Zobrazeno 1 - 10
of 118
pro vyhledávání: '"CheMyong Ko"'
Autor:
Christian Secchi, Martina Belli, Tracy N. H. Harrison, Joseph Swift, CheMyong Ko, Antoni J. Duleba, Dwayne Stupack, R. Jeffrey Chang, Shunichi Shimasaki
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Background In the ovarian follicle, the Theca Cells (TCs) have two main functions: preserving morphological integrity and, importantly, secreting steroid androgen hormones. TCs express the essential enzyme 17α-hydroxylase/17,20-desmolase (C
Externí odkaz:
https://doaj.org/article/b568a61ec9894bec9bca17f2184d8b18
Autor:
Penghao Sun, Hongliang Wang, Lingyun Liu, Kaimin Guo, Xian Li, Yin Cao, Chemyong Ko, Zi-Jian Lan, Zhenmin Lei
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
KRAS plays critical roles in regulating a range of normal cellular events as well as pathological processes in many tissues mediated through a variety of signaling pathways, including ERK1/2 and AKT signaling, in a cell-, context- and development-dep
Externí odkaz:
https://doaj.org/article/96df947e8b4541fbbc7b74bc721ca502
Autor:
Somang Lee-Thacker, Hayce Jeon, Yohan Choi, Ichiro Taniuchi, Takeshi Takarada, Yukio Yoneda, CheMyong Ko, Misung Jo
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Abstract Core Binding Factors (CBFs) are a small group of heterodimeric transcription factor complexes composed of DNA binding proteins, RUNXs, and a non-DNA binding protein, CBFB. The LH surge increases the expression of Runx1 and Runx2 in ovulatory
Externí odkaz:
https://doaj.org/article/3d5f1b8574d942ac9a1a967e2817153e
Autor:
Do-Hyun Kim, Hong-Jai Park, Hyeon-Soo Park, Jae-Ung Lee, CheMyong Ko, Myung Chan Gye, Je-Min Choi
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 4, Pp 1-9 (2019)
Autoimmune disease: the importance of estrogen Estrogen signaling may play a crucial role in mediating autoimmune responses and preventing diseases such as rheumatoid arthritis. Estrogen plays vital roles in the female endocrine and reproductive syst
Externí odkaz:
https://doaj.org/article/d230eeb9d44a4fc2938f0eefdc0632f8
Autor:
Joseph A. Cacioppo, Po-Ching Patrick Lin, Patrick R. Hannon, Daniel R. McDougle, Arnon Gal, CheMyong Ko
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Ovulation is dependent upon numerous factors mediating follicular growth, vascularization, and ultimately oocyte release via follicle rupture. Endothelin-2 (EDN2) is a potent vasoconstrictor that is transiently produced prior to follicle rup
Externí odkaz:
https://doaj.org/article/c60aa4525a74446b848c5da148aeb77f
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147685 (2016)
Estrogen receptor-α (ESR1) is an important transcriptional regulator in the mammalian oviduct, however ESR1-dependent regulation of the transcriptome of this organ is not well defined, especially at the genomic level. The objective of this study was
Externí odkaz:
https://doaj.org/article/30945f615151406991a30465f18ca70a
Autor:
Arnon Gal, Po-Ching Lin, Joseph A Cacioppo, Patrick R Hannon, Megan M Mahoney, Andrew Wolfe, Rodrigo Fernandez-Valdivia, John P Lydon, Carol F Elias, CheMyong Ko
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159534 (2016)
Ovarian steroids, estradiol and progesterone, play central roles in regulating female reproduction by acting as both positive and negative regulators of gonadotropin-releasing hormone (GnRH) secretion in the hypothalamus. Recent studies have identifi
Externí odkaz:
https://doaj.org/article/f8a17fd0d04946938a2cb1c1767f4ac8
Publikováno v:
Revista Colombiana de Ciencias Pecuarias, Vol 22, Iss 1, Pp 12-18 (2009)
The DNA microarray technology has been widely employed in recent biological research. However, the unprecedented large amount of data produced by the technology has presented inevitable challenges to biological scientists, forcing individual research
Externí odkaz:
https://doaj.org/article/e63051a6918f4c28b457b5382b071451
Autor:
Joseph A Cacioppo, Sang Wook Oh, Hey-young Kim, Jongki Cho, Po-Ching Patrick Lin, Masashi Yanagisawa, CheMyong Ko
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e96115 (2014)
Endothelin-2 (EDN2), a potent vasoconstrictive peptide, is transiently produced by periovulatory follicles at the time of ovulation when corpus luteum (CL) formation begins. EDN2 induces contraction of ovarian smooth muscles ex vivo via an endothelin
Externí odkaz:
https://doaj.org/article/a61972ef9f2a4614aa9bac9288a035b0
Autor:
Eunsook Park, Chin-Hee Song, Jae-Il Park, Ryun-Sup Ahn, Hueng-Sik Choi, CheMyong Ko, Keesook Lee
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104812 (2014)
Transforming growth factor- β1 (TGF-β1) has been reported to inhibit luteinizing hormone (LH) mediated-steroidogenesis in testicular Leydig cells. However, the mechanism by which TGF-β1 controls the steroidogenesis in Leydig cells is not well unde
Externí odkaz:
https://doaj.org/article/f413575824f9414aae7765c9f25d9ef2