Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Che Kang Lim"'
Autor:
Chiaw-Ling Chng, Oi Fah Lai, Lay-Leng Seah, Kai-Ling Yong, Yvonne Hsi-Wei Chung, Rochelle Goh, Che Kang Lim
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
BackgroundThere are no reliable biomarkers to identify Graves’ disease patients who will develop severe Graves’ orbitopathy (GO). We hypothesize that integrating various omics platforms can enhance our understanding of disease mechanisms and unco
Externí odkaz:
https://doaj.org/article/7b2ae8fc00a94e2c82df4cd15c7298cd
Autor:
Nicholas Kim-Wah Yeo, Che Kang Lim, Katherine Nay Yaung, Nicholas Kim Huat Khoo, Thaschawee Arkachaisri, Salvatore Albani, Joo Guan Yeo
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Early-onset systemic lupus erythematosus presents with a more severe disease and is associated with a greater genetic burden, especially in patients from Black, Asian or Hispanic ancestries. Next-generation sequencing techniques, notably whole exome
Externí odkaz:
https://doaj.org/article/d21ed98fec9f4c5290a67e6960831c53
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Immunoglobulin A Deficiency (IgAD) is a polygenic primary immune deficiency, with a strong genetic association to the human leukocyte antigen (HLA) region. Previous genome-wide association studies (GWAS) have identified five non-HLA risk loci (IFIH1,
Externí odkaz:
https://doaj.org/article/9e6417edc18646e18232cd9506a306f8
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 15, Iss 1, Pp 1-8 (2019)
Abstract Background Atypical X-linked severe combined immunodeficiency (X-SCID) is a variant of cellular immunodeficiency due to hypomorphic mutations in the interleukin 2 receptor gamma (IL2RG) gene. Due to a leaky clinical phenotype, diagnosis and
Externí odkaz:
https://doaj.org/article/72288f81d5c04dd8aa2c25b22858adc4
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The pathogenesis in the majority of patients with common variable immunodeficiency (CVID), the most common symptomatic primary immunodeficiency, remains unknown. We aimed to compare the minor and major histocompatibility complex (MHC) markers as well
Externí odkaz:
https://doaj.org/article/28468e87c10042dd974ec0260e251b03
Publikováno v:
Biomarker Insights, Vol 2, Pp 293-298 (2007)
Biomarkers provide certain values for diagnosis, monitor treatment effi cacy, or for the development of novel therapeutic approach for particular diseases. Thus, the identifi cation of specifi c of biomarkers for specifi c medical problems, including
Externí odkaz:
https://doaj.org/article/9c44b91e3f4c42a1a84428ec8b0c396d
Autor:
Kim-Wah Yeo, Nicholas, Che Kang Lim, Nay Yaung, Katherine, Kim Huat Khoo, Nicholas, Thaschawee Arkachaisri, Albani, Salvatore, Joo Guan Yeo
Publikováno v:
Frontiers in Genetics; 2024, p1-15, 15p
Autor:
Cheng Cheng, Che Kang Lim, Mei Po Kwan, Luc Anselin, Min Chen, Wei Luo, Kai Zhang, Carlo Ratti, Guonian Lü, Qiushi Gu, Tao Cheng, Paolo Santi, Michael Batty, Man Sing Wong, Rui Zhu
Publikováno v:
Science Bulletin
Autor:
Chengrong Li, Yu Xia, Lennart Hammarström, Hassan Abolhassani, Yin Luo, Jun Yang, Che Kang Lim, Tingyan He
Publikováno v:
Pediatric Allergy and Immunology. 29:863-872
BACKGROUND Primary immunodeficiency disorders (PID) is a group of heterogeneous diseases mainly characterized by severe and recurrent infections and an increased susceptibility to lymphoproliferative, atopic, and autoimmune conditions. The clinical d
Publikováno v:
Current Neurology and Neuroscience Reports. 19
Recent advancements in next-generation sequencing (NGS) have enabled techniques such as whole exome sequencing (WES) and whole genome sequencing (WGS) to be used to study paroxysmal movement disorders (PMDs). This review summarizes how the recent gen