Tissue mechanics modulate morphogen signalling to induce the head organiser.

Autor: Bubna-Litic M; Department of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK., Charras G; Department of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK; London Centre for Nanotechnology, University College London, Gordon St, London WC1H 0AH, UK., Mayor R; Department of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK; Center for Integrative Biology, Faculty of Sciences, Universidad Mayor, Santiago, Chile. Electronic address: r.mayor@ucl.ac.uk.

Publikováno v: Cells & development [Cells Dev] 2024 Dec 02, pp. 203984. Date of Electronic Publication: 2024 Dec 02.

Sustained Strain Applied at High Rates Drives Dynamic Tensioning in Epithelial Cells.

Autor: Safa BT; Department of Mechanical and Materials Engineering, University of Nebraska-Lincoln, Lincoln, NE, USA., Rosenbohm J; Department of Mechanical and Materials Engineering, University of Nebraska-Lincoln, Lincoln, NE, USA., Esfahani AM; Department of Mechanical and Materials Engineering, University of Nebraska-Lincoln, Lincoln, NE, USA., Minnick G; Department of Mechanical and Materials Engineering, University of Nebraska-Lincoln, Lincoln, NE, USA., Moghaddam AO; Department of Mechanical and Materials Engineering, University of Nebraska-Lincoln, Lincoln, NE, USA., Lavrik NV; Center for Nanophase Materials Sciences, Oak Ridge National Laboratory, Oak Ridge, TN, USA., Huang C; School of Mechanical & Aerospace Engineering, Nanyang Technological University, Singapore, Republic of Singapore., Charras G; London Centre for Nanotechnology, University College London, London, UK.; Department of Cell and Developmental Biology, University College London, London, UK.; Institute for the Physics of Living Systems, University College London, London, UK., Kabla A; Department of Engineering, University of Cambridge, Cambridge, UK., Yang R; Department of Mechanical and Materials Engineering, University of Nebraska-Lincoln, Lincoln, NE, USA.; Department of Biomedical Engineering, Michigan State University, East Lansing, MI, USA.; Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, MI, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Aug 01. Date of Electronic Publication: 2024 Aug 01.

AMPK is a mechano-metabolic sensor linking cell adhesion and mitochondrial dynamics to Myosin-dependent cell migration.

Autor: Crosas-Molist E; Barts Cancer Institute, Queen Mary University of London, John Vane Science Building, Charterhouse Square, London, EC1M 6BQ, UK.; Randall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK., Graziani V; Barts Cancer Institute, Queen Mary University of London, John Vane Science Building, Charterhouse Square, London, EC1M 6BQ, UK.; Randall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK., Maiques O; Barts Cancer Institute, Queen Mary University of London, John Vane Science Building, Charterhouse Square, London, EC1M 6BQ, UK.; Randall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK., Pandya P; Randall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK., Monger J; Barts Cancer Institute, Queen Mary University of London, John Vane Science Building, Charterhouse Square, London, EC1M 6BQ, UK., Samain R; Barts Cancer Institute, Queen Mary University of London, John Vane Science Building, Charterhouse Square, London, EC1M 6BQ, UK., George SL; Barts Cancer Institute, Queen Mary University of London, John Vane Science Building, Charterhouse Square, London, EC1M 6BQ, UK., Malik S; Randall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK., Salise J; Randall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK.; Centre for Biomolecular Spectroscopy, King's College London, London, SE1 1UL, UK., Morales V; Barts Cancer Institute, Queen Mary University of London, John Vane Science Building, Charterhouse Square, London, EC1M 6BQ, UK., Le Guennec A; Randall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK.; Centre for Biomolecular Spectroscopy, King's College London, London, SE1 1UL, UK., Atkinson RA; Randall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK.; Centre for Biomolecular Spectroscopy, King's College London, London, SE1 1UL, UK.; Institut de Pharmacologie et de Biologie Structurale (IPBS), UMR5089, CNRS-Université de Toulouse III-Paul Sabatier, BP 64182, 31077, Toulouse, Cedex 4, France., Marti RM; Department of Dermatology, Hospital Universitari Arnau de Vilanova, University of Lleida, CIBERONC, IRB Lleida, Lleida, 25198, Spain., Matias-Guiu X; Department of Pathology and Molecular Genetics, Hospital Universitari Arnau de Vilanova, University of Lleida, IRB Lleida, CIBERONC, Lleida, 25198, Spain.; Department of Pathology, Hospital Universitari de Bellvitge, University of Barcelona, IDIBELL, CIBERONC, L'Hospitalet de Llobregat, Barcelona, 08907, Spain., Charras G; London Centre for Nanotechnology, University College London, London, WC1H 0AH, UK.; Department of Cell and Developmental Biology, University College London, London, WC1E 6BT, UK., Conte MR; Randall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK.; Centre for Biomolecular Spectroscopy, King's College London, London, SE1 1UL, UK., Elosegui-Artola A; Cell and Tissue Mechanobiology Lab, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.; Department of Physics, King's College London, London, WC2R 2LS, UK., Holt M; Randall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK.; School of Cardiovascular and Metabolic Medicine & Sciences, King's College London BHF Centre of Research Excellence, London, SE1 1UL, UK., Sanz-Moreno V; Barts Cancer Institute, Queen Mary University of London, John Vane Science Building, Charterhouse Square, London, EC1M 6BQ, UK. v.sanz-moreno@qmul.ac.uk.; Randall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK. v.sanz-moreno@qmul.ac.uk.

Publikováno v: Nature communications [Nat Commun] 2023 May 22; Vol. 14 (1), pp. 2740. Date of Electronic Publication: 2023 May 22.

SPIN90 associates with mDia1 and the Arp2/3 complex to regulate cortical actin organization.

Autor: Cao L; Université de Paris, CNRS, Institut Jacques Monod, Paris, France., Yonis A; London Centre for Nanotechnology, University College London, London, UK.; Department of Cell and Developmental Biology, University College London, London, UK., Vaghela M; London Centre for Nanotechnology, University College London, London, UK.; Department of Physics and Astronomy, University College London, London, UK., Barriga EH; Department of Cell and Developmental Biology, University College London, London, UK.; Instituto Gulbenkian de Ciência, Oeiras, Portugal., Chugh P; MRC-Laboratory for Molecular Cell Biology, University College London, London, UK., Smith MB; MRC-Laboratory for Molecular Cell Biology, University College London, London, UK.; The Francis Crick institute, London, UK., Maufront J; Laboratoire Physico Chimie Curie, Institut Curie, PSL Research University, CNRS UMR168, Paris, France.; Sorbonne Universités, Paris, France., Lavoie G; Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Quebec, Canada., Méant A; Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Quebec, Canada., Ferber E; London Centre for Nanotechnology, University College London, London, UK., Bovellan M; London Centre for Nanotechnology, University College London, London, UK.; Department of Cell and Developmental Biology, University College London, London, UK., Alberts A; Van Andel research institute, Grand Rapids, MI, USA., Bertin A; Laboratoire Physico Chimie Curie, Institut Curie, PSL Research University, CNRS UMR168, Paris, France.; Sorbonne Universités, Paris, France., Mayor R; Department of Cell and Developmental Biology, University College London, London, UK., Paluch EK; MRC-Laboratory for Molecular Cell Biology, University College London, London, UK.; Institute for the Physics of Living Systems, University College London, London, UK.; Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK., Roux PP; Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Quebec, Canada.; Department of Pathology and Cell Biology, Université de Montréal, Montréal, Canada., Jégou A; Université de Paris, CNRS, Institut Jacques Monod, Paris, France. antoine.jegou@ijm.fr., Romet-Lemonne G; Université de Paris, CNRS, Institut Jacques Monod, Paris, France. romet@ijm.fr., Charras G; London Centre for Nanotechnology, University College London, London, UK. g.charras@ucl.ac.uk.; Department of Cell and Developmental Biology, University College London, London, UK. g.charras@ucl.ac.uk.; Institute for the Physics of Living Systems, University College London, London, UK. g.charras@ucl.ac.uk.

Publikováno v: Nature cell biology [Nat Cell Biol] 2020 Jul; Vol. 22 (7), pp. 803-814. Date of Electronic Publication: 2020 Jun 22.

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