Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Che Chung Tsai"'
Autor:
Lisa M Frenkel, LaRene Kuller, Ingrid A Beck, Che-Chung Tsai, Jaimy P Joy, Thera M Mulvania, Shiu-Lok Hu, David C Montefiori, David M Anderson
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0240495 (2021)
Rationale/study designA major challenge in the development of HIV vaccines is finding immunogens that elicit protection against a broad range of viral strains. Immunity to a narrow range of viral strains may protect infants of HIV-infected women or p
Externí odkaz:
https://doaj.org/article/99f0f2faa8574d5383e9787051ec8303
Autor:
A Gregory Bruce, Helle Bielefeldt-Ohmann, Serge Barcy, Angela M Bakke, Patrick Lewis, Che-Chung Tsai, Robert D Murnane, Timothy M Rose
Publikováno v:
PLoS Pathogens, Vol 8, Iss 10, p e1002962 (2012)
Two gammaherpesviruses, Epstein-Barr virus (EBV) (Lymphocryptovirus genus) and Kaposi's sarcoma-associated herpesvirus (KSHV) (Rhadinovirus genus) have been implicated in the etiology of AIDS-associated lymphomas. Homologs of these viruses have been
Externí odkaz:
https://doaj.org/article/62173432837e4900b83ec405e342b182
Autor:
Jaimy P Joy, David M. Anderson, Thera M. Mulvania, LaRene Kuller, Che-Chung Tsai, Lisa M. Frenkel, Ingrid A. Beck, David C. Montefiori, Shiu Lok Hu
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 4, p e0240495 (2021)
PLoS ONE, Vol 16, Iss 4, p e0240495 (2021)
Rationale/Study design A major challenge in the development of HIV vaccines is finding immunogens that elicit protection against a broad range of viral strains. Immunity to a narrow range of viral strains may protect infants of HIV-infected women or
Autor:
Che-Chung Tsai1 cctsai@bart.rprc.washington.edu, Emau, Peter1, Sun, Joseph C.1, Beck, Thomas W.1, Tran, Chy-Anh1, Follis, Kathryn E.1, Bischofberger, Norbert2, Morton, William R.1
Publikováno v:
Journal of Medical Primatology. Aug2000, Vol. 29 Issue 3/4, p248-258. 11p.
Autor:
Sung Up Choi, Dale Whittington, Bradley D. Anderson, Jashvant D. Unadkat, Loren Kinman, Amal Kaddoumi, Rodney J. Y. Ho, Che Chung Tsai
Publikováno v:
Drug Metabolism and Disposition. 35:1459-1462
P-glycoprotein (P-gp) expression at the rodent blood-brain barrier (BBB) limits the central nervous system (CNS) distribution of anti-human immunodeficiency virus (HIV) protease inhibitors (PIs). However, it is not clear whether P-gp activity at the
Publikováno v:
Cellular Microbiology
Novel therapeutic approaches are needed to combat the rapid increase in HIV sexual transmission in women. The probiotic organism Lactobacillus reuteri RC-14 which safely colonizes the human vagina and prevents microbial infections, has been genetical
Publikováno v:
Journal of Medical Primatology. 33:105-108
Preclinical studies of topical microbicide products, using appropriate animal models for assessing the safety of repeated use are essential. The pig-tailed macaque (Macaca nemestrina) model has been used to assess the safety of vaginally and rectally
Autor:
Ann Schmidt, Che Chung Tsai, Michael B. Agy, William R. Morton, Peter Emau, Robin J. Shattock, Kirk R. Gustafson, Michael R. Boyd, Yonghou Jiang
Publikováno v:
AIDS Research and Human Retroviruses. 20:11-18
The cyanobacterial protein cyanovirin-N (CV-N) potently inactivates diverse strains of HIV-1 and other lentiviruses due to irreversible binding of CV-N to the viral envelope glycoprotein gp120. In this study, we show that recombinant CV-N effectively
Autor:
Joseph C. Sun, Peter Emau, William R. Morton, Norbert Bischofberger, Kathryn E. Follis, Thomas W. Beck, Chy-Anh Tran, Che-Chung Tsai
Publikováno v:
Journal of Medical Primatology. 29:248-258
We report that simian immunodeficiency virus (SIV) infection in macaques is a valuable animal model for studying post-exposure chemoprophylaxis (PECP). PECP with the acyclic nucleoside reverse transcriptase inhibitors 9-(2-phosphonylmetho-xyethyl)ade
Autor:
William R. Morton, Jeannette Bannink, Ann Schmidt, David M. Anderson, Janela McClure, Che Chung Tsai, Marie Anne Rey-Cuille, Lynda Misher, Shiu Lok Hu
Publikováno v:
Journal of Medical Primatology. 29:114-126
With few exceptions, humans are the only species known to develop acquired immunodeficiency syndrome (AIDS) after human immunodeficiency virus (HIV) infection. We report here that an isolate of HIV type 2, EHO, readily established persistent infectio