Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Chee Howe Wong"'
Autor:
Ern Yu Tan, Zhe Li, Yuanyuan Qiao, K. M. Karuturi, Yibin Kang, S T Lee, Dave S.B. Hoon, Peiyong Guan, Qiang Yu, K. Huynh, Chee Howe Wong, J. Wang, Jun Li, Xia Jiang, Mengling Feng, Yunzhou Wei
Publikováno v:
Proceedings of the National Academy of Sciences. 110:11121-11126
Efforts to improve the clinical outcome of highly aggressive triple-negative breast cancer (TNBC) have been hindered by the lack of effective targeted therapies. Thus, it is important to identify the specific gene targets/pathways driving the invasiv
Publikováno v:
Oncogene. 30:2242-2251
The c-Myc transcription factor activates a cascade of downstream targets to form a complex transcriptional program that ultimately leads to cellular transformation. Although a large number of protein-encoding genes as well as non-coding RNAs were ide
Publikováno v:
Biomedical Optics Express
Focal Modulation Microscopy (FMM) is a single-photon excitation fluorescence microscopy technique which effectively rejects the out-of-focus fluorescence background that arises when imaging deep inside biological tissues. Here, we report on the imple
Publikováno v:
Oncogene. 33(10)
Aberrant regulation of the pRB/E2F1 pathway has been invariably linked to inappropriate proliferation and/apoptosis in human cancers. Therefore, understanding the intricacies of the signaling pathway and identification of novel E2F1 targets involved
Publikováno v:
Biomedical Optics and 3-D Imaging.
We have developed a focal modulation microscope for real-time florescence imaging of thick tissues. Fluorescence lifetime images and intensity images can be obtained in the same time.
Publikováno v:
Applied optics. 48(17)
Focal modulation microscopy (FMM) is an emerging microscopy technique for fluorescence imaging of thick biological tissue in vivo. A spatial phase modulator is a critical component whose characteristics have a significant impact on the performance of
Publikováno v:
Advances in Imaging.
Spatial phase modulation in the excitation light path is the key to generate intensity modulation in focal modulation microscopy. A simple spatial phase modulator is designed to enhance the signal stability and image quality.
Publikováno v:
ResearcherID
Structured illumination microscopy is a new technique which delivers optical sectioning capability. As a widefield microscopy technique, structured illumination has improved imaging rate over scanning type optical sectioning microscope as it only req
Publikováno v:
Optics Letters. 35:1804
Focal modulation microscopy is an emerging fluorescence microscopy technique for in vivo imaging of thick biological tissues. Here, we present a theoretical study to assess its performance. The scalar diffraction theory is combined with Monte Carlo s
Publikováno v:
ResearcherID
We report a novel light microscopy method for high resolution molecular imaging of thick biological tissues with one photon excited fluorescence. Effective optical sectioning and diffraction limited spatial resolution are achieved when imaging deep i