Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Chase Kingsbury"'
Autor:
Jea-Young Lee, Zhen-Jie Wang, Alexa Moscatello, Chase Kingsbury, Blaise Cozene, Jeffrey Farooq, Madeline Saft, Nadia Sadanandan, Bella Gonzales-Portillo, Henry Zhang, Felipe Esparza Salazar, Alma Rosa Lezama Toledo, Germán Rivera Monroy, Reed Berlet, Cyndy D. Sanberg, Paul R. Sanberg, Cesario V. Borlongan
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-10 (2022)
Gut-Brain Axis as a PD Pathologic Source and Therapeutic Target. The PD murine model of α-synuclein overexpression at around 8 weeks of age manifests gut dysbiosis, characterized by inflammation-specific microbiota and cytokines, which can trigger b
Externí odkaz:
https://doaj.org/article/d730f1393411479c90a69d8a58f04dc4
Autor:
Chase Kingsbury, Liborio Stuppia
Publikováno v:
Brain Circulation, Vol 7, Iss 1, Pp 18-22 (2021)
Human amniotic fluid stem cells (hAFSCs) are growing in interest; yet, little is understood about their secretome and neuroprotective actions in different diseases, including stroke. When stem cells are grown in vitro, they release an array of cytoki
Externí odkaz:
https://doaj.org/article/fb430215b4db4a839aa143c55243b69c
Autor:
Yuji Kaneko, Jea‐Young Lee, Naoki Tajiri, Julian P. Tuazon, Trenton Lippert, Eleonora Russo, Seong‐Jin Yu, Brooke Bonsack, Sydney Corey, Alexandreya B. Coats, Chase Kingsbury, Thomas N. Chase, Minako Koga, Cesar V. Borlongan
Publikováno v:
Stem Cells Translational Medicine, Vol 9, Iss 2, Pp 203-220 (2020)
Abstract The present study used in vitro and in vivo stroke models to demonstrate the safety, efficacy, and mechanism of action of adult human bone marrow‐derived NCS‐01 cells. Coculture with NCS‐01 cells protected primary rat cortical cells or
Externí odkaz:
https://doaj.org/article/fde3b4a51a0044ce98994e0e757c6a16
Autor:
Brooke Bonsack, Matt Heyck, Chase Kingsbury, Blaise Cozene, Nadia Sadanandan, Jea-Young Lee, Cesar V Borlongan
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 7, Pp 1179-1190 (2020)
Traumatic brain injury remains a global health crisis that spans all demographics, yet there exist limited treatment options that may effectively curtail its lingering symptoms. Traumatic brain injury pathology entails a progression from primary inju
Externí odkaz:
https://doaj.org/article/3b0781378e884a1d83cade6c00ccfe2c
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 6, Pp 1014-1018 (2020)
Stroke persists as a global health and economic crisis, yet only two interventions to reduce stroke-induced brain injury exist. In the clinic, many patients who experience an ischemic stroke often further suffer from retinal ischemia, which can inhib
Externí odkaz:
https://doaj.org/article/334d67e62a4349bebbccbdc58deac9e9
Autor:
Nadia Sadanandan, Alex Shear, Beverly Brooks, Madeline Saft, Dorothy Anne Galang Cabantan, Chase Kingsbury, Henry Zhang, Stefan Anthony, Zhen-Jie Wang, Felipe Esparza Salazar, Alma R. Lezama Toledo, Germán Rivera Monroy, Joaquin Vega Gonzales-Portillo, Alexa Moscatello, Jea-Young Lee, Cesario V. Borlongan
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Stem cell therapy may present an effective treatment for metastatic brain cancer and glioblastoma. Here we posit the critical role of a leaky blood-brain barrier (BBB) as a key element for the development of brain metastases, specifically melanoma. B
Externí odkaz:
https://doaj.org/article/39cba048fef04af98ebce458c103aff1
Autor:
Blaise Cozene, Nadia Sadanandan, Jeffrey Farooq, Chase Kingsbury, You Jeong Park, Zhen-Jie Wang, Alexa Moscatello, Madeline Saft, Justin Cho, Bella Gonzales-Portillo, Cesar V Borlongan
Publikováno v:
Cell Transplantation, Vol 30 (2021)
Traumatic brain injury (TBI) is a pervasive and damaging form of acquired brain injury (ABI). Acute, subacute, and chronic cell death processes, as a result of TBI, contribute to the disease progression and exacerbate outcomes. Extended neuroinflamma
Externí odkaz:
https://doaj.org/article/c5209b97278a43248781c07e86629ba7
Autor:
Hung Nguyen, Sydney Zarriello, Alexandreya Coats, Cannon Nelson, Chase Kingsbury, Anna Gorsky, Mira Rajani, Elliot G. Neal, Cesar V. Borlongan
Publikováno v:
Neurobiology of Disease, Vol 126, Iss , Pp 85-104 (2019)
Age-related neurological disorders continue to pose a significant societal and economic burden. Aging is a complex phenomenon that affects many aspects of the human body. Specifically, aging can have detrimental effects on the progression of brain di
Externí odkaz:
https://doaj.org/article/47ee72f3bba342449d0ca00ca2a86397
Autor:
Yuyang Zhang, Seongjin Yu, Julian P Tuazon, Jea-Young Lee, Sydney Corey, Lauren Kvederis, Chase Kingsbury, Yuji Kaneko, Cesar V Borlongan
Publikováno v:
Neural Regeneration Research, Vol 14, Iss 4, Pp 597-604 (2019)
Transplantation of human bone marrow mesenchymal stem cells (hMSCs) stands as a potent stroke therapy, but its exact mechanism remains unknown. This study investigated the anti-apoptotic mechanisms by which hMSCs exert neuroprotective effects on cere
Externí odkaz:
https://doaj.org/article/1d3eedd8cbff4d82848a51f0b1d41516
Autor:
Jea-young Lee, Vanessa Castelli, Brooke Bonsack, Julián García-Sánchez, Chase Kingsbury, Hung Nguyen, Naoki Tajiri, Cesar V. Borlongan
Publikováno v:
Cell Transplantation, Vol 29 (2020)
Middle cerebral artery occlusion in rodents remains a widely used model of ischemic stroke. Recently, we reported the occurrence of retinal ischemia in animals subjected to middle cerebral artery occlusion, owing in part to the circulatory juxtaposit
Externí odkaz:
https://doaj.org/article/7246550e4db6485a827e249baf29d992