wong, Jonathan S. Williams, Jessica Lee, Amanda E Garza, Danielle L Brooks
Publikováno v:
JCI insight. 4(21)
Salt sensitivity of blood pressure (SSBP) and hypertension are common, but the underlying mechanisms remain unclear. Endoplasmic reticulum aminopeptidase 1 (ERAP1) degrades angiotensin II (ANGII). We hypothesized that decreasing ERAP1 increases BP vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a5345366ea95a5aa9ffa35c1a81e3ac
https://pubmed.ncbi.nlm.nih.gov/31740848
https://pubmed.ncbi.nlm.nih.gov/31740848
Autor:
Eleanor Zagoren, Chee Sin Tay, Amanda E Garza, Gordon H. Williams, Jessica Lee, Jose R. Romero, Stephen A. Maris, Gail K. Adler, Luminita H. Pojoga
Publikováno v:
Journal of the Endocrine Society
Statin therapy, which lowers LDL cholesterol, has a profound beneficial cardiovascular (CV) effect. However, some of statins’ CV benefits appear to be independent of decreases in LDL. We showed that statins reduce Aldosterone (ALDO) levels, a key h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4055c8daa6f86432d9d8d4de867472d9
https://doi.org/10.1210/js.2019-sat-356
https://doi.org/10.1210/js.2019-sat-356