Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Chawita, Netirojjanakul"'
Autor:
Shu-Chen Lu, Michelle Chen, Larissa Atangan, Elizabeth A. Killion, Renee Komorowski, Yuan Cheng, Chawita Netirojjanakul, James R. Falsey, Marina Stolina, Denise Dwyer, Clarence Hale, Shanaka Stanislaus, Todd Hager, Veena A. Thomas, John M. Harrold, David J. Lloyd, Murielle M. Véniant
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 5, Pp 100263- (2021)
Summary: Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) regulate glucose and energy homeostasis. Targeting both pathways with GIP receptor (GIPR) antagonist antibody (GIPR-Ab) and GLP-1 receptor (GLP-1R) agonis
Externí odkaz:
https://doaj.org/article/6fa1243f07684a9b91237d0446fb0986
Autor:
Iain D. G. Campuzano, Emma M. Pelegri-O’Day, Nithya Srinivasan, Jennifer L. Lippens, Pascal Egea, Aiko Umeda, Jennifer Aral, Tianqi Zhang, Arthur Laganowsky, Chawita Netirojjanakul
Publikováno v:
Journal of the American Society for Mass Spectrometry. 33(11)
Reversed-phase liquid chromatographic mass spectrometry (rpLC-MS) is a universal, platformed, and essential analytical technique within pharmaceutical and biopharmaceutical research. Typical rpLC method gradient times can range from 5 to 20 min. As m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2ef181e1f10aa073828eb56f4487665
https://pubmed.ncbi.nlm.nih.gov/36206542
https://pubmed.ncbi.nlm.nih.gov/36206542
Autor:
Jeremy J. Wolff, Joseph A. Loo, Piriya Wongkongkathep, Iain Campuzano, Huilin Li, Michael Nshanian, Chawita Netirojjanakul, Carter Lantz, Chris Spahr
Publikováno v:
J Am Soc Mass Spectrom
Journal of the American Society for Mass Spectrometry, vol 31, iss 5
Journal of the American Society for Mass Spectrometry, vol 31, iss 5
Analysis of proteins and complexes under native mass spectrometric (MS) and solution conditions was typically performed using the time-of-flight analyzers, due to their routine high m/z transmission and detection capabilities. However, over recent ye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87e9e889b3f169a9dc6221a849864816
https://doi.org/10.1021/jasms.0c00030
https://doi.org/10.1021/jasms.0c00030
Autor:
Brad Herberich, Thomas Nixey, Lin Yin, Tayo Ikotun, Kelvin K. C. Sham, Jason Long, Hongyan Li, Charles Glaus, Xuhai Be, Les P. Miranda, Yuan Cheng, Marcus Soto, James R. Falsey, Bryan D. Moyer, Robert S. Foti, Christopher M. Tegley, Chawita Netirojjanakul, Linh Tran, Kip P. Conner, Jennifer Aral, Liyue Huang, Kaustav Biswas, Justin K. Murray, Bin Wu, Loren Berry, Dean Hickman, Dan A. Rock
Publikováno v:
Drug Metabolism and Disposition. 47:1111-1121
The identification of nonopioid alternatives to treat chronic pain has received a great deal of interest in recent years. Recently, the engineering of a series of Nav1.7 inhibitory peptide-antibody conjugates has been reported, and herein, the precli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aafa704103c2cd45fe6f198cffc5d5f
https://doi.org/10.1124/dmd.119.087742
https://doi.org/10.1124/dmd.119.087742
Autor:
John O. Hui, Stone D.-H. Shi, Pascal F. Egea, John H. Robinson, Jennifer L. Lippens, Michael Nshanian, Dhanashri Bagal, Joseph A. Loo, Marshall Bern, Chawita Netirojjanakul, Iain D. G. Campuzano
Publikováno v:
Analytical chemistry, vol 91, iss 15
Anal Chem
Anal Chem
Electrospray ionization mass spectrometry (ESI-MS) is a ubiquitously used analytical method applied across multiple departments in biopharma, ranging from early research discovery to process development. Accurate, efficient, and consistent protein MS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f7aaae0becae8f11e2aee4a6b6824f5
https://doi.org/10.1021/acs.analchem.9b00062
https://doi.org/10.1021/acs.analchem.9b00062
Autor:
Bryan D. Moyer, Brad Herberich, Kaustav Biswas, Kenneth W. Walker, Beth D. Youngblood, Jennifer Aral, Tayo Ikotun, Min-Hwa Jasmine Lin, Linh Tran, Thomas Kornecook, Hongyan Li, Thomas Nixey, Joseph Ligutti, Shanti Amagasu, Li Yin, Xuhai Be, Kristin L. Andrews, Christopher M. Tegley, Charles Glaus, Marcus Soto, Les P. Miranda, James R. Falsey, Jason Long, Yuan Cheng, Robert S. Foti, Hossein Salimi-Moosavi, Kelvin Sham, Christopher P Ilch, Bin Wu, Justin K. Murray, Margaret Karow, Chawita Netirojjanakul, Liz Doherty
Publikováno v:
ACS Chemical Biology. 14:806-818
Drug discovery research on new pain targets with human genetic validation, including the voltage-gated sodium channel NaV1.7, is being pursued to address the unmet medical need with respect to chronic pain and the rising opioid epidemic. As part of e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68d1aa4016111a37796e962e98dcd944
https://doi.org/10.1021/acschembio.9b00183
https://doi.org/10.1021/acschembio.9b00183
Autor:
Elizabeth A. Killion, Yuan Cheng, John M. Harrold, Veena A. Thomas, Shu-Chen Lu, James R. Falsey, Chawita Netirojjanakul, David Lloyd, Clarence Hale, Todd Hager, Shanaka Stanislaus, Marina Stolina, Renee Komorowski, Larissa Atangan, Murielle M. Véniant, Denise Dwyer, Michelle Chen
Publikováno v:
Cell Reports Medicine
Cell Reports Medicine, Vol 2, Iss 5, Pp 100263-(2021)
Cell Reports Medicine, Vol 2, Iss 5, Pp 100263-(2021)
Summary Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) regulate glucose and energy homeostasis. Targeting both pathways with GIP receptor (GIPR) antagonist antibody (GIPR-Ab) and GLP-1 receptor (GLP-1R) agonist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38ac5166f5323cefa07e391f43ee52d4
https://pubmed.ncbi.nlm.nih.gov/34095885
https://pubmed.ncbi.nlm.nih.gov/34095885
Autor:
Steven L. Van Orden, Iain Campuzano, Joseph A. Loo, Jennifer L. Lippens, Michael Nshanian, Chawita Netirojjanakul, David P. A. Kilgour
Publikováno v:
Analytical Chemistry. 90:745-751
Antibody drug conjugates (ADCs) are an important class of therapeutic molecule currently being used to treat HER2-positive metastatic breast cancer, relapsed or refractory Hodgkin lymphoma, systemic anaplastic large cell lymphoma, relapsed or refract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0021c5f9e4b3ea2b483eda4b2cdc88b1
https://doi.org/10.1021/acs.analchem.7b03021
https://doi.org/10.1021/acs.analchem.7b03021
Autor:
Justin K, Murray, Bin, Wu, Christopher M, Tegley, Thomas E, Nixey, James R, Falsey, Brad, Herberich, Li, Yin, Kelvin, Sham, Jason, Long, Jennifer, Aral, Yuan, Cheng, Chawita, Netirojjanakul, Liz, Doherty, Charles, Glaus, Tayo, Ikotun, Hongyan, Li, Linh, Tran, Marcus, Soto, Hossein, Salimi-Moosavi, Joseph, Ligutti, Shanti, Amagasu, Kristin L, Andrews, Xuhai, Be, Min-Hwa Jasmine, Lin, Robert S, Foti, Christopher P, Ilch, Beth, Youngblood, Thomas J, Kornecook, Margaret, Karow, Kenneth W, Walker, Bryan D, Moyer, Kaustav, Biswas, Les P, Miranda
Publikováno v:
ACS chemical biology. 14(4)
Drug discovery research on new pain targets with human genetic validation, including the voltage-gated sodium channel Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a795b15b8b6e13088e7422d887dacec6
https://pubmed.ncbi.nlm.nih.gov/30875193
https://pubmed.ncbi.nlm.nih.gov/30875193
Autor:
Iain D. G. Campuzano, Mai B. Thayer, Brooke M. Rock, Sara C. Humphreys, Chawita Netirojjanakul
Publikováno v:
Nucleic acid therapeutics. 29(3)
The potential repertoire of short interfering RNA (siRNA) therapeutics is expanding as targeting strategies evolve. One approach to enable organ-specific delivery has been to directly conjugate siRNA to a monoclonal antibody (siRNA-mAb), analogous to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad36f389d014e58e54b42a4c59040070
https://pubmed.ncbi.nlm.nih.gov/30801231
https://pubmed.ncbi.nlm.nih.gov/30801231