Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Chase K.A. Neumann"'
MBOAT7-driven phosphatidylinositol remodeling promotes the progression of clear cell renal carcinoma
Autor:
Chase K.A. Neumann, Daniel J. Silver, Varadharajan Venkateshwari, Renliang Zhang, C. Alicia Traughber, Christopher Przybycin, Defne Bayik, Jonathan D. Smith, Justin D. Lathia, Brian I. Rini, J. Mark Brown
Publikováno v:
Molecular Metabolism, Vol 34, Iss , Pp 136-145 (2020)
Objective: The most common kidney cancer, clear cell renal cell carcinoma (ccRCC), is closely associated with obesity. The “clear cell” variant of RCC gets its name from the large lipid droplets that accumulate in the tumor cells. Although renal
Externí odkaz:
https://doaj.org/article/858d7c85e7fc48f1814d38372a71bf64
Autor:
Scott M. Welford, Timothy J. Garrett, J. Mark Brown, Mark L. Gonzalgo, Hamzah H. Ahmed, Marco Dispagna, Rutulkumar Patel, Anthony J. Griswold, Chase K.A. Neumann, Michelle Puchowicz, Flavia Fontanesi, Iqbal Mahmud, Sze Kiat Tan
Clear cell renal cell carcinoma (ccRCC) is characterized by accumulation of neutral lipids and adipogenic transdifferentiation. We assessed adipokine expression in ccRCC and found that tumor tissues and patient plasma exhibit obesity-dependent elevat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d8beb65534517c82e48e504f1d88b35
https://doi.org/10.1158/2159-8290.c.6549287
https://doi.org/10.1158/2159-8290.c.6549287
Autor:
Scott M. Welford, Timothy J. Garrett, J. Mark Brown, Mark L. Gonzalgo, Hamzah H. Ahmed, Marco Dispagna, Rutulkumar Patel, Anthony J. Griswold, Chase K.A. Neumann, Michelle Puchowicz, Flavia Fontanesi, Iqbal Mahmud, Sze Kiat Tan
Differential expression of genes between ccRCC cluster and normal cluster
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78fe703c1bdfd36f7e46a45f9feae3a4
https://doi.org/10.1158/2159-8290.22540118
https://doi.org/10.1158/2159-8290.22540118
Autor:
Scott M. Welford, Timothy J. Garrett, J. Mark Brown, Mark L. Gonzalgo, Hamzah H. Ahmed, Marco Dispagna, Rutulkumar Patel, Anthony J. Griswold, Chase K.A. Neumann, Michelle Puchowicz, Flavia Fontanesi, Iqbal Mahmud, Sze Kiat Tan
Supplementary data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a81c3092a6b6aa42722a4b7ee555959c
https://doi.org/10.1158/2159-8290.22540124.v1
https://doi.org/10.1158/2159-8290.22540124.v1
Autor:
Jonathan D. Smith, Kailash Gulshan, Nima Sharifi, J. Mark Brown, Emmanuel Opoku, Jennifer Major, Hanxu Lu, Shuhui Wang Lorkowski, C. Alicia Traughber, Gregory Brubaker, Aimalie Hardaway, Yoon-Mi Chung, Chase K.A. Neumann
Publikováno v:
J Biol Chem
High-density lipoprotein (HDL) metabolism is facilitated in part by scavenger receptor class B, type 1 (SR-B1) that mediates HDL uptake into cells. Higher levels of HDL have been associated with protection in other diseases, however, its role in pros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58fa2418d971e73fce674eb77f5ddb4f
https://doi.org/10.1074/jbc.ra120.013694
https://doi.org/10.1074/jbc.ra120.013694
MBOAT7-driven phosphatidylinositol remodeling promotes the progression of clear cell renal carcinoma
Autor:
Jonathan D. Smith, Varadharajan Venkaleshwari, Daniel J. Silver, Justin D. Lathia, Defne Bayik, Brian I. Rini, Chase K.A. Neumann, Renliang Zhang, C. Alicia Traughber, J. Mark Brown, Christopher G. Przybycin
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 34, Iss, Pp 136-145 (2020)
Molecular Metabolism, Vol 34, Iss, Pp 136-145 (2020)
Objective: The most common kidney cancer, clear cell renal cell carcinoma (ccRCC), is closely associated with obesity. The “clear cell” variant of RCC gets its name from the large lipid droplets that accumulate in the tumor cells. Although renal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c81723f5ad4399f33d21b77f6c98e959
http://europepmc.org/articles/PMC7033598
http://europepmc.org/articles/PMC7033598
Autor:
Jonathan D. Smith, Jennifer Major, Aimalie Hardaway, Kailash Gulshan, Emmanuel Opoku, Gregory Brubaker, Nima Sharifi, C. Alicia Traughber, Hanxu Lu, Yoon-Mi Chung, Shuhui Wang Lorkowski, Chase K.A. Neumann, J. Mark Brown
High density lipoprotein (HDL) metabolism, in part, is facilitated by scavenger receptor class B, type 1 (SR-B1) that mediates its uptake into cells. SR-B1 is upregulated in prostate cancer tissue. Here, we report that knockout (KO) of SR-B1 via CRIS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66bddb0092f8c0c37f14e263597c08e5
https://doi.org/10.1101/2020.02.24.963454
https://doi.org/10.1101/2020.02.24.963454