Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Charu Kapil"'
Autor:
Ulrike Kusebauch, Alan P. R. Lorenzetti, David S. Campbell, Min Pan, David Shteynberg, Charu Kapil, Mukul K. Midha, Adrián López García de Lomana, Nitin S. Baliga, Robert L. Moritz
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-14 (2023)
Abstract Data-Independent Acquisition (DIA) is a mass spectrometry-based method to reliably identify and reproducibly quantify large fractions of a target proteome. The peptide-centric data analysis strategy employed in DIA requires a priori generate
Externí odkaz:
https://doaj.org/article/43933e8e04844f75b041f4a5e2a61de9
Autor:
Kengo Watanabe, Tomasz Wilmanski, Priyanka Baloni, Max Robinson, Gonzalo G. Garcia, Michael R. Hoopmann, Mukul K. Midha, David H. Baxter, Michal Maes, Seamus R. Morrone, Kelly M. Crebs, Charu Kapil, Ulrike Kusebauch, Jack Wiedrick, Jodi Lapidus, Lance Pflieger, Christopher Lausted, Jared C. Roach, Gwênlyn Glusman, Steven R. Cummings, Nicholas J. Schork, Nathan D. Price, Leroy Hood, Richard A. Miller, Robert L. Moritz, Noa Rappaport
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Abstract Aging manifests as progressive deteriorations in homeostasis, requiring systems-level perspectives to investigate the gradual molecular dysregulation of underlying biological processes. Here, we report systemic changes in the molecular regul
Externí odkaz:
https://doaj.org/article/62bd4731cc7d4a7caaf5b70a9897021a
Autor:
Kengo Watanabe, Tomasz Wilmanski, Priyanka Baloni, Max Robinson, Gonzalo G. Garcia, Michael R. Hoopmann, Mukul K. Midha, David H. Baxter, Michal Maes, Seamus R. Morrone, Kelly M. Crebs, Charu Kapil, Ulrike Kusebauch, Jack Wiedrick, Jodi Lapidus, Lance Pflieger, Christopher Lausted, Jared C. Roach, Gwênlyn Glusman, Steven R. Cummings, Nicholas J. Schork, Nathan D. Price, Leroy Hood, Richard A. Miller, Robert L. Moritz, Noa Rappaport
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/a9aff2da020c40e2bb53670b91526adc
Autor:
Harshi Weerakoon, Jeremy Potriquet, Alok K. Shah, Sarah Reed, Buddhika Jayakody, Charu Kapil, Mukul K. Midha, Robert L. Moritz, Ailin Lepletier, Jason Mulvenna, John J. Miles, Michelle M. Hill
Publikováno v:
Scientific Data, Vol 7, Iss 1, Pp 1-9 (2020)
Measurement(s) Proteome • protein expression data Technology Type(s) Proteomic Profiling • nanoflow liquid chromatography-tandem mass spectrometry • SWATH MS protein profiling assay • Data-Dependent Acquisition • mass spectrometry Factor Ty
Externí odkaz:
https://doaj.org/article/c39eb5f546ac4ddab0c080896f2affe2
Autor:
Mukul K. Midha, David S. Campbell, Charu Kapil, Ulrike Kusebauch, Michael R. Hoopmann, Samuel L. Bader, Robert L. Moritz
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Most data-independent acquisition (DIA) methods depend on mass spectral libraries for peptide identification but tools to assess library quality are lacking. Here, the authors develop DIALib- QC for the systematic evaluation and correction of spectra
Externí odkaz:
https://doaj.org/article/ccccc74826bf401a9cfbc10bc90926c1
Autor:
Teena Bhakuni, Amit Sharma, Qudsia Rashid, Charu Kapil, Renu Saxena, Manoranjan Mahapatra, Mohamad Aman Jairajpuri
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121889 (2015)
Antithrombin III (AT) is the main inhibitor of blood coagulation proteases like thrombin and factor Xa. In this study we report the identification and characterization of several variants of AT for the first time in Indian population. We screened 195
Externí odkaz:
https://doaj.org/article/e9ca1b93785846e388d0befebf6f8696
Autor:
Mukul K. Midha, Charu Kapil, Michal Maes, David H. Baxter, Seamus R. Morrone, Timothy J. Prokop, Robert L. Moritz
Publikováno v:
bioRxiv
By far the largest contribution to ion detectability in liquid chromatography-driven mass spectrometry-based proteomics is the efficient generation of peptide ions by the electrospray source. To maximize the transfer of peptides from liquid to a gase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4071303b92e2a4210a6fced492750e60
https://doi.org/10.1101/2023.02.15.528699
https://doi.org/10.1101/2023.02.15.528699
Autor:
Kengo Watanabe, Tomasz Wilmanski, Priyanka Baloni, Max Robinson, Gonzalo G. Garcia, Michael R. Hoopmann, Mukul K. Midha, David H. Baxter, Michal Maes, Seamus R. Morrone, Kelly M. Crebs, Charu Kapil, Ulrike Kusebauch, Jack Wiedrick, Jodi Lapidus, Jennifer C. Lovejoy, Andrew T. Magis, Christopher Lausted, Jared C. Roach, Gustavo Glusman, Steven R. Cummings, Nicholas J. Schork, Nathan D. Price, Leroy Hood, Richard A. Miller, Robert L. Moritz, Noa Rappaport
Aging manifests as progressive deterioration in cellular and systemic homeostasis, requiring systems-level perspectives to understand the gradual molecular dysregulation of underlying biological processes. Here, we report systems-level changes in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51da11411750ecf5a67036950eb72812
https://doi.org/10.1101/2022.07.11.22277435
https://doi.org/10.1101/2022.07.11.22277435
Autor:
John J. Miles, Robert L. Moritz, Ailin Lepletier, Alok K. Shah, Jason Mulvenna, Charu Kapil, Michelle M. Hill, Jeremy Potriquet, Buddhika Jayakody, Harshi Weerakoon, Sarah Reed, Mukul K. Midha
Publikováno v:
Scientific Data
Scientific Data, Vol 7, Iss 1, Pp 1-9 (2020)
Scientific Data, Vol 7, Iss 1, Pp 1-9 (2020)
Data independent analysis (DIA) exemplified by sequential window acquisition of all theoretical mass spectra (SWATH-MS) provides robust quantitative proteomics data, but the lack of a public primary human T-cell spectral library is a current resource
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adab0bfbe635269d63a1db5cbb6ea4e8
https://doi.org/10.1038/s41597-020-00744-3
https://doi.org/10.1038/s41597-020-00744-3
Autor:
David Shteynberg, Charu Kapil, Nitin S. Baliga, Ulrike Kusebauch, Panga Jaipal Reddy, Mukul K. Midha, Samuel L. Bader, Robert L. Moritz, David S. Campbell
Publikováno v:
Scientific Data
Scientific Data, Vol 7, Iss 1, Pp 1-12 (2020)
Scientific Data, Vol 7, Iss 1, Pp 1-12 (2020)
Data-Independent Acquisition (DIA) is a method to improve consistent identification and precise quantitation of peptides and proteins by mass spectrometry (MS). The targeted data analysis strategy in DIA relies on spectral assay libraries that are ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b00820e92f782b3b0a8dc980700a256
http://europepmc.org/articles/PMC7665006
http://europepmc.org/articles/PMC7665006