Preferential and persistent impact of acute HIV-1 infection on CD4+iNKT cells in colonic mucosa

Autor: Kerri G. Lal, Rungsun Rerknimitr, Leigh Anne Eller, Aljawharah Alrubayyi, Dominic Paquin-Proulx, Eugene Kroon, Shelly J. Krebs, Andrey Tokarev, Diane L. Bolton, Suchada Suhkumvittaya, Suteeraporn Pinyakorn, Nelson L. Michael, Merlin L. Robb, Bonnie M. Slike, Johan K. Sandberg, Mark de Souza, Matthew Creegan, Alexandra Schuetz, Nicolas Chomont, Nittaya Phanuphak, Nitiya Chomchey, Yuwadee Phuang-Ngern, Michael A. Eller, Jintanat Ananworanich, study groups, Chayada Sajjaweerawan, Amélie Pagliuzza

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 118(46):e2104721118. National Academy of Sciences

Acute HIV-1 infection (AHI) results in the widespread depletion of CD4+ T cells in peripheral blood and gut mucosal tissue. However, the impact on the predominantly CD4+ immunoregulatory invariant natural killer T (iNKT) cells during AHI remains unkn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e229f3fff588719c48064e2160b7cc97
https://doi.org/10.1073/pnas.2104721118