Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Chee Kian Chew"'
Autor:
Megan M. Weivoda, Chee Kian Chew, David G. Monroe, Joshua N. Farr, Elizabeth J. Atkinson, Jennifer R. Geske, Brittany Eckhardt, Brianne Thicke, Ming Ruan, Amanda J. Tweed, Louise K. McCready, Robert A. Rizza, Aleksey Matveyenko, Moustapha Kassem, Thomas Levin Andersen, Adrian Vella, Matthew T. Drake, Bart L. Clarke, Merry Jo Oursler, Sundeep Khosla
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Anti-resorptive bone therapies also inhibit bone formation, as osteoclasts secrete factors that stimulate bone formation by osteoblasts. Here, the authors identify osteoclast-secreted factors that couple bone resorption to bone formation in healthy s
Externí odkaz:
https://doaj.org/article/801d47b97fd94e109d4d6b51b08d8de3
Autor:
Brenda Su Ping Lim, S. Sendhil Velan, Navin Michael, Priya Govindharajulu, Siew Pang Chan, Christiani Jeyakumar Henry, Melvin Khee-Shing Leow, Suresh Anand Sadananthan, Wai Han Hoi, Yingshan Lee, Timothy Peng Lim Quek, Shaikh A K K Abdul Shakoor, Pei Shan Yeo, Yaligar Jadegoud, Daniel Ek Chew, Huiling Liew, Sanjay Kumar Verma, Hui Jen Goh, Rinkoo Dalan, Lijuan Sun, Chee Kian Chew
Publikováno v:
European Journal of Endocrinology
Objective Brown adipose tissue (BAT) controls metabolic rate through thermogenesis. As its regulatory factors during the transition from hyperthyroidism to euthyroidism are not well established, our study investigated the relationships between suprac
Autor:
Bart L. Clarke, Chee Kian Chew
Publikováno v:
Maturitas. 111:61-68
Peak bone mass is the maximum bone mass that accrues during growth and development. Consolidation of peak bone mass normally occurs during early adulthood. Low peak bone mass results from failure to achieve peak bone mass genetic potential, primarily
Autor:
Brianne S Thicke, Ming Ruan, Aleksey V. Matveyenko, Jennifer R. Geske, Merry Jo Oursler, Amanda J Tweed, David G. Monroe, Bart L. Clarke, Brittany A. Eckhardt, Thomas Levin Andersen, Joshua N. Farr, Chee Kian Chew, Matthew T. Drake, Sundeep Khosla, Adrian Vella, Robert A. Rizza, Elizabeth J. Atkinson, Moustapha Kassem, Louise K. McCready, Megan M. Weivoda
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Weivoda, M M, Chew, C K, Monroe, D G, Farr, J N, Atkinson, E J, Geske, J R, Eckhardt, B, Thicke, B, Ruan, M, Tweed, A J, McCready, L K, Rizza, R A, Matveyenko, A, Kassem, M, Andersen, T L, Vella, A, Drake, M T, Clarke, B L, Oursler, M J & Khosla, S 2020, ' Identification of osteoclast-osteoblast coupling factors in humans reveals links between bone and energy metabolism ', Nature Communications, vol. 11, 87 . https://doi.org/10.1038/s41467-019-14003-6
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Weivoda, M M, Chew, C K, Monroe, D G, Farr, J N, Atkinson, E J, Geske, J R, Eckhardt, B, Thicke, B, Ruan, M, Tweed, A J, McCready, L K, Rizza, R A, Matveyenko, A, Kassem, M, Andersen, T L, Vella, A, Drake, M T, Clarke, B L, Oursler, M J & Khosla, S 2020, ' Identification of osteoclast-osteoblast coupling factors in humans reveals links between bone and energy metabolism ', Nature Communications, vol. 11, 87 . https://doi.org/10.1038/s41467-019-14003-6
Bone remodeling consists of resorption by osteoclasts followed by formation by osteoblasts, and osteoclasts are a source of bone formation-stimulating factors. Here we utilize osteoclast ablation by denosumab (DMAb) and RNA-sequencing of bone biopsie
Autor:
Lijuan Sun, Hui Jen Goh, Verma, Sanjay, Govindharajulu, Priya, Sadananthan, Suresh Anand, Michael, Navin, Jadegoud, Yaligar, Henry, Christiani Jeyakumar, Velan, S. Sendhil, Pei Shan Yeo, Yingshan Lee, Brenda Su Ping Lim, Huiling Liew, Chee Kian Chew, Peng Lim Quek, Timothy, Abdul Shakoor, Shaikh A. K. K., Wai Han Hoi, Siew Pang Chan, Ek Chew, Daniel, Dalan, Rinkoo
Publikováno v:
European Journal of Endocrinology; Oct2021, Vol. 185 Issue 4, p553-563, 11p
Autor:
Bart L. Clarke, Chee Kian Chew
Publikováno v:
Endocrinology and metabolism clinics of North America. 46(3)
Laboratory biochemical testing is critical to the clinical understanding of bone disorders. Patients with skeletal diseases have underlying themes in their pathophysiology that would be impossible to detect without biochemical assessment of serum and
Autor:
Chee Kian Chew
Publikováno v:
Endocrine Practice. 25:280
Autor:
Bart L. Clarke, Chee Kian Chew
Publikováno v:
Maturitas. 97
The treatment of osteoporosis is generally either by inhibition of bone resorption with antiresorptive agents or by stimulation of bone formation with anabolic agents. Currently, teriparatide (recombinant human parathyroid hormone 1-34 [rhPTH (1-34)]