Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Chau My-Ta"'
Autor:
Susheel K. Gunasekar, Litao Xie, Ashutosh Kumar, Juan Hong, Pratik R. Chheda, Chen Kang, David M. Kern, Chau My-Ta, Joshua Maurer, John Heebink, Eva E. Gerber, Wojciech J. Grzesik, Macaulay Elliot-Hudson, Yanhui Zhang, Phillip Key, Chaitanya A. Kulkarni, Joseph W. Beals, Gordon I. Smith, Isaac Samuel, Jessica K. Smith, Peter Nau, Yumi Imai, Ryan D. Sheldon, Eric B. Taylor, Daniel J. Lerner, Andrew W. Norris, Samuel Klein, Stephen G. Brohawn, Robert Kerns, Rajan Sah
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-25 (2022)
Type 2 diabetes is associated with insulin resistance, impaired insulin secretion and liver steatosis. Here the authors report a proof-of-concept study for small molecule SWELL1 modulators as a therapeutic approach to treat diabetes and associated li
Externí odkaz:
https://doaj.org/article/f4d1fee19c624c0a9f1b40ef56f78e04
Autor:
Ahmad F Alghanem, Javier Abello, Joshua M Maurer, Ashutosh Kumar, Chau My Ta, Susheel K Gunasekar, Urooj Fatima, Chen Kang, Litao Xie, Oluwaseun Adeola, Megan Riker, Macaulay Elliot-Hudson, Rachel A Minerath, Chad E Grueter, Robert F Mullins, Amber N Stratman, Rajan Sah
Publikováno v:
eLife, Vol 10 (2021)
The endothelium responds to numerous chemical and mechanical factors in regulating vascular tone, blood pressure, and blood flow. The endothelial volume-regulated anion channel (VRAC) has been proposed to be mechanosensitive and thereby sense fluid f
Externí odkaz:
https://doaj.org/article/078560485a37441a90c596b50ccc3063
Autor:
Ashutosh Kumar, Litao Xie, Chau My Ta, Antentor O Hinton, Susheel K Gunasekar, Rachel A Minerath, Karen Shen, Joshua M Maurer, Chad E Grueter, E Dale Abel, Gretchen Meyer, Rajan Sah
Publikováno v:
eLife, Vol 9 (2020)
Maintenance of skeletal muscle is beneficial in obesity and Type 2 diabetes. Mechanical stimulation can regulate skeletal muscle differentiation, growth and metabolism; however, the molecular mechanosensor remains unknown. Here, we show that SWELL1 (
Externí odkaz:
https://doaj.org/article/7f3ff750fcd64addb27a683c2c1e631a
Autor:
Rachel A Minerath, Megan J Riker, Chau My Ta, Robert F. Mullins, Rajan Sah, Joshua M Maurer, Ashutosh Kumar, Amber N. Stratman, Macaulay Elliot-Hudson, Susheel K. Gunasekar, Oluwaseun Adeola, Chad E. Grueter, Ahmad F. Alghanem, Urooj Fatima, Javier Abello, Chen Kang, Litao Xie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::deb3a6f4ba01b3e9b15ee8dff69a7c3c
https://doi.org/10.7554/elife.61313.sa2
https://doi.org/10.7554/elife.61313.sa2
Autor:
E. Dale Abel, Chau My Ta, Rajan Sah, Rachel A Minerath, Joshua M Maurer, Ashutosh Kumar, Chad E. Grueter, Gretchen A. Meyer, Susheel K. Gunasekar, Antentor Othrell Hinton, Litao Xie, Karen Shen
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Maintenance of skeletal muscle is beneficial in obesity and Type 2 diabetes. Mechanical stimulation can regulate skeletal muscle differentiation, growth and metabolism; however, the molecular mechanosensor remains unknown. Here, we show that SWELL1 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f6d75331556a8ab0aab3ba540f2989
https://elifesciences.org/articles/58941
https://elifesciences.org/articles/58941
Autor:
E. Dale Abel, Litao Xie, Rajan Sah, Gretchen A. Meyer, Rachel A Minerath, Karen Shen, Antentor Othrell Hinton, Joshua M Maurer, Chau My Ta, Susheel K. Gunasekar, Ashutosh Kumar, Chad E. Grueter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a244d9076ad3c4d26f4f3144c64191bb
https://doi.org/10.7554/elife.58941.sa2
https://doi.org/10.7554/elife.58941.sa2
Autor:
Rajan Sah, Antentor J. Hinton, E. Dale Abel, Gretchen A. Meyer, Litao Xie, Rachel A Minerath, Joshua M Maurer, Susheel K. Gunasekar, Karen Shen, Chad E. Grueter, Chau My Ta, Ashutosh Kumar
Maintenance of skeletal muscle is beneficial in obesity and Type 2 diabetes. Mechanical stimulation can regulate skeletal muscle differentiation, growth and metabolism, however the molecular mechanosensor remains unknown. Here, we show that SWELL1 (L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7ef4dbee6fa741c4001cd7f32d62ad2
https://doi.org/10.1101/2020.06.04.134213
https://doi.org/10.1101/2020.06.04.134213
Publikováno v:
Cell Signal
Variants in genes which encode for polycystin-1 and polycystin-2 cause most forms of autosomal dominant polycystic disease (ADPKD). Despite our strong understanding of the genetic determinants of ADPKD, we do not understand the structural features wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c7054a6544c1449e713bb2f1d95777
https://doi.org/10.1016/j.cellsig.2020.109626
https://doi.org/10.1016/j.cellsig.2020.109626
Autor:
Alghanem, Ahmad F., Abello, Javier, Maurer, Joshua M., Kumar, Ashutosh, Chau My Ta, Gunasekar, Susheel K., Fatima, Urooj, Chen Kang, Litao Xie, Adeola, Oluwaseun, Riker, Megan, Elliot-Hudson, Macaulay, Minerath, Rachel A., Grueter, Chad E., Mullins, Robert F., Stratman, Amber N., Sah, Rajan
Publikováno v:
eLife; 3/19/2021, p1-29, 29p
Autor:
Kumar, Ashutosh, Litao Xie, Chau My Ta, Hinton, Antentor O., Gunasekar, Susheel K., Minerath, Rachel A., Shen, Karen, Maurer, Joshua M., Grueter, Chad E., Abel, E. Dale, Meyer, Gretchen, Sah, Rajan
Publikováno v:
eLife; 10/7/2020, p1-27, 27p