Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Charmaine J Simeonovic"'
Autor:
Sarita Dhounchak, Sarah K Popp, Debra J Brown, D Ross Laybutt, Trevor J Biden, Stefan R Bornstein, Christopher R Parish, Charmaine J Simeonovic
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0252607 (2021)
Heparan sulfate proteoglycans (HSPGs) consist of a core protein with side chains of the glycosaminoglycan heparan sulfate (HS). We have previously identified (i) the HSPGs syndecan-1 (SDC1), and collagen type XVIII (COL18) inside mouse and human isle
Externí odkaz:
https://doaj.org/article/68eb3c59062444408e639f2ff92b388d
Autor:
Charmaine J Simeonovic, Sarah K Popp, Lora M Starrs, Debra J Brown, Andrew F Ziolkowski, Barbara Ludwig, Stefan R Bornstein, J Dennis Wilson, Alberto Pugliese, Thomas W H Kay, Helen E Thomas, Thomas Loudovaris, Fui Jiun Choong, Craig Freeman, Christopher R Parish
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0191360 (2018)
Type 1 diabetes (T1D) is an autoimmune disease in which insulin-producing beta cells in pancreatic islets are progressively destroyed. Clinical trials of immunotherapies in recently diagnosed T1D patients have only transiently and partially impacted
Externí odkaz:
https://doaj.org/article/3bfbd0d7d48b4557a8441d019c004f28
Autor:
Steffi Kopprasch, Srirangan Dheban, Kai Schuhmann, Aimin Xu, Klaus-Martin Schulte, Charmaine J Simeonovic, Peter E H Schwarz, Stefan R Bornstein, Andrej Shevchenko, Juergen Graessler
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164173 (2016)
OBJECTIVE:Glucolipotoxicity is a major pathophysiological mechanism in the development of insulin resistance and type 2 diabetes mellitus (T2D). We aimed to detect subtle changes in the circulating lipid profile by shotgun lipidomics analyses and to
Externí odkaz:
https://doaj.org/article/75246a90e8514cf3a0228cdcb8528073
Autor:
Alessandra, Petrelli, Sarah K, Popp, Riho, Fukuda, Christopher R, Parish, Emanuele, Bosi, Charmaine J, Simeonovic
Publikováno v:
Frontiers in Immunology. 13
Type 1 diabetes (T1D) is an autoimmune disease resulting from the destruction of insulin-producing beta cells in pancreatic islets. T lymphocytes are the claimed pathogenic effectors but abnormalities of other immune cell types, including neutrophils
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ee80096509d55149fb2ea2923be123d
https://doi.org/10.3389/fimmu.2022.930553
https://doi.org/10.3389/fimmu.2022.930553
Autor:
Zuopeng Wu, Rebecca A. Sweet, Gerard F. Hoyne, Charmaine J. Simeonovic, Christopher R. Parish
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 9; Pages: 4625
It has been accepted for decades that T lymphocytes and metastasising tumour cells traverse basement membranes (BM) by deploying a battery of degradative enzymes, particularly proteases. However, since many redundant proteases can solubilise BM it ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5ae9dab46a2aac3bf89b47a58306983
https://pubmed.ncbi.nlm.nih.gov/35563015
https://pubmed.ncbi.nlm.nih.gov/35563015
Autor:
Sarah K. Popp, Federica Vecchio, Debra J. Brown, Riho Fukuda, Yuri Suzuki, Yuma Takeda, Rikako Wakamatsu, Mahalakshmi A. Sarma, Jessica Garrett, Anna Giovenzana, Emanuele Bosi, Antony R.A. Lafferty, Karen J. Brown, Elizabeth E. Gardiner, Lucy A. Coupland, Helen E. Thomas, Beng H. Chong, Christopher R. Parish, Manuela Battaglia, Alessandra Petrelli, Charmaine J. Simeonovic
Publikováno v:
JCI Insight. 7
Platelet-neutrophil aggregates (PNAs) facilitate neutrophil activation and migration and could underpin the recruitment of neutrophils to the pancreas during type 1 diabetes (T1D) pathogenesis. PNAs, measured by flow cytometry, were significantly ele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0549b1397607c815ab52c1e3f9579695
https://doi.org/10.1172/jci.insight.153993
https://doi.org/10.1172/jci.insight.153993
Autor:
Nadine Nagy, Pamela Y. Johnson, Christina K. Chan, Marika Bogdani, Thomas N. Wight, Charmaine J. Simeonovic
Publikováno v:
Methods in Molecular Biology ISBN: 9781071613979
Methods in Molecular Biology
Methods in Molecular Biology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bb921eb777fc345dc1bffd9f8ca9773
https://doi.org/10.1007/978-1-0716-1398-6_53
https://doi.org/10.1007/978-1-0716-1398-6_53
Autor:
Sarah K. Popp, Christopher R. Parish, Charmaine J. Simeonovic, Trevor J. Biden, Sarita Dhounchak, D. Ross Laybutt, Debra J. Brown, Stefan R. Bornstein
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 6, p e0252607 (2021)
PLoS ONE, Vol 16, Iss 6, p e0252607 (2021)
Heparan sulfate proteoglycans (HSPGs) consist of a core protein with side chains of the glycosaminoglycan heparan sulfate (HS). We have previously identified (i) the HSPGs syndecan-1 (SDC1), and collagen type XVIII (COL18) inside mouse and human isle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f39bdc0d38a6741497adf8084e0053
https://pubmed.ncbi.nlm.nih.gov/34086738
https://pubmed.ncbi.nlm.nih.gov/34086738
Autor:
Charmaine J, Simeonovic, Sarah K, Popp, Debra J, Brown, Fei-Ju, Li, Antony R A, Lafferty, Craig, Freeman, Christopher R, Parish
Publikováno v:
Advances in experimental medicine and biology. 1221
Type 1 diabetes (T1D) results from autoimmune destruction of insulin-producing beta cells in pancreatic islets. The degradation of the glycosaminoglycan heparan sulfate (HS) by the endo-β-D-glycosidase heparanase plays a critical role in multiple st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5b5eadad7925d311d863c6ae86fdcbfa
https://pubmed.ncbi.nlm.nih.gov/32274728
https://pubmed.ncbi.nlm.nih.gov/32274728
Autor:
Fei-Ju Li, Antony R Lafferty, Debra J. Brown, Christopher R. Parish, Sarah K. Popp, Craig Freeman, Charmaine J. Simeonovic
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030345204
Type 1 diabetes (T1D) results from autoimmune destruction of insulin-producing beta cells in pancreatic islets. The degradation of the glycosaminoglycan heparan sulfate (HS) by the endo-β-D-glycosidase heparanase plays a critical role in multiple st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20b27eb3f944ed6eead155feda61973a
https://doi.org/10.1007/978-3-030-34521-1_24
https://doi.org/10.1007/978-3-030-34521-1_24