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Supramolecular Cylinders Target Bulge Structures in the 5' UTR of the RNA Genome of SARS-CoV-2 and Inhibit Viral Replication.

Autor: Melidis L; Physical Sciences for Health Centre University of Birmingham Edgbaston Birmingham B15 2TT UK., Hill HJ; Institute of Immunology and Immunotherapy University of Birmingham Edgbaston Birmingham B15 2TT UK., Coltman NJ; School of Biosciences University of Birmingham Edgbaston Birmingham B15 2TT UK., Davies SP; Institute of Immunology and Immunotherapy University of Birmingham Edgbaston Birmingham B15 2TT UK., Winczura K; School of Biosciences University of Birmingham Edgbaston Birmingham B15 2TT UK., Chauhan T; Physical Sciences for Health Centre University of Birmingham Edgbaston Birmingham B15 2TT UK., Craig JS; Physical Sciences for Health Centre University of Birmingham Edgbaston Birmingham B15 2TT UK., Garai A; School of Chemistry University of Birmingham Edgbaston Birmingham B15 2TT UK., Hooper CAJ; School of Chemistry University of Birmingham Edgbaston Birmingham B15 2TT UK., Egan RT; School of Chemistry University of Birmingham Edgbaston Birmingham B15 2TT UK., McKeating JA; Nuffield Department of Medicine & Chinese Academy of Medical Sciences (CAMS) Oxford Institute (COI) Oxford University Oxford OX3 7BN UK., Hodges NJ; School of Biosciences University of Birmingham Edgbaston Birmingham B15 2TT UK., Stamataki Z; Institute of Immunology and Immunotherapy University of Birmingham Edgbaston Birmingham B15 2TT UK., Grzechnik P; School of Biosciences University of Birmingham Edgbaston Birmingham B15 2TT UK., Hannon MJ; Physical Sciences for Health Centre University of Birmingham Edgbaston Birmingham B15 2TT UK.; School of Chemistry University of Birmingham Edgbaston Birmingham B15 2TT UK.

Publikováno v: Angewandte Chemie (Weinheim an der Bergstrasse, Germany) [Angew Chem Weinheim Bergstr Ger] 2021 Aug 09; Vol. 133 (33), pp. 18292-18299. Date of Electronic Publication: 2021 Jul 09.