Aspergillus antigen induces robust Th2 cytokine production, inflammation, airway hyperreactivity and fibrosis in the absence of MCP-1 or CCR2

Autor: Koth, L L, Rodriguez, M W, Bernstein, X L, Chan, S, Huang, X Z, Charo, I F, Rollins, B J, Erle, David J

Publikováno v: Koth, L L; Rodriguez, M W; Bernstein, X L; Chan, S; Huang, X Z; Charo, I F; et al.(2004). Aspergillus antigen induces robust Th2 cytokine production, inflammation, airway hyperreactivity and fibrosis in the absence of MCP-1 or CCR2. Respiratory Research, 5(11-12). UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/8rz8r35x

Background: Asthma is characterized by type 2 T-helper cell (Th2) inflammation, goblet cell hyperplasia, airway hyperreactivity, and airway fibrosis. Monocyte chemoattractant protein-1 (MCP-1 or CCL2) and its receptor, CCR2, have been shown to play i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::0d4c4973f78652d0df639825e4794d1c
http://www.escholarship.org/uc/item/8rz8r35x

The relative contributions of each subset of ocular infiltrated cells in experimental choroidal neovascularisation.

Autor: Tsutsumi-Miyahara, C., Sonoda, K. -H., Egashira, K., Ishibashi, M., Qiao, H., Oshima, T., Murata, T., Miyazaki, M., Charo, I. F., Hamano, S., Ishibashi, T.

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Molecular uncoupling of fractalkine-mediated cell adhesion and signal transduction. Rapid flow arrest of CX3CR1-expressing cells is independent of G-protein activation.

Autor: Haskell, C A, Cleary, M D, Charo, I F

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Autor: Monteclaro, F S, Charo, I F

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The amino-terminal domain of CCR2 is both necessary and sufficient for high affinity binding of monocyte chemoattractant protein 1. Receptor activation by a pseudo-tethered ligand.

Autor: Monteclaro, F S, Charo, I F

Publikováno v: Journal of Biological Chemistry; September 1997, Vol. 272 Issue: 37 p23186-90, 5p