Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Chee Pang Ng"'
Autor:
Anders Poulsen, Kee Chuan Goh, Ee Ling Teo, Chee Pang Ng, Stéphanie Blanchard, Evelyn Tan, Wai Chung Ong, Kay Lin Goh, Weiping Deng, Angeline C.-H. Lee, Eric T. Sun, Anthony D. William, Noah Tu, Zahid Bonday
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:2443-2447
A series of alkenyl indazoles were synthesized and evaluated in Aurora kinase enzyme assays. Several promising leads were optimized for selectivity towards Aurora B. Excellent binding affinity and good selectivity were achieved with optimized compoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3804e131a7790015f35bf5b404ddd9ce
https://doi.org/10.1016/j.bmcl.2010.03.018
https://doi.org/10.1016/j.bmcl.2010.03.018
Autor:
Caine Tuck Choy, Leong, Chuan Young, Ng, Choon Kiat, Ong, Chee Pang, Ng, Zeng Shuan, Ma, Thanh Hung, Nguyen, Sun Kuie, Tay, Hung, Huynh
Publikováno v:
Oncogene. 23:5707-5718
We have previously reported the characterization of an estrogen-regulated rat uterine-ovarian-specific complementary DNA (UO-44). To understand the involvement of this protein in the initiation and progression of human ovarian and uterine cancers, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::911695b69b12d2d46e6751ca4cf1cab4
https://doi.org/10.1038/sj.onc.1207754
https://doi.org/10.1038/sj.onc.1207754
Publikováno v:
Canadian Journal of Microbiology. 46:166-170
A key step which involves the cyclization of δ-(L-α-aminoadipyl)-L-cysteinyl-D-valine to the bicyclic ring structure of isopenicillin N in the penicillin and cephalosporin biosynthetic pathway, is catalyzed by isopenicillin N synthase (IPNS). In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13202eb0561259adf58ee9e0be0e7112
https://doi.org/10.1139/w99-127
https://doi.org/10.1139/w99-127
Autor:
Angeline Lee, Evelyn Tan, Kay Lin Goh, Eric T. Sun, Anthony D. William, Wai Chung Ong, Kee Chuan Goh, Weiping Deng, Stéphanie Blanchard, Eeling Teo, Anders Poulsen, Chee Pang Ng, Noah Tu, Zahid Bonday
Publikováno v:
Journal of computer-aided molecular design. 22(12)
The Aurora family of serine/threonine kinases are mitotic regulators involved in centrosome duplication, formation of the bipolar mitotic spindle and the alignment of the chromosomes along the spindle. These proteins are frequently overexpressed in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::575e7486a0fde2742bcb2123c838ef4c
https://pubmed.ncbi.nlm.nih.gov/18574696
https://pubmed.ncbi.nlm.nih.gov/18574696
Autor:
Chye Sun Ong, Chuan Young Ng, Caine Leong, Chee Pang Ng, Choon Kiat Ong, Thi Thanh Tuyen Nguyen, Hung Huynh
Publikováno v:
Endocrinology. 145(10)
We previously identified a novel pregnancy-induced growth inhibitory gene, OKL38. To develop a rat model for further characterization of OKL38’s role in the initiation and progression of breast and ovarian cancer, we now report the cloning and char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41a9be772fd030584d2bb5e202d326f1
https://pubmed.ncbi.nlm.nih.gov/15217983
https://pubmed.ncbi.nlm.nih.gov/15217983
Publikováno v:
International Journal of Oncology.
Combination chemotherapy is increasingly practiced for the treatment of malignant prostate cancers. The aim of this study was to evaluate the in vivo efficacy of combined tamoxifen and quercetin in prostate tumor xenografts. Severe combined immune de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a407242e0f6bbabbc737cbb38a6afa2
https://doi.org/10.3892/ijo.24.5.1297
https://doi.org/10.3892/ijo.24.5.1297
Autor:
Choon Kiat Ong, Siew Kuen Lee, Jia Jing Lee, T. T. Tuyen Nguyen, Chee Pang Ng, Hung Huynh, Caine Leong, Chye Sun Ong, Evelyn Tran
Publikováno v:
Oncology reports. 11(3)
Nasopharyngeal carcinoma is a common cancer in South-East Asia, especially among people of Chinese origin. In this report, we investigate the effects of quercetin on the growth of wild-type and mutant p53 nasopharyngeal carcinoma cell lines, HK1 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20621c1973250c90bb064a489b672992
https://pubmed.ncbi.nlm.nih.gov/14767529
https://pubmed.ncbi.nlm.nih.gov/14767529
Autor:
Caine Tuck Choy Leong, Chuan Young Ng, Chee Pang Ng, Zeng Shuan Ma, Thanh Hung Nguyen, Sun Kuie Tay, Hung Huynh
Publikováno v:
Oncogene. 23:8857-8857
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81a50ce39ca6243e74b656a5df2a4d40
https://doi.org/10.1038/sj.onc.1208155
https://doi.org/10.1038/sj.onc.1208155
Autor:
Choon Kiat Ong1, Chuan Young Ng2, Caine Leong1, Chee Pang Ng1, Keong Tatt Foo2, Puay Hoon Tan3, Hung Huynh1 cmrhth@nccs.com.sg
Publikováno v:
Journal of Biological Chemistry. 1/02/2004, Vol. 279 Issue 1, p743-754. 13p. 10 Color Photographs, 10 Black and White Photographs, 8 Diagrams, 3 Charts, 2 Graphs.