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Penicillin susceptibility among Staphylococcus aureus skin and soft tissue infections at a children's hospital.

Autor: McNeil JC; Department of Pediatrics, Division of Infectious Diseases, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas, USA., Sommer LM; Department of Pediatrics, Division of Infectious Diseases, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas, USA., Joseph M; Department of Pediatrics, Division of Infectious Diseases, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas, USA., Hulten KG; Department of Pediatrics, Division of Infectious Diseases, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas, USA., Kaplan SL; Department of Pediatrics, Division of Infectious Diseases, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas, USA.

Publikováno v: Microbiology spectrum [Microbiol Spectr] 2024 Oct 03; Vol. 12 (10), pp. e0086924. Date of Electronic Publication: 2024 Sep 09.

CD4 ⁺ T cells exhibit distinct transcriptional phenotypes in the lymph nodes and blood following mRNA vaccination in humans.

Autor: Borcherding N; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO, USA., Kim W; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO, USA.; Department of Microbiology, Korea University College of Medicine, Seoul, Korea., Quinn M; Division of Infectious Diseases, Department of Pediatrics, Washington University School of Medicine, Saint Louis, MO, USA., Han F; Department of Emergency Medicine, Washington University School of Medicine, Saint Louis, MO, USA., Zhou JQ; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO, USA., Sturtz AJ; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO, USA., Schmitz AJ; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO, USA., Lei T; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO, USA., Schattgen SA; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA., Klebert MK; Clinical Trials Unit, Washington University School of Medicine, Saint Louis, MO, USA., Suessen T; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO, USA., Middleton WD; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO, USA., Goss CW; Division of Biostatistics, Washington University School of Medicine, Saint Louis, MO, USA., Liu C; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO, USA., Crawford JC; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA., Thomas PG; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA., Teefey SA; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO, USA., Presti RM; Clinical Trials Unit, Washington University School of Medicine, Saint Louis, MO, USA.; Division of Infectious Diseases, Department of Internal Medicine, Washington University School of Medicine, Saint Louis, MO, USA.; Center for Vaccines and Immunity to Microbial Pathogens, Washington University School of Medicine, Saint Louis, MO, USA.; The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, Saint Louis, MO, USA., O'Halloran JA; Division of Infectious Diseases, Department of Internal Medicine, Washington University School of Medicine, Saint Louis, MO, USA., Turner JS; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO, USA., Ellebedy AH; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO, USA. ellebedy@wustl.edu.; Center for Vaccines and Immunity to Microbial Pathogens, Washington University School of Medicine, Saint Louis, MO, USA. ellebedy@wustl.edu.; The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, Saint Louis, MO, USA. ellebedy@wustl.edu., Mudd PA; Department of Emergency Medicine, Washington University School of Medicine, Saint Louis, MO, USA. pmudd@wustl.edu.; Center for Vaccines and Immunity to Microbial Pathogens, Washington University School of Medicine, Saint Louis, MO, USA. pmudd@wustl.edu.; The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, Saint Louis, MO, USA. pmudd@wustl.edu.

Publikováno v: Nature immunology [Nat Immunol] 2024 Sep; Vol. 25 (9), pp. 1731-1741. Date of Electronic Publication: 2024 Aug 20.

High expression of oleoyl-ACP hydrolase underpins life-threatening respiratory viral diseases.

Autor: Jia X; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., Crawford JC; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Center for Infectious Diseases Research, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address: jeremy.crawford@stjude.org., Gebregzabher D; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., Monson EA; Department of Microbiology, Anatomy, Physiology and Pharmacology, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, VIC 3086, Australia., Mettelman RC; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Wan Y; Shanghai Public Health Clinical Centre and Institutes of Biomedical Sciences, Key Laboratory of Medical Molecular Virology of Ministry of Education/Health, Shanghai Medical College, Fudan University, Shanghai 201508, China., Ren Y; Shanghai Public Health Clinical Centre, Fudan University, Shanghai 201508, China., Chou J; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA., Novak T; Department of Anesthesiology, Critical Care, and Pain Medicine, Boston Children's Hospital and Department of Anaesthesia, Harvard Medical School, Boston, MA 02115, USA., McQuilten HA; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., Clarke M; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., Bachem A; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., Foo IJ; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., Fritzlar S; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., Carrera Montoya J; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., Trenerry AM; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., Nie S; Melbourne Mass Spectrometry and Proteomics Facility, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC 3052, Australia., Leeming MG; Melbourne Mass Spectrometry and Proteomics Facility, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC 3052, Australia., Nguyen THO; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., Kedzierski L; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., Littler DR; Infection and Immunity Program, Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia., Kueh A; Walter Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, VIC 3010, Australia; Olivia Newton-John Cancer Research Institute, Heidelberg, VIC 3084, Australia; School of Cancer Medicine, La Trobe University, Bundoora, VIC 3086, Australia., Cardamone T; Department of Anatomy and Physiology, University of Melbourne, Parkville, VIC 3010, Australia., Wong CY; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., Hensen L; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., Cabug A; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., Laguna JG; Department of Anatomy and Comparative Pathology and Toxicology, Pathology and Immunology Group, University of Córdoba, International Excellence Agrifood Campus 'CeiA3', 14014 Córdoba, Spain., Agrawal M; Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38163, USA., Flerlage T; Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Boyd DF; Department of Molecular, Cell & Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA 95064, USA., Van de Velde LA; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Habel JR; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., Loh L; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., Koay HF; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., van de Sandt CE; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., Konstantinov IE; Department of Cardiothoracic Surgery, Royal Children's Hospital, University of Melbourne, Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine, Parkville, VIC 3052, Australia., Berzins SP; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia; Institute of Innovation, Science and Sustainability, Federation University Australia, Ballarat, VIC 3353, Australia., Flanagan KL; School of Health Sciences and School of Medicine, University of Tasmania, Launceston, TAS 7248, Australia; School of Health and Biomedical Science, RMIT University, Bundoora, VIC 3083, Australia; Tasmanian Vaccine Trial Centre, Clifford Craig Foundation, Launceston General Hospital, Launceston, TAS 7250, Australia., Wakim LM; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., Herold MJ; Walter Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, VIC 3010, Australia; Olivia Newton-John Cancer Research Institute, Heidelberg, VIC 3084, Australia; School of Cancer Medicine, La Trobe University, Bundoora, VIC 3086, Australia., Green AM; Center for Infectious Diseases Research, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Smallwood HS; Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38163, USA., Rossjohn J; Infection and Immunity Program, Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia; Institute of Infection and Immunity, School of Medicine, Cardiff University, Heath Park, Cardiff, UK., Thwaites RS; National Heart and Lung Institute, Imperial College London, London SW7 2AZ, UK., Chiu C; Department of Infectious Disease, Imperial College London, London, UK., Scott NE; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., Mackenzie JM; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., Bedoui S; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., Reading PC; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., Londrigan SL; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., Helbig KJ; Department of Microbiology, Anatomy, Physiology and Pharmacology, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, VIC 3086, Australia., Randolph AG; Department of Anesthesiology, Critical Care, and Pain Medicine, Boston Children's Hospital and Department of Anaesthesia, Harvard Medical School, Boston, MA 02115, USA; Center for Influenza Disease and Emergence Response (CIDER), Athens, GA, USA., Thomas PG; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Center for Infectious Diseases Research, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Center for Influenza Disease and Emergence Response (CIDER), Athens, GA, USA., Xu J; Shanghai Public Health Clinical Centre and Institutes of Biomedical Sciences, Key Laboratory of Medical Molecular Virology of Ministry of Education/Health, Shanghai Medical College, Fudan University, Shanghai 201508, China., Wang Z; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia; State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, Guangzhou Medical University, Guangzhou, China. Electronic address: wangzhongfang@gird.cn., Chua BY; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia. Electronic address: bychua@unimelb.edu.au., Kedzierska K; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia; Center for Influenza Disease and Emergence Response (CIDER), Athens, GA, USA. Electronic address: kkedz@unimelb.edu.au.

Publikováno v: Cell [Cell] 2024 Aug 22; Vol. 187 (17), pp. 4586-4604.e20. Date of Electronic Publication: 2024 Aug 12.