Interferon restores replication fork stability and cell viability in BRCA-defective cells via ISG15.

Autor: Moro RN; University of Zurich, Institute of Molecular Cancer Research, 8057, Zurich, Switzerland., Biswas U; University of Zurich, Institute of Molecular Cancer Research, 8057, Zurich, Switzerland., Kharat SS; Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, 21702, MD, USA., Duzanic FD; University of Zurich, Institute of Molecular Cancer Research, 8057, Zurich, Switzerland., Das P; Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015GD, Rotterdam, the Netherlands., Stavrou M; University of Zurich, Institute of Molecular Cancer Research, 8057, Zurich, Switzerland., Raso MC; University of Zurich, Institute of Molecular Cancer Research, 8057, Zurich, Switzerland., Freire R; Fundación Canaria del Instituto de Investigación Sanitaria de Canarias (FIISC), Unidad de Investigación, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Spain.; Instituto de Tecnologías Biomédicas, Universidad de La Laguna, 38200, La Laguna, Spain.; Universidad Fernando Pessoa Canarias, Las Palmas de Gran Canaria, Spain., Chaudhuri AR; Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015GD, Rotterdam, the Netherlands., Sharan SK; Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, 21702, MD, USA., Penengo L; University of Zurich, Institute of Molecular Cancer Research, 8057, Zurich, Switzerland. penengo@imcr.uzh.ch.

Publikováno v: Nature communications [Nat Commun] 2023 Oct 02; Vol. 14 (1), pp. 6140. Date of Electronic Publication: 2023 Oct 02.

β-hydroxybutyrate is a metabolic regulator of proteostasis in the aged and Alzheimer disease brain.

Autor: Madhavan SS; Buck Institute for Research on Aging, Novato, CA, USA.; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.; Department of Geriatrics, University of California San Francisco, San Francisco, CA, USA., Roa Diaz S; Buck Institute for Research on Aging, Novato, CA, USA.; Department of Geriatrics, University of California San Francisco, San Francisco, CA, USA., Peralta S; Buck Institute for Research on Aging, Novato, CA, USA., Nomura M; Buck Institute for Research on Aging, Novato, CA, USA., King CD; Buck Institute for Research on Aging, Novato, CA, USA., Lin A; Buck Institute for Research on Aging, Novato, CA, USA., Bhaumik D; Buck Institute for Research on Aging, Novato, CA, USA., Shah S; Buck Institute for Research on Aging, Novato, CA, USA., Blade T; Buck Institute for Research on Aging, Novato, CA, USA., Gray W; Buck Institute for Research on Aging, Novato, CA, USA., Chamoli M; Buck Institute for Research on Aging, Novato, CA, USA., Eap B; Buck Institute for Research on Aging, Novato, CA, USA.; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Panda O; Buck Institute for Research on Aging, Novato, CA, USA., Diaz D; Buck Institute for Research on Aging, Novato, CA, USA., Garcia TY; Buck Institute for Research on Aging, Novato, CA, USA.; Department of Geriatrics, University of California San Francisco, San Francisco, CA, USA., Stubbs BJ; Buck Institute for Research on Aging, Novato, CA, USA., Lithgow GJ; Buck Institute for Research on Aging, Novato, CA, USA.; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Schilling B; Buck Institute for Research on Aging, Novato, CA, USA.; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Verdin E; Buck Institute for Research on Aging, Novato, CA, USA.; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Chaudhuri AR; Buck Institute for Research on Aging, Novato, CA, USA., Newman JC; Buck Institute for Research on Aging, Novato, CA, USA.; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.; Department of Geriatrics, University of California San Francisco, San Francisco, CA, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Jul 03. Date of Electronic Publication: 2023 Jul 03.

SMARCAD1-mediated active replication fork stability maintains genome integrity.

Autor: Lo CSY; Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3000 CA Rotterdam, Netherlands., van Toorn M; Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3000 CA Rotterdam, Netherlands.; Oncode Institute, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3000 CA Rotterdam, Netherlands., Gaggioli V; Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3000 CA Rotterdam, Netherlands., Paes Dias M; Division of Molecular Pathology, Oncode Institute, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, Netherlands., Zhu Y; Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3000 CA Rotterdam, Netherlands., Manolika EM; Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3000 CA Rotterdam, Netherlands., Zhao W; Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3000 CA Rotterdam, Netherlands., van der Does M; Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3000 CA Rotterdam, Netherlands., Mukherjee C; Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3000 CA Rotterdam, Netherlands., G S C Souto Gonçalves J; Division of Radiation and Genome Stability, Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA., van Royen ME; Department of Pathology, Cancer Treatment Screening Facility (CTSF), Erasmus Optical Imaging Centre (OIC), Erasmus University Medical Center, Wytemaweg 80, 3015 CN Rotterdam, Netherlands., French PJ; Department of Neurology and Cancer Treatment Screening Facility (CTSF), Erasmus University Medical Center, Erasmus MC Cancer Institute, Rotterdam, Netherlands., Demmers J; Proteomics Center and Department of Biochemistry, Erasmus University Medical Center, Wytemaweg 80, 3015 CN Rotterdam, Netherlands., Smal I; Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3000 CA Rotterdam, Netherlands., Lans H; Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3000 CA Rotterdam, Netherlands., Wheeler D; Laboratory of Biochemistry and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA., Jonkers J; Division of Molecular Pathology, Oncode Institute, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, Netherlands., Chaudhuri AR; Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3000 CA Rotterdam, Netherlands., Marteijn JA; Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3000 CA Rotterdam, Netherlands.; Oncode Institute, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3000 CA Rotterdam, Netherlands., Taneja N; Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3000 CA Rotterdam, Netherlands. n.taneja@erasmusmc.nl.

Publikováno v: Science advances [Sci Adv] 2021 May 05; Vol. 7 (19). Date of Electronic Publication: 2021 May 05 (Print Publication: 2021).

Superior optical (λ ∼ 1550 nm) emission and detection characteristics of Ge microdisks grown on virtual Si 0.5 Ge 0.5 /Si substrates using molecular beam epitaxy.

Autor: Singh S; Department of Physics, Indian Institute of Technology, Kharagpur-721302 Kharagpur, India., Katiyar AK, Sarkar A, Shihabudeen PK, Chaudhuri AR, Goswami DK, Ray SK

Publikováno v: Nanotechnology [Nanotechnology] 2020 Mar 13; Vol. 31 (11), pp. 115206. Date of Electronic Publication: 2019 Nov 22.

Ethyl N-(5-bromo-3-phenylindol-2-yl)carbamate

Autor: Mruthyunjayaswamy, BHM, Ijare, OB, Jadegoud, Y, Chaudhuri, AR, Row, TNG

The crystal structure of the title compound, C17H15BrN2O2, has been determined at room temperature. The indole moiety is essentially planar and the structure is stabilized by intra- and intermolecular N-H...O hydrogen bonds.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______182::51d0178834bfc5e68f1a940b3d1fefb1
http://eprints.iisc.ernet.in/18372/