Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Che J Connon"'
Autor:
Mazyar Yazdani, Aboulghassem Shahdadfar, Sjur Reppe, Dipak Sapkota, Evan M Vallenari, Majlinda Lako, Che J Connon, Francisco C Figueiredo, Tor Paaske Utheim
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243914 (2020)
PurposeSeeking to improve the access to regenerative medicine, this study investigated the structural and transcriptional effects of storage temperature on human oral mucosal epithelial cells (OMECs).MethodsCells were stored at four different tempera
Externí odkaz:
https://doaj.org/article/dd49117b11d344a48c87ad08edd06283
Autor:
Olla Al-Jaibaji, Stephen Swioklo, Kristel Gijbels, Bart Vaes, Francisco C Figueiredo, Che J Connon
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0202118 (2018)
To reduce the increasing need for corneal transplantation, attempts are currently aiming to restore corneal clarity, one potent source of cells are multipotent adult progenitor cells (MAPC®). These cells release a powerful cocktail of paracrine fact
Externí odkaz:
https://doaj.org/article/fdee0fc9204940e2b1cc7f6665a9b2cc
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70860 (2013)
Limbal epithelial stem cells may ameliorate limbal stem cell deficiency through secretion of therapeutic proteins, delivered to the cornea in a controlled manner using hydrogels. In the present study the secretome of alginate-encapsulated limbal epit
Externí odkaz:
https://doaj.org/article/6cfcc408b86c4ebea244037a4271b2bc
Autor:
Che J Connon, Takahiro Nakamura, Andy Hopkinson, Andrew Quantock, Naoto Yagi, James Doutch, Keith M Meek
Publikováno v:
PLoS ONE, Vol 2, Iss 11, p e1147 (2007)
Pre-term birth is the leading cause of perinatal and neonatal mortality, 40% of which are attributed to the pre-term premature rupture of amnion. Rupture of amnion is thought to be associated with a corresponding decrease in the extracellular collage
Externí odkaz:
https://doaj.org/article/892b27d1ca5d4c1eb6521ee27806fd60
Publikováno v:
Bioengineering, Vol 10, Iss 1, p 23 (2022)
Over the last decade, progress in three dimensional (3D) bioprinting has advanced considerably. The ability to fabricate complex 3D structures containing live cells for drug discovery and tissue engineering has huge potential. To realise successful c
Externí odkaz:
https://doaj.org/article/89bd0e9753464a26b633baa423dd4f03
Publikováno v:
Frontiers in Mechanical Engineering. 8
The principle of three-dimensional (3D) bio-printing involves integration of biomaterials, live cells and controlled motor systems for creating complex biomimetic constructs. Bio-ink is one of the most important components in the process of 3D bio-pr
Autor:
Ricardo M. Gouveia, Che J. Connon
Publikováno v:
ACS applied bio materials. 2(2)
In this study, we used tissue templating technology to direct human dermal fibroblasts to biofabricate large-area tissues that closely emulate the natural dermis. This technology also allowed the new tissues to promote their own release from the temp
Autor:
Ricardo M. Gouveia, Guillaume Lepert, Suneel Gupta, Rajiv R. Mohan, Carl Paterson, Che J. Connon
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
The link between how the stiffness of the cornea affects stem cells is unclear. Here, the authors use Brillouin spectro-microscopy to show that mechanical properties of the cornea affect epithelial stem cells and after injury, treating the cornea wit
Publikováno v:
Biomedical materials (Bristol, England). 17(2)
Corneal blindness is the major cause of vision impairment and the fourth-largest leading cause of blindness worldwide. An allograft corneal transplant is the most routine treatment for visual loss. Further complications can occur, such as transplant
Autor:
Sanja Bojic, Gary Reynolds, Sunanda Dey, Saurabh Ghosh, Muzlifah Haniffa, Lyle Armstrong, Lucy Clarke, Jonathan Coxhead, Birthe Dorgau, Rachel Queen, Rafiqul Hussain, Chunbo Yang, Marina Moya Molina, Francisco C Figueiredo, Paul Rooney, Majlinda Lako, Nicky Moyse, Che J. Connon, Deborah J. Henderson, Darin Zerti, Joseph Collin, Agatha Joseph, Steven Lisgo
Publikováno v:
The Ocular Surface
Purpose Single cell (sc) analyses of key embryonic, fetal and adult stages were performed to generate a comprehensive single cell atlas of all the corneal and adjacent conjunctival cell types from development to adulthood. Methods Four human adult an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7c1670da539307d991067a269111fea
http://hdl.handle.net/11697/170345
http://hdl.handle.net/11697/170345